1H3N

Leucyl-tRNA synthetase from Thermus thermophilus complexed with a sulphamoyl analogue of leucyl-adenylate

Summary for 1H3N

• Entry DOI: 10.2210/pdb1h3n/pdb
• Descriptor: LEUCYL-TRNA SYNTHETASE, LEUCINE, [(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDRO-2-FURANYL]METHYL SULFAMATE, ... (6 entities in total)
• Functional Keywords: aminoacyl-trna synthetase, class i aminoacyl-trna synthetase, atp + l-leucine + trna (leu) -> amp + ppi + l-leucyl-trna(leu), ligase
• Biological source: THERMUS THERMOPHILUS
• Total number of polymer chains: 1
• Total formula weight: 102066.65

Authors

Cusack, S.,Yaremchuk, A.,Tukalo, M. (deposition date: 2002-09-11, release date: 2002-09-27, Last modification date: 2011-07-13)

• Primary citation: Cusack, S.,Yaremchuk, A.,Tukalo, M.; The 2A Structure of Leucyl-tRNA Synthetase and its Complex with a Leucyl-Adenylate Analogue; Embo J., 19:2351-, 2000; PubMed: 10811626; DOI: 10.1093/EMBOJ/19.10.2351

Experimental method

X-RAY DIFFRACTION (2 Å)