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7ALP
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BU of 7alp by Molmil
Severe fever with thrombocytopenia syndrome virus (Phenuiviridae) L protein
分子名称: MAGNESIUM ION, Replicase
著者Cusack, S, Rosenthal, M.
登録日2020-10-07
公開日2021-04-21
最終更新日2021-05-12
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Errors in the deposited SFTSV L protein structure.
Nat Microbiol, 6, 2021
1H3N
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BU of 1h3n by Molmil
Leucyl-tRNA synthetase from Thermus thermophilus complexed with a sulphamoyl analogue of leucyl-adenylate
分子名称: LEUCINE, LEUCYL-TRNA SYNTHETASE, SULFATE ION, ...
著者Cusack, S, Yaremchuk, A, Tukalo, M.
登録日2002-09-11
公開日2002-09-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The 2A Structure of Leucyl-tRNA Synthetase and its Complex with a Leucyl-Adenylate Analogue
Embo J., 19, 2000
1SET
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BU of 1set by Molmil
CRYSTAL STRUCTURES AT 2.5 ANGSTROMS RESOLUTION OF SERYL-TRNA SYNTHETASE COMPLEXED WITH TWO DIFFERENT ANALOGUES OF SERYL-ADENYLATE
分子名称: 5'-O-(N-(L-SERYL)-SULFAMOYL)ADENOSINE, SERYL-tRNA SYNTHETASE
著者Cusack, S, Belrhali, H.
登録日1994-02-21
公開日1994-07-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Crystal structures at 2.5 angstrom resolution of seryl-tRNA synthetase complexed with two analogs of seryl adenylate.
Science, 263, 1994
1SES
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BU of 1ses by Molmil
CRYSTAL STRUCTURES AT 2.5 ANGSTROMS RESOLUTION OF SERYL-TRNA SYNTHETASE COMPLEXED WITH TWO DIFFERENT ANALOGUES OF SERYL-ADENYLATE
分子名称: ADENOSINE MONOPHOSPHATE, SERYL-HYDROXAMATE-ADENOSINE MONOPHOSPHATE, SERYL-tRNA SYNTHETASE
著者Cusack, S, Belrhali, H.
登録日1994-02-21
公開日1994-07-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structures at 2.5 angstrom resolution of seryl-tRNA synthetase complexed with two analogs of seryl adenylate.
Science, 263, 1994
1OBH
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BU of 1obh by Molmil
LEUCYL-TRNA SYNTHETASE FROM THERMUS THERMOPHILUS COMPLEXED WITH A PRE-TRANSFER EDITING SUBSTRATE ANALOGUE IN BOTH SYNTHETIC ACTIVE SITE AND EDITING SITE
分子名称: LEUCYL-TRNA SYNTHETASE, MERCURY (II) ION, NORVALINE, ...
著者Cusack, S, Yaremchuk, A, Tukalo, M.
登録日2003-01-31
公開日2003-05-09
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural and Mechanistic Basis of Pre- and Posttransfer Editing by Leucyl-tRNA Synthetase
Mol.Cell, 11, 2003
1OBC
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BU of 1obc by Molmil
LEUCYL-TRNA SYNTHETASE FROM THERMUS THERMOPHILUS COMPLEXED WITH A POST-TRANSFER EDITING SUBSTRATE ANALOGUE
分子名称: 2'-AMINO-2'-DEOXYADENOSINE, LEUCINE, LEUCYL-TRNA SYNTHETASE, ...
著者Cusack, S, Yaremchuk, A, Tukalo, M.
登録日2003-01-30
公開日2003-05-09
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural and Mechanistic Basis of Pre- and Posttransfer Editing by Leucyl-tRNA Synthetase
Mol.Cell, 11, 2003
1ADJ
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BU of 1adj by Molmil
HISTIDYL-TRNA SYNTHETASE IN COMPLEX WITH HISTIDINE
分子名称: HISTIDINE, HISTIDYL-TRNA SYNTHETASE, SULFATE ION
著者Cusack, S, Aberg, A.
登録日1997-02-18
公開日1997-08-20
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure analysis of the activation of histidine by Thermus thermophilus histidyl-tRNA synthetase.
Biochemistry, 36, 1997
8BEK
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BU of 8bek by Molmil
Early transcription elongation state of influenza A/H7N9 backtracked polymerase with singly incoporated T1106 at the U +1 position
分子名称: 3' vRNA, 5' vRNA, MAGNESIUM ION, ...
著者Cusack, S, Kouba, T.
登録日2022-10-21
公開日2022-12-28
最終更新日2023-02-15
実験手法ELECTRON MICROSCOPY (2.86 Å)
主引用文献Direct observation of backtracking by influenza A and B polymerases upon consecutive incorporation of the nucleoside analog T1106.
Cell Rep, 42, 2023
8BE0
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BU of 8be0 by Molmil
Early transcription elongation state of influenza B/Mem polymerase backtracked due to double incoproation of nucleotide analogue T1106 and with singly incoporated T1106 at the C +1 position
分子名称: 3' vRNA, 5' vRNA, MAGNESIUM ION, ...
著者Cusack, S, Kouba, T.
登録日2022-10-20
公開日2022-12-28
最終更新日2023-02-15
実験手法ELECTRON MICROSCOPY (2.34 Å)
主引用文献Direct observation of backtracking by influenza A and B polymerases upon consecutive incorporation of the nucleoside analog T1106.
Cell Rep, 42, 2023
8BF5
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BU of 8bf5 by Molmil
Early transcription elongation state of influenza A/H7N9 polymerase stalled with incoming GTP analogue
分子名称: 3' vRNA, 5' vRNA, MAGNESIUM ION, ...
著者Cusack, S, Kouba, T.
登録日2022-10-24
公開日2022-12-28
最終更新日2023-02-15
実験手法ELECTRON MICROSCOPY (2.96 Å)
主引用文献Direct observation of backtracking by influenza A and B polymerases upon consecutive incorporation of the nucleoside analog T1106.
Cell Rep, 42, 2023
1ADY
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BU of 1ady by Molmil
HISTIDYL-TRNA SYNTHETASE IN COMPLEX WITH HISTIDYL-ADENYLATE
分子名称: HISTIDYL-ADENOSINE MONOPHOSPHATE, HISTIDYL-TRNA SYNTHETASE, SULFATE ION
著者Cusack, S, Aberg, A.
登録日1997-02-19
公開日1997-08-20
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure analysis of the activation of histidine by Thermus thermophilus histidyl-tRNA synthetase.
Biochemistry, 36, 1997
6QCX
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BU of 6qcx by Molmil
Crystal structure of influenza B polymerase initiation state with capped 15-mer RNA primer
分子名称: MAGNESIUM ION, PHOSPHATE ION, PYROPHOSPHATE 2-, ...
著者Cusack, S, Drncova, P.
登録日2018-12-31
公開日2019-06-05
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.08 Å)
主引用文献Structural snapshots of actively transcribing influenza polymerase.
Nat.Struct.Mol.Biol., 26, 2019
6QCV
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BU of 6qcv by Molmil
Crystal structure of influenza B polymerase initiation state with capped 14-mer RNA primer and CTP
分子名称: CYTIDINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PHOSPHATE ION, ...
著者Cusack, S, Drncova, P.
登録日2018-12-31
公開日2019-06-05
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.24 Å)
主引用文献Structural snapshots of actively transcribing influenza polymerase.
Nat.Struct.Mol.Biol., 26, 2019
7QTL
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BU of 7qtl by Molmil
Influenza A/H7N9 polymerase elongation complex
分子名称: 3' vRNA, 5' vRNA, 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]cytidine, ...
著者Cusack, S, Kouba, T.
登録日2022-01-14
公開日2022-12-28
最終更新日2023-02-15
実験手法ELECTRON MICROSCOPY (2.48 Å)
主引用文献Direct observation of backtracking by influenza A and B polymerases upon consecutive incorporation of the nucleoside analog T1106.
Cell Rep, 42, 2023
7R1F
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BU of 7r1f by Molmil
Early transcription elongation state of influenza B polymerase backtracked due to double incoproation of nucleotide analogue T1106
分子名称: 3' vRNA, 5' vRNA, MAGNESIUM ION, ...
著者Cusack, S, Kouba, T.
登録日2022-02-02
公開日2022-12-28
最終更新日2023-02-15
実験手法ELECTRON MICROSCOPY (2.58 Å)
主引用文献Direct observation of backtracking by influenza A and B polymerases upon consecutive incorporation of the nucleoside analog T1106.
Cell Rep, 42, 2023
7R0E
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BU of 7r0e by Molmil
Early transcription elongation state of influenza A/H7N9 polymerase backtracked due to double incoproation of nucleotide analogue T1106 and with singly incoporated T1106 at the +1 position
分子名称: 3' vRNA, 5' vRNA, MAGNESIUM ION, ...
著者Cusack, S, Kouba, T.
登録日2022-02-01
公開日2022-12-28
最終更新日2023-02-15
実験手法ELECTRON MICROSCOPY (2.51 Å)
主引用文献Direct observation of backtracking by influenza A and B polymerases upon consecutive incorporation of the nucleoside analog T1106.
Cell Rep, 42, 2023
6Z6B
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BU of 6z6b by Molmil
Structure of full-length La Crosse virus L protein (polymerase)
分子名称: RNA (5'-R(*GP*CP*UP*AP*CP*UP*AP*A)-3'), RNA (5'-R(P*AP*GP*UP*AP*GP*UP*GP*UP*GP*C)-3'), RNA (5'-R(P*UP*UP*AP*GP*UP*AP*GP*UP*AP*CP*AP*CP*UP*AP*CP*U)-3'), ...
著者Cusack, S, Gerlach, P, Reguera, J.
登録日2020-05-28
公開日2020-07-29
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3.961 Å)
主引用文献Pre-initiation and elongation structures of full-length La Crosse virus polymerase reveal functionally important conformational changes.
Nat Commun, 11, 2020
7Z43
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BU of 7z43 by Molmil
Influenza B polymerase with Pol II pSer5 CTD peptide mimic bound in site 1B and 2B
分子名称: PHOSPHATE ION, Polymerase acidic protein, Polymerase basic protein 2, ...
著者Cusack, S, Drncova, P.
登録日2022-03-03
公開日2022-05-11
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3.123 Å)
主引用文献Type B and type A influenza polymerases have evolved distinct binding interfaces to recruit the RNA polymerase II CTD.
Plos Pathog., 18, 2022
7Z4O
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BU of 7z4o by Molmil
Influenza A/H7N9 polymerase core dimer with Pol II pSer5 CTD peptide mimic bound in site 2A
分子名称: MAGNESIUM ION, Polymerase acidic protein, Polymerase basic protein 2, ...
著者Cusack, S, Pflug, A.
登録日2022-03-04
公開日2022-05-11
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3.412 Å)
主引用文献Type B and type A influenza polymerases have evolved distinct binding interfaces to recruit the RNA polymerase II CTD.
Plos Pathog., 18, 2022
7Z42
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BU of 7z42 by Molmil
Influenza B polymerase with Pol II pSer5 CTD peptide mimic bound in site 2B
分子名称: DNA-directed RNA polymerase II subunit RPB1, Polymerase acidic protein, Polymerase basic protein 2, ...
著者Cusack, S, Drncova, P.
登録日2022-03-03
公開日2022-05-18
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.418 Å)
主引用文献Type B and type A influenza polymerases have evolved distinct binding interfaces to recruit the RNA polymerase II CTD.
Plos Pathog., 18, 2022
4WSB
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BU of 4wsb by Molmil
Bat Influenza A polymerase with bound vRNA promoter
分子名称: Influenza A polymerase vRNA promoter 3' end, Influenza A polymerase vRNA promoter 5' end, PHOSPHATE ION, ...
著者Cusack, S, Pflug, A, Guilligay, D, Reich, S.
登録日2014-10-26
公開日2014-11-19
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Structural insight into cap-snatching and RNA synthesis by influenza polymerase.
Nature, 516, 2014
5MSG
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BU of 5msg by Molmil
Influenza B polymerase bound to vRNA promoter and capped RNA primer
分子名称: PHOSPHATE ION, Polymerase acidic protein, Polymerase basic protein 2, ...
著者Cusack, S, Guilligay, D.
登録日2017-01-04
公開日2017-02-08
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献An in vitro fluorescence based study of initiation of RNA synthesis by influenza B polymerase.
Nucleic Acids Res., 45, 2017
7ZPL
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BU of 7zpl by Molmil
Symmetric dimer of influenza A/H7N9 polymerase bound to 5' vRNA hook
分子名称: 5' vRNA, MAGNESIUM ION, Polymerase acidic protein, ...
著者Cusack, S, Kouba, T.
登録日2022-04-27
公開日2022-12-28
最終更新日2023-02-15
実験手法ELECTRON MICROSCOPY (3.12 Å)
主引用文献Direct observation of backtracking by influenza A and B polymerases upon consecutive incorporation of the nucleoside analog T1106.
Cell Rep, 42, 2023
7ZPM
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BU of 7zpm by Molmil
Influenza A/H7N9 polymerase apo-protein dimer complex
分子名称: Polymerase acidic protein, Polymerase basic protein 2, RNA-directed RNA polymerase catalytic subunit
著者Cusack, S, Kouba, T.
登録日2022-04-27
公開日2022-12-28
最終更新日2023-02-15
実験手法ELECTRON MICROSCOPY (2.81 Å)
主引用文献Direct observation of backtracking by influenza A and B polymerases upon consecutive incorporation of the nucleoside analog T1106.
Cell Rep, 42, 2023
8BDR
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BU of 8bdr by Molmil
Early transcription elongation state of influenza B/Mem polymerase backtracked due to double incoproation of nucleotide analogue T1106 and with singly incoporated T1106 at the U +1 position
分子名称: 3' vRNA, 5' vRNA, MAGNESIUM ION, ...
著者Cusack, S, Kouba, T.
登録日2022-10-19
公開日2022-12-28
最終更新日2023-02-15
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Direct observation of backtracking by influenza A and B polymerases upon consecutive incorporation of the nucleoside analog T1106.
Cell Rep, 42, 2023

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