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9C4B
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BU of 9c4b by Molmil
Second BAF53a of the human TIP60 complex
Descriptor: Actin-like protein 6A
Authors:Yang, Z, Mameri, A, Florez Ariza, A.J, Cote, J, Nogales, E.
Deposit date:2024-06-03
Release date:2024-08-14
Last modified:2024-09-11
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural insights into the human NuA4/TIP60 acetyltransferase and chromatin remodeling complex.
Science, 385, 2024
9C47
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BU of 9c47 by Molmil
TRRAP module of the human TIP60 complex
Descriptor: E1A-binding protein p400, Transformation/transcription domain-associated protein
Authors:Yang, Z, Mameri, A, Florez Ariza, A.J, Cote, J, Nogales, E.
Deposit date:2024-06-03
Release date:2024-08-14
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural insights into the human NuA4/TIP60 acetyltransferase and chromatin remodeling complex.
Science, 385, 2024
9C6N
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BU of 9c6n by Molmil
ARP module of the human TIP60 complex
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin, cytoplasmic 1, ...
Authors:Yang, Z, Mameri, A, Florez Ariza, A.J, Cote, J, Nogales, E.
Deposit date:2024-06-07
Release date:2024-08-21
Last modified:2024-09-11
Method:ELECTRON MICROSCOPY (3.29 Å)
Cite:Structural insights into the human NuA4/TIP60 acetyltransferase and chromatin remodeling complex.
Science, 385, 2024
9C57
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BU of 9c57 by Molmil
Reconstituted P400 Subcomplex of the human TIP60 complex
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin, cytoplasmic 1, ...
Authors:Yang, Z, Mameri, A, Florez Ariza, A.J, Cote, J, Nogales, E.
Deposit date:2024-06-05
Release date:2024-08-21
Last modified:2024-09-11
Method:ELECTRON MICROSCOPY (2.75 Å)
Cite:Structural insights into the human NuA4/TIP60 acetyltransferase and chromatin remodeling complex.
Science, 385, 2024
9C62
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BU of 9c62 by Molmil
P400 subcomplex of the native human TIP60 complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, cytoplasmic 1, ...
Authors:Yang, Z, Mameri, A, Florez Ariza, A.J, Cote, J, Nogales, E.
Deposit date:2024-06-07
Release date:2024-08-21
Last modified:2024-09-11
Method:ELECTRON MICROSCOPY (5.28 Å)
Cite:Structural insights into the human NuA4/TIP60 acetyltransferase and chromatin remodeling complex.
Science, 385, 2024
6OIE
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BU of 6oie by Molmil
The double PHD finger (DPF) of MORF in complex with histone H3K14cr
Descriptor: Histone H3.1t peptide, Histone acetyltransferase KAT6B, ZINC ION
Authors:Klein, B.J, Kutateladze, T.G.
Deposit date:2019-04-09
Release date:2019-11-20
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.075 Å)
Cite:Histone H3K23-specific acetylation by MORF is coupled to H3K14 acylation.
Nat Commun, 10, 2019
3TOA
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BU of 3toa by Molmil
Human MOF crystal structure with active site lysine partially acetylated
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, ZINC ION, ...
Authors:Yuan, H, Ding, E.C, Marmorstein, R.
Deposit date:2011-09-04
Release date:2011-11-09
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (3.004 Å)
Cite:MYST protein acetyltransferase activity requires active site lysine autoacetylation.
Embo J., 31, 2011
3TO6
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BU of 3to6 by Molmil
Crystal structure of yeast Esa1 HAT domain complexed with H4K16CoA bisubstrate inhibitor
Descriptor: CARBOXYMETHYL COENZYME *A, Histone H4, Histone acetyltransferase ESA1
Authors:Yuan, H, Ding, E.C, Marmorstein, R.
Deposit date:2011-09-04
Release date:2011-11-09
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:MYST protein acetyltransferase activity requires active site lysine autoacetylation.
Embo J., 31, 2011
6NFX
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BU of 6nfx by Molmil
MBTD1 MBT repeats
Descriptor: GLYCEROL, MBT domain-containing protein 1,Enhancer of polycomb homolog 1, SODIUM ION, ...
Authors:Zhang, H, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2018-12-21
Release date:2019-01-30
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural Basis for EPC1-Mediated Recruitment of MBTD1 into the NuA4/TIP60 Acetyltransferase Complex.
Cell Rep, 30, 2020
8GDX
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BU of 8gdx by Molmil
Crystal structure of JADE1 PZP domain
Descriptor: GLYCEROL, Protein Jade-1, ZINC ION
Authors:Klein, B.J, Liu, J, Kutateladze, T.G.
Deposit date:2023-03-06
Release date:2024-03-13
Last modified:2024-07-31
Method:X-RAY DIFFRACTION (2.74 Å)
Cite:Guiding the HBO1 complex function through the JADE subunit.
Nat.Struct.Mol.Biol., 31, 2024
8GE0
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BU of 8ge0 by Molmil
Crystal structure of JADE1 PZP domain in complex with Histone H3
Descriptor: Histone H3.1,Protein Jade-1, ZINC ION
Authors:Klein, B.J, Liu, J, Kutateladze, T.G.
Deposit date:2023-03-06
Release date:2024-03-13
Last modified:2024-07-31
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Guiding the HBO1 complex function through the JADE subunit.
Nat.Struct.Mol.Biol., 31, 2024
4HCZ
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BU of 4hcz by Molmil
PHF1 Tudor in complex with H3K36me3
Descriptor: H3L-like histone, PHD finger protein 1
Authors:Musselman, C.A, Roy, S, Nunez, J, Kutateladze, T.G.
Deposit date:2012-10-01
Release date:2012-11-14
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Molecular basis for H3K36me3 recognition by the Tudor domain of PHF1.
Nat.Struct.Mol.Biol., 19, 2012
6AXJ
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BU of 6axj by Molmil
Crystal structure of the Yaf9 YEATS domain bound to H3K27ac
Descriptor: ALY-SER-ALA-PRO-ALA, GLYCEROL, Protein AF-9 homolog, ...
Authors:Klein, B.J, Kutateladze, T.G.
Deposit date:2017-09-06
Release date:2017-11-22
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.379 Å)
Cite:Yaf9 subunit of the NuA4 and SWR1 complexes targets histone H3K27ac through its YEATS domain.
Nucleic Acids Res., 46, 2018
5U2J
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BU of 5u2j by Molmil
MORF double PHD finger (DPF) in complex with histone H3K14bu
Descriptor: Histone H3K14bu, Histone acetyltransferase KAT6B, ZINC ION
Authors:Andrews, F.H, Klein, B.J, Kutateladze, T.G.
Deposit date:2016-11-30
Release date:2017-04-12
Last modified:2017-04-19
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Recognition of Histone H3K14 Acylation by MORF.
Structure, 25, 2017
3TO7
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BU of 3to7 by Molmil
Crystal structure of yeast Esa1 HAT domain bound to coenzyme A with active site lysine acetylated
Descriptor: CACODYLIC ACID, COENZYME A, GLYCEROL, ...
Authors:Yuan, H, Ding, E.C, Marmorstein, R.
Deposit date:2011-09-04
Release date:2011-11-09
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:MYST protein acetyltransferase activity requires active site lysine autoacetylation.
Embo J., 31, 2011
3TOB
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BU of 3tob by Molmil
Human MOF E350Q crystal structure with active site lysine partially acetylated
Descriptor: CHLORIDE ION, ZINC ION, histone acetyltransferase MYST1
Authors:Yuan, H, Ding, E.C, Marmorstein, R.
Deposit date:2011-09-04
Release date:2011-11-09
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.703 Å)
Cite:MYST protein acetyltransferase activity requires active site lysine autoacetylation.
Embo J., 31, 2011
3TO9
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BU of 3to9 by Molmil
Crystal structure of yeast Esa1 E338Q HAT domain bound to coenzyme A with active site lysine acetylated
Descriptor: 1,2-ETHANEDIOL, CACODYLIC ACID, COENZYME A, ...
Authors:Yuan, H, Ding, E.C, Marmorstein, R.
Deposit date:2011-09-04
Release date:2011-11-09
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:MYST protein acetyltransferase activity requires active site lysine autoacetylation.
Embo J., 31, 2011
5Y81
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BU of 5y81 by Molmil
NuA4 TEEAA sub-complex
Descriptor: Actin, Actin-related protein 4, Chromatin modification-related protein EAF1, ...
Authors:Wang, X, Cai, G.
Deposit date:2017-08-18
Release date:2018-04-18
Last modified:2024-11-20
Method:ELECTRON MICROSCOPY (4.7 Å)
Cite:Architecture of the Saccharomyces cerevisiae NuA4/TIP60 complex
Nat Commun, 9, 2018
3C6W
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BU of 3c6w by Molmil
Crystal structure of the ING5 PHD finger in complex with H3K4me3 peptide
Descriptor: H3K4me3 histone peptide, Inhibitor of growth protein 5, ZINC ION
Authors:Champagne, K.S, Pena, P.V, Johnson, K, Kutateladze, T.G.
Deposit date:2008-02-05
Release date:2008-06-03
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:The crystal structure of the ING5 PHD finger in complex with an H3K4me3 histone peptide.
Proteins, 72, 2008
7TUQ
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BU of 7tuq by Molmil
Crystal structure of BRD4 bromodomain 1 in complex with monoacetylated SARS-CoV-2 E
Descriptor: Bromodomain-containing protein 4, Envelope small membrane protein
Authors:Vann, K.R, Kutateladze, T.G.
Deposit date:2022-02-03
Release date:2022-07-06
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2.68 Å)
Cite:Binding of the SARS-CoV-2 envelope E protein to human BRD4 is essential for infection.
Structure, 30, 2022
7TV0
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BU of 7tv0 by Molmil
Crystal structure of BRD4 bromodomain 1 in complex with dual-acetylated SARS-CoV-2 E
Descriptor: Bromodomain-containing protein 4, Envelope small membrane protein
Authors:Vann, K.R, Holt, T.A, Kutateladze, T.G.
Deposit date:2022-02-03
Release date:2022-07-06
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Binding of the SARS-CoV-2 envelope E protein to human BRD4 is essential for infection.
Structure, 30, 2022
9ATN
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BU of 9atn by Molmil
NMR structure of the MLL4 PHD2/3 fingers in complex with ASXL2
Descriptor: Histone-lysine N-methyltransferase 2D, Polycomb group protein ASXL2, ZINC ION
Authors:Zhang, Y, Zandian, M, Kutateladze, T.
Deposit date:2024-02-27
Release date:2024-06-19
Method:SOLUTION NMR
Cite:ASXLs binding to the PHD2/3 fingers of MLL4 provides a mechanism for the recruitment of BAP1 to active enhancers.
Nat Commun, 15, 2024
8E4V
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BU of 8e4v by Molmil
Solution structure of the WH domain of MORF
Descriptor: Isoform 3 of Histone acetyltransferase KAT6B
Authors:Zhang, Y, Kutateladze, T.G.
Deposit date:2022-08-19
Release date:2023-05-10
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:MORF and MOZ acetyltransferases target unmethylated CpG islands through the winged helix domain.
Nat Commun, 14, 2023
6U04
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BU of 6u04 by Molmil
Crystal structure of human BRPF1 PZP bound to histone H3 tail
Descriptor: Histone H3.3,BRPF1, Peregrin, PRASEODYMIUM ION, ...
Authors:Klein, B.J, Kutateladze, T.G.
Deposit date:2019-08-13
Release date:2019-11-27
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Molecular Basis for the PZP Domain of BRPF1 Association with Chromatin.
Structure, 28, 2020
5ERC
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BU of 5erc by Molmil
X-ray crystal structure of BRPF1 PZP domain
Descriptor: CALCIUM ION, Peregrin, ZINC ION
Authors:Klein, B.J, Andrews, F.H, Kutateladze, T.G.
Deposit date:2015-11-13
Release date:2015-12-30
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Bivalent interaction of the PZP domain of BRPF1 with the nucleosome impacts chromatin dynamics and acetylation.
Nucleic Acids Res., 44, 2016

 

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PDB entries from 2024-11-20

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