7ZPL

Symmetric dimer of influenza A/H7N9 polymerase bound to 5' vRNA hook

Summary for 7ZPL

Entry DOI	10.2210/pdb7zpl/pdb
Related	7QTL
EMDB information	14857
Descriptor	Polymerase acidic protein, RNA-directed RNA polymerase catalytic subunit, Polymerase basic protein 2, ... (5 entities in total)
Functional Keywords	influenza, h7n9, viral rna-dependent rna polymerase, viral protein
Biological source	Influenza A virus (A/Zhejiang/DTID-ZJU01/2013(H7N9)) More
Total number of polymer chains	8
Total formula weight	520008.10
Authors	Cusack, S.,Kouba, T. (deposition date: 2022-04-27, release date: 2022-12-28, Last modification date: 2023-02-15)
Primary citation	Kouba, T.,Dubankova, A.,Drncova, P.,Donati, E.,Vidossich, P.,Speranzini, V.,Pflug, A.,Huchting, J.,Meier, C.,De Vivo, M.,Cusack, S. Direct observation of backtracking by influenza A and B polymerases upon consecutive incorporation of the nucleoside analog T1106. Cell Rep, 42:111901-111901, 2023 Cited by PubMed: 36596301 DOI: 10.1016/j.celrep.2022.111901 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.12 Å)

Structure validation