7Z4O

Influenza A/H7N9 polymerase core dimer with Pol II pSer5 CTD peptide mimic bound in site 2A

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	AAA, DDD	Polymerase acidic protein	polymer	517	59383.9	2	UniProt (M9TI86) Pfam (PF00603) In PDB	Influenza A virus	RNA-directed RNA polymerase subunit P2
2	BBB, EEE	RNA-directed RNA polymerase catalytic subunit	polymer	757	86496.2	2	UniProt (A0A024E3M6) Pfam (PF00602) In PDB	Influenza A virus	Polymerase basic protein 1,PB1,RNA-directed RNA polymerase subunit P1
3	CCC, FFF	Polymerase basic protein 2	polymer	147	17453.1	2	UniProt (X5F427) Pfam (PF20947) Pfam (PF20948) In PDB	Influenza A virus	RNA-directed RNA polymerase subunit P3
4	JJJ, KKK	SER-TYR-SER-PRO-THR-SEP-PRO-SER-TYR-SER	polymer	28	3216.9	2		Homo sapiens
5	UUU, VVV	RNA (5'-R(P*AP*GP*UP*AP*GP*UP*AP*AP*CP*AP*AP*G)-3')	polymer	12	3883.4	2		Influenza A virus
6	BBB, EEE	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)

Sequence modifications

AAA, DDD: 201 - 716 (UniProt: M9TI86)

PDB	External Database	Details
Met 200	-	initiating methionine

CCC, FFF: 1 - 128 (UniProt: X5F427)

PDB	External Database	Details
Ser 129	-	expression tag
Gly 130	-	expression tag
Ser 131	-	expression tag
Glu 132	-	expression tag
Asn 133	-	expression tag
Leu 134	-	expression tag
Tyr 135	-	expression tag
Phe 136	-	expression tag
Gln 137	-	expression tag
Gly 138	-	expression tag
Ser 139	-	expression tag
His 140	-	expression tag
His 141	-	expression tag
His 142	-	expression tag
His 143	-	expression tag
His 144	-	expression tag
His 145	-	expression tag
His 146	-	expression tag
His 147	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	10
	Total formula weight	340866.7
Non-Polymers*	Number of molecules	2
	Total formula weight	48.6
All*	Total formula weight	340915.4

*Water molecules are not included.