7Z4O
Influenza A/H7N9 polymerase core dimer with Pol II pSer5 CTD peptide mimic bound in site 2A
This is a non-PDB format compatible entry.
Summary for 7Z4O
| Entry DOI | 10.2210/pdb7z4o/pdb |
| Descriptor | Polymerase acidic protein, RNA-directed RNA polymerase catalytic subunit, Polymerase basic protein 2, ... (6 entities in total) |
| Functional Keywords | influenza rna-dependent rna polymerase, transcription, cap-snatching, pol ii ctd, rna binding protein |
| Biological source | Influenza A virus More |
| Total number of polymer chains | 10 |
| Total formula weight | 340915.36 |
| Authors | Cusack, S.,Pflug, A. (deposition date: 2022-03-04, release date: 2022-05-11, Last modification date: 2024-01-31) |
| Primary citation | Krischuns, T.,Isel, C.,Drncova, P.,Lukarska, M.,Pflug, A.,Paisant, S.,Navratil, V.,Cusack, S.,Naffakh, N. Type B and type A influenza polymerases have evolved distinct binding interfaces to recruit the RNA polymerase II CTD. Plos Pathog., 18:e1010328-e1010328, 2022 Cited by PubMed: 35605026DOI: 10.1371/journal.ppat.1010328 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3.412 Å) |
Structure validation
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