6T90
| OCT4-SOX2-bound nucleosome - SHL-6 | 分子名称: | DNA (146-MER), Green fluorescent protein,POU domain, class 5, ... | 著者 | Michael, A.K, Kempf, G, Cavadini, S, Bunker, R.D, Thoma, N.H. | 登録日 | 2019-10-25 | 公開日 | 2020-05-06 | 最終更新日 | 2020-07-08 | 実験手法 | ELECTRON MICROSCOPY (3.05 Å) | 主引用文献 | Mechanisms of OCT4-SOX2 motif readout on nucleosomes. Science, 368, 2020
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6T93
| Nucleosome with OCT4-SOX2 motif at SHL-6 | 分子名称: | DNA (153-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | 著者 | Michael, A.K, Kempf, G, Cavadini, S, Bunker, R.D, Thoma, N.H. | 登録日 | 2019-10-25 | 公開日 | 2020-05-06 | 最終更新日 | 2020-07-08 | 実験手法 | ELECTRON MICROSCOPY (3.49 Å) | 主引用文献 | Mechanisms of OCT4-SOX2 motif readout on nucleosomes. Science, 368, 2020
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8P83
| Cryo-EM structure of full-length human UBR5 (homotetramer) | 分子名称: | E3 ubiquitin-protein ligase UBR5 | 著者 | Aguirre, J.D, Kater, L, Kempf, G, Cavadini, S, Thoma, N.H. | 登録日 | 2023-05-31 | 公開日 | 2023-06-14 | 最終更新日 | 2023-08-16 | 実験手法 | ELECTRON MICROSCOPY (3.87 Å) | 主引用文献 | UBR5 forms ligand-dependent complexes on chromatin to regulate nuclear hormone receptor stability. Mol.Cell, 83, 2023
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8OSL
| Cryo-EM structure of CLOCK-BMAL1 bound to the native Por enhancer nucleosome (map 2, additional 3D classification and flexible refinement) | 分子名称: | Basic helix-loop-helix ARNT-like protein 1, Circadian locomoter output cycles protein kaput, DNA (147-MER), ... | 著者 | Michael, A.K, Stoos, L, Kempf, G, Cavadini, S, Thoma, N. | 登録日 | 2023-04-19 | 公開日 | 2023-05-24 | 最終更新日 | 2023-07-26 | 実験手法 | ELECTRON MICROSCOPY (4.9 Å) | 主引用文献 | Cooperation between bHLH transcription factors and histones for DNA access. Nature, 619, 2023
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8OTS
| OCT4 and MYC-MAX co-bound to a nucleosome | 分子名称: | DNA (127-MER), Green fluorescent protein,POU domain, class 5, ... | 著者 | Michael, A.K, Stoos, L, Kempf, G, Cavadini, S, Thoma, N. | 登録日 | 2023-04-21 | 公開日 | 2023-05-24 | 最終更新日 | 2023-07-26 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Cooperation between bHLH transcription factors and histones for DNA access. Nature, 619, 2023
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8OTT
| MYC-MAX bound to a nucleosome at SHL+5.8 | 分子名称: | DNA (144-MER), Histone H2A type 1-B/E, Histone H2A type 1-K, ... | 著者 | Stoos, L, Michael, A.K, Kempf, G, Kater, L, Cavadini, S, Thoma, N. | 登録日 | 2023-04-21 | 公開日 | 2023-05-24 | 最終更新日 | 2023-09-06 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Cooperation between bHLH transcription factors and histones for DNA access. Nature, 619, 2023
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8OSK
| Cryo-EM structure of CLOCK-BMAL1 bound to a nucleosomal E-box at position SHL+5.8 (composite map) | 分子名称: | Basic helix-loop-helix ARNT-like protein 1, Circadian locomoter output cycles protein kaput, DNA (124-MER), ... | 著者 | Stoos, L, Michael, A.K, Kempf, G, Cavadini, S, Thoma, N.H. | 登録日 | 2023-04-19 | 公開日 | 2023-05-24 | 最終更新日 | 2023-07-26 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Cooperation between bHLH transcription factors and histones for DNA access. Nature, 619, 2023
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8OSJ
| Cryo-EM structure of CLOCK-BMAL1 bound to a nucleosomal E-box at position SHL-6.2 (DNA conformation 1) | 分子名称: | Basic helix-loop-helix ARNT-like protein 1, Circadian locomoter output cycles protein kaput, DNA (124-MER), ... | 著者 | Michael, A.K, Stoos, L, Kempf, G, Cavadini, S, Thoma, N.H. | 登録日 | 2023-04-19 | 公開日 | 2023-05-24 | 最終更新日 | 2023-07-26 | 実験手法 | ELECTRON MICROSCOPY (6.2 Å) | 主引用文献 | Cooperation between bHLH transcription factors and histones for DNA access. Nature, 619, 2023
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7Q3E
| Structure of the mouse CPLANE-RSG1 complex | 分子名称: | Ciliogenesis and planar polarity effector 2, GUANOSINE-5'-TRIPHOSPHATE, Protein fuzzy homolog, ... | 著者 | Langousis, G, Cavadini, S, Kempf, G, Matthias, P. | 登録日 | 2021-10-27 | 公開日 | 2022-04-06 | 最終更新日 | 2022-04-27 | 実験手法 | ELECTRON MICROSCOPY (3.35 Å) | 主引用文献 | Structure of the ciliogenesis-associated CPLANE complex. Sci Adv, 8, 2022
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7Q3D
| Structure of the human CPLANE complex | 分子名称: | Protein fuzzy homolog, Protein inturned, WD repeat-containing and planar cell polarity effector protein fritz homolog | 著者 | Langousis, G, Cavadini, S, Kempf, G, Matthias, P. | 登録日 | 2021-10-27 | 公開日 | 2022-04-06 | 最終更新日 | 2022-04-27 | 実験手法 | ELECTRON MICROSCOPY (3.35 Å) | 主引用文献 | Structure of the ciliogenesis-associated CPLANE complex. Sci Adv, 8, 2022
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8AJM
| Structure of human DDB1-DCAF12 in complex with the C-terminus of CCT5 | 分子名称: | DDB1- and CUL4-associated factor 12, DNA damage-binding protein 1, T-complex protein 1 subunit epsilon | 著者 | Pla-Prats, C, Cavadini, S, Kempf, G, Thoma, N.H. | 登録日 | 2022-07-28 | 公開日 | 2022-11-09 | 最終更新日 | 2023-05-24 | 実験手法 | ELECTRON MICROSCOPY (2.83 Å) | 主引用文献 | Recognition of the CCT5 di-Glu degron by CRL4 DCAF12 is dependent on TRiC assembly. Embo J., 42, 2023
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8AJN
| Structure of the human DDB1-DCAF12 complex | 分子名称: | DDB1- and CUL4-associated factor 12, DNA damage-binding protein 1 | 著者 | Pla-Prats, C, Cavadini, S, Kempf, G, Thoma, N.H. | 登録日 | 2022-07-28 | 公開日 | 2022-11-09 | 最終更新日 | 2023-05-24 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Recognition of the CCT5 di-Glu degron by CRL4 DCAF12 is dependent on TRiC assembly. Embo J., 42, 2023
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8AJO
| Negative-stain electron microscopy structure of DDB1-DCAF12-CCT5 | 分子名称: | DDB1- and CUL4-associated factor 12, DNA damage-binding protein 1, T-complex protein 1 subunit epsilon | 著者 | Pla-Prats, C, Cavadini, S, Kempf, G, Thoma, N.H. | 登録日 | 2022-07-28 | 公開日 | 2022-11-09 | 最終更新日 | 2023-05-24 | 実験手法 | ELECTRON MICROSCOPY (30.6 Å) | 主引用文献 | Recognition of the CCT5 di-Glu degron by CRL4 DCAF12 is dependent on TRiC assembly. Embo J., 42, 2023
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6YOV
| OCT4-SOX2-bound nucleosome - SHL+6 | 分子名称: | DNA (142-MER), Green fluorescent protein,POU domain, class 5, ... | 著者 | Michael, A.K, Kempf, G, Cavadini, S, Bunker, R.D, Thoma, N.H. | 登録日 | 2020-04-15 | 公開日 | 2020-05-06 | 最終更新日 | 2020-07-08 | 実験手法 | ELECTRON MICROSCOPY (3.42 Å) | 主引用文献 | Mechanisms of OCT4-SOX2 motif readout on nucleosomes. Science, 368, 2020
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6Y5D
| Structure of human cGAS (K394E) bound to the nucleosome | 分子名称: | Cyclic GMP-AMP synthase, DNA (153-MER), Histone H2A type 2-A, ... | 著者 | Pathare, G.R, Cavadini, S, Kempf, G, Thoma, N.H. | 登録日 | 2020-02-25 | 公開日 | 2020-09-23 | 最終更新日 | 2020-12-09 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Structural mechanism of cGAS inhibition by the nucleosome. Nature, 587, 2020
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7O2W
| Structure of the C9orf72-SMCR8 complex | 分子名称: | Guanine nucleotide exchange protein SMCR8,Guanine nucleotide exchange protein SMCR8,Maltose/maltodextrin-binding periplasmic protein, Ubiquitin-like protein SMT3,Guanine nucleotide exchange C9orf72 | 著者 | Noerpel, J, Cavadini, S, Schenk, A.D, Graff-Meyer, A, Chao, J, Bhaskar, V. | 登録日 | 2021-03-31 | 公開日 | 2021-07-21 | 最終更新日 | 2022-02-02 | 実験手法 | ELECTRON MICROSCOPY | 主引用文献 | Structure of the human C9orf72-SMCR8 complex reveals a multivalent protein interaction architecture. Plos Biol., 19, 2021
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7OKQ
| Cryo-EM Structure of the DDB1-DCAF1-CUL4A-RBX1 Complex | 分子名称: | Cullin-4A, DDB1- and CUL4-associated factor 1, DNA damage-binding protein 1, ... | 著者 | Mohamed, W.I, Schenk, A.D, Kempf, G, Cavadini, S, Thoma, N.H. | 登録日 | 2021-05-18 | 公開日 | 2021-10-13 | 最終更新日 | 2021-12-01 | 実験手法 | ELECTRON MICROSCOPY (8.4 Å) | 主引用文献 | The CRL4 DCAF1 cullin-RING ubiquitin ligase is activated following a switch in oligomerization state. Embo J., 40, 2021
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6Y5E
| Structure of human cGAS (K394E) bound to the nucleosome (focused refinement of cGAS-NCP subcomplex) | 分子名称: | Cyclic GMP-AMP synthase, DNA (153-MER), Histone H2A type 2-C, ... | 著者 | Pathare, G.R, Cavadini, S, Kempf, G, Thoma, N.H. | 登録日 | 2020-02-25 | 公開日 | 2020-09-23 | 最終更新日 | 2020-12-09 | 実験手法 | ELECTRON MICROSCOPY (3.15 Å) | 主引用文献 | Structural mechanism of cGAS inhibition by the nucleosome. Nature, 587, 2020
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6R8Z
| Cryo-EM structure of NCP_THF2(-1)-UV-DDB | 分子名称: | DNA damage-binding protein 1, DNA damage-binding protein 2, Histone H2A type 1-B/E, ... | 著者 | Matsumoto, S, Cavadini, S, Bunker, R.D, Thoma, N.H. | 登録日 | 2019-04-02 | 公開日 | 2019-06-12 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | DNA damage detection in nucleosomes involves DNA register shifting. Nature, 571, 2019
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6R94
| Cryo-EM structure of NCP_THF2(-3) | 分子名称: | Histone H2A type 1-B/E, Histone H2B type 1-J, Histone H3.1, ... | 著者 | Matsumoto, S, Cavadini, S, Bunker, R.D, Thoma, N.H. | 登録日 | 2019-04-02 | 公開日 | 2019-06-12 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | DNA damage detection in nucleosomes involves DNA register shifting. Nature, 571, 2019
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6R91
| Cryo-EM structure of NCP_THF2(-3)-UV-DDB | 分子名称: | DNA damage-binding protein 1, DNA damage-binding protein 2, Histone H2A type 1-B/E, ... | 著者 | Matsumoto, S, Cavadini, S, Bunker, R.D, Thoma, N.H. | 登録日 | 2019-04-02 | 公開日 | 2019-06-12 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | DNA damage detection in nucleosomes involves DNA register shifting. Nature, 571, 2019
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6R8Y
| Cryo-EM structure of NCP-6-4PP(-1)-UV-DDB | 分子名称: | DNA damage-binding protein 1, DNA damage-binding protein 2, Histone H2A type 1-B/E, ... | 著者 | Matsumoto, S, Cavadini, S, Bunker, R.D, Thoma, N.H. | 登録日 | 2019-04-02 | 公開日 | 2019-06-12 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | DNA damage detection in nucleosomes involves DNA register shifting. Nature, 571, 2019
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6R93
| Cryo-EM structure of NCP-6-4PP | 分子名称: | Histone H2A type 1-B/E, Histone H2B type 1-J, Histone H3.1, ... | 著者 | Matsumoto, S, Cavadini, S, Bunker, R.D, Thoma, N.H. | 登録日 | 2019-04-02 | 公開日 | 2019-06-12 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | DNA damage detection in nucleosomes involves DNA register shifting. Nature, 571, 2019
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6R92
| Cryo-EM structure of NCP-THF2(+1)-UV-DDB class B | 分子名称: | DNA damage-binding protein 1,DNA damage-binding protein 1, DNA damage-binding protein 2, Histone H2A type 1-B/E, ... | 著者 | Matsumoto, S, Cavadini, S, Bunker, R.D, Thoma, N.H. | 登録日 | 2019-04-02 | 公開日 | 2019-06-12 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (4.8 Å) | 主引用文献 | DNA damage detection in nucleosomes involves DNA register shifting. Nature, 571, 2019
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6R90
| Cryo-EM structure of NCP-THF2(+1)-UV-DDB class A | 分子名称: | DNA damage-binding protein 1, DNA damage-binding protein 2, Histone H2A type 1-B/E, ... | 著者 | Matsumoto, S, Cavadini, S, Bunker, R.D, Thoma, N.H. | 登録日 | 2019-04-02 | 公開日 | 2019-06-12 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | DNA damage detection in nucleosomes involves DNA register shifting. Nature, 571, 2019
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