8AJM

Structure of human DDB1-DCAF12 in complex with the C-terminus of CCT5

Summary for 8AJM

• Entry DOI: 10.2210/pdb8ajm/pdb
• EMDB information: 15484
• Descriptor: DNA damage-binding protein 1, DDB1- and CUL4-associated factor 12, T-complex protein 1 subunit epsilon (3 entities in total)
• Functional Keywords: ubiquitin, e3, tric, chaperonin, ligase
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 245594.26

Authors

Pla-Prats, C.,Cavadini, S.,Kempf, G.,Thoma, N.H. (deposition date: 2022-07-28, release date: 2022-11-09, Last modification date: 2023-05-24)

• Primary citation: Pla-Prats, C.,Cavadini, S.,Kempf, G.,Thoma, N.H.; Recognition of the CCT5 di-Glu degron by CRL4 DCAF12 is dependent on TRiC assembly.; Embo J., 42:e112253-e112253, 2023; PubMed: 36715408; DOI: 10.15252/embj.2022112253

Experimental method

ELECTRON MICROSCOPY (2.83 Å)