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6ZMO
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BU of 6zmo by Molmil
SARS-CoV-2 Nsp1 bound to the human LYAR-80S-eEF1a ribosome complex
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
Authors:Thoms, M, Buschauer, R, Ameismeier, M, Denk, T, Kratzat, H, Mackens-Kiani, T, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R.
Deposit date:2020-07-03
Release date:2020-08-19
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2.
Science, 369, 2020
6ZM7
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BU of 6zm7 by Molmil
SARS-CoV-2 Nsp1 bound to the human CCDC124-80S-EBP1 ribosome complex
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
Authors:Thoms, M, Buschauer, R, Ameismeier, M, Denk, T, Kratzat, H, Mackens-Kiani, T, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R.
Deposit date:2020-07-01
Release date:2020-07-29
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2.
Science, 369, 2020
6ZMT
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BU of 6zmt by Molmil
SARS-CoV-2 Nsp1 bound to a pre-40S-like ribosome complex
Descriptor: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
Authors:Thoms, M, Buschauer, R, Ameismeier, M, Denk, T, Kratzat, H, Mackens-Kiani, T, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R.
Deposit date:2020-07-03
Release date:2020-08-19
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2.
Science, 369, 2020
6ZME
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BU of 6zme by Molmil
SARS-CoV-2 Nsp1 bound to the human CCDC124-80S-eERF1 ribosome complex
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
Authors:Thoms, M, Buschauer, R, Ameismeier, M, Denk, T, Kratzat, H, Mackens-Kiani, T, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R.
Deposit date:2020-07-02
Release date:2020-08-12
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2.
Science, 369, 2020
6ZLW
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BU of 6zlw by Molmil
SARS-CoV-2 Nsp1 bound to the human 40S ribosomal subunit
Descriptor: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
Authors:Thoms, M, Buschauer, R, Ameismeier, M, Denk, T, Kratzat, H, Mackens-Kiani, T, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R.
Deposit date:2020-07-01
Release date:2020-07-29
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2.
Science, 369, 2020
6ZN5
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BU of 6zn5 by Molmil
SARS-CoV-2 Nsp1 bound to a pre-40S-like ribosome complex - state 2
Descriptor: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
Authors:Thoms, M, Buschauer, R, Ameismeier, M, Denk, T, Kratzat, H, Mackens-Kiani, T, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R.
Deposit date:2020-07-06
Release date:2020-07-29
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2.
Science, 369, 2020
6ZP4
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BU of 6zp4 by Molmil
SARS-CoV-2 Nsp1 bound to a human 43S preinitiation ribosome complex - state 2
Descriptor: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
Authors:Thoms, M, Buschauer, R, Ameismeier, M, Denk, T, Kratzat, H, Mackens-Kiani, T, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R.
Deposit date:2020-07-08
Release date:2020-07-29
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2.
Science, 369, 2020
6ZON
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BU of 6zon by Molmil
SARS-CoV-2 Nsp1 bound to a human 43S preinitiation ribosome complex - state 1
Descriptor: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
Authors:Thoms, M, Buschauer, R, Ameismeier, M, Denk, T, Kratzat, H, Mackens-Kiani, T, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R.
Deposit date:2020-07-07
Release date:2020-07-29
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2.
Science, 369, 2020
7ZW0
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BU of 7zw0 by Molmil
FAP-80S Complex - Rotated state
Descriptor: 18S ribosomal RNA (RDN18-1), 25S ribosomal RNA (RDN25-1), 40S ribosomal protein S0-A, ...
Authors:Ikeuchi, K, Buschauer, R, Berninghausen, O, Becker, T, Beckmann, R.
Deposit date:2022-05-17
Release date:2022-10-05
Method:ELECTRON MICROSCOPY (2.4 Å)
Cite:Sensing of individual stalled 80S ribosomes by Fap1 for nonfunctional rRNA turnover.
Mol.Cell, 82, 2022
8AAF
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BU of 8aaf by Molmil
Yeast RQC complex in state G
Descriptor: 25S rRNA, 5.8S rRNA, 5S rRNA, ...
Authors:Tesina, P, Buschauer, R, Beckmann, R.
Deposit date:2022-07-01
Release date:2023-03-08
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Molecular basis of eIF5A-dependent CAT tailing in eukaryotic ribosome-associated quality control.
Mol.Cell, 83, 2023
8AGV
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BU of 8agv by Molmil
Yeast RQC complex in state H
Descriptor: 25S rRNA, 5.8S rRNA, 5S rRNA, ...
Authors:Tesina, P, Buschauer, R, Beckmann, R.
Deposit date:2022-07-20
Release date:2023-03-08
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Molecular basis of eIF5A-dependent CAT tailing in eukaryotic ribosome-associated quality control.
Mol.Cell, 83, 2023
8AGZ
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BU of 8agz by Molmil
Yeast RQC complex in state with the RING domain of Ltn1 in the OUT position
Descriptor: 25S rRNA, 5.8S rRNA, 5S rRNA, ...
Authors:Tesina, P, Buschauer, R, Beckmann, R.
Deposit date:2022-07-20
Release date:2023-03-08
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Molecular basis of eIF5A-dependent CAT tailing in eukaryotic ribosome-associated quality control.
Mol.Cell, 83, 2023
8AGW
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BU of 8agw by Molmil
Yeast RQC complex in state D
Descriptor: 25S rRNA, 5.8S rRNA, 5S rRNA, ...
Authors:Tesina, P, Buschauer, R, Beckmann, R.
Deposit date:2022-07-20
Release date:2023-03-08
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Molecular basis of eIF5A-dependent CAT tailing in eukaryotic ribosome-associated quality control.
Mol.Cell, 83, 2023
8AGU
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BU of 8agu by Molmil
Yeast RQC complex in state E
Descriptor: 25S rRNA, 5.8S rRNA, 5S rRNA, ...
Authors:Tesina, P, Buschauer, R, Beckmann, R.
Deposit date:2022-07-20
Release date:2023-03-08
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Molecular basis of eIF5A-dependent CAT tailing in eukaryotic ribosome-associated quality control.
Mol.Cell, 83, 2023
8AGX
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BU of 8agx by Molmil
Yeast RQC complex in state with the RING domain of Ltn1 in the IN position
Descriptor: 25S rRNA, 5.8S rRNA, 5S rRNA, ...
Authors:Tesina, P, Buschauer, R, Beckmann, R.
Deposit date:2022-07-20
Release date:2023-03-08
Method:ELECTRON MICROSCOPY (2.4 Å)
Cite:Molecular basis of eIF5A-dependent CAT tailing in eukaryotic ribosome-associated quality control.
Mol.Cell, 83, 2023
8AGT
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BU of 8agt by Molmil
Yeast RQC complex in state F
Descriptor: 25S rRNA, 5.8S rRNA, 5S rRNA, ...
Authors:Tesina, P, Buschauer, R, Beckmann, R.
Deposit date:2022-07-20
Release date:2023-03-08
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Molecular basis of eIF5A-dependent CAT tailing in eukaryotic ribosome-associated quality control.
Mol.Cell, 83, 2023
8BGU
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BU of 8bgu by Molmil
human MDM2-5S RNP
Descriptor: 5S rRNA, 60S ribosomal protein L11, 60S ribosomal protein L5, ...
Authors:Castillo, N, Thoms, M, Flemming, D, Hammaren, H.M, Buschauer, R, Ameismeier, M, Bassler, J, Beck, M, Beckmann, R, Hurt, E.
Deposit date:2022-10-28
Release date:2023-06-14
Last modified:2023-08-30
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structure of nascent 5S RNPs at the crossroad between ribosome assembly and MDM2-p53 pathways.
Nat.Struct.Mol.Biol., 30, 2023
8CAS
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BU of 8cas by Molmil
Cryo-EM structure of native Otu2-bound ubiquitinated 48S initiation complex (partial)
Descriptor: 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
Authors:Ikeuchi, K, Buschauer, R, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R.
Deposit date:2023-01-24
Release date:2023-05-24
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Molecular basis for recognition and deubiquitination of 40S ribosomes by Otu2.
Nat Commun, 14, 2023
8C83
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BU of 8c83 by Molmil
Cryo-EM structure of in vitro reconstituted Otu2-bound Ub-40S complex
Descriptor: 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S11-A, ...
Authors:Ikeuchi, K, Buschauer, R, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R.
Deposit date:2023-01-18
Release date:2023-05-24
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Molecular basis for recognition and deubiquitination of 40S ribosomes by Otu2.
Nat Commun, 14, 2023
8CBJ
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BU of 8cbj by Molmil
Cryo-EM structure of Otu2-bound cytoplasmic pre-40S ribosome biogenesis complex
Descriptor: 20S pre-ribosomal RNA, 20S-pre-rRNA D-site endonuclease NOB1, 40S ribosomal protein S0-A, ...
Authors:Ikeuchi, K, Buschauer, R, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R.
Deposit date:2023-01-25
Release date:2023-05-24
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Molecular basis for recognition and deubiquitination of 40S ribosomes by Otu2.
Nat Commun, 14, 2023
8CAH
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BU of 8cah by Molmil
Cryo-EM structure of native Otu2-bound ubiquitinated 43S pre-initiation complex
Descriptor: 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
Authors:Ikeuchi, K, Buschauer, R, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R.
Deposit date:2023-01-24
Release date:2023-05-24
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Molecular basis for recognition and deubiquitination of 40S ribosomes by Otu2.
Nat Commun, 14, 2023
7OJ0
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BU of 7oj0 by Molmil
Cryo-EM structure of 70S ribosome stalled with TnaC peptide and RF2
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Su, T, Kudva, R, Becker, T, Berninghausen, O, Heijne, G, Cheng, J, Beckmann, R.
Deposit date:2021-05-13
Release date:2021-09-15
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural basis of l-tryptophan-dependent inhibition of release factor 2 by the TnaC arrest peptide.
Nucleic Acids Res., 49, 2021
7OIZ
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BU of 7oiz by Molmil
Cryo-EM structure of 70S ribosome stalled with TnaC peptide
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Su, T, Kudva, R, Becker, T, Berninghausen, O, Heijne, G, Cheng, J, Beckmann, R.
Deposit date:2021-05-13
Release date:2021-09-15
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural basis of l-tryptophan-dependent inhibition of release factor 2 by the TnaC arrest peptide.
Nucleic Acids Res., 49, 2021
6YXJ
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BU of 6yxj by Molmil
Crystal structure of SARS-CoV macrodomain II in complex with human Paip1
Descriptor: Non-structural protein 3, Polyadenylate-binding protein-interacting protein 1
Authors:Lei, J, Hilgenfeld, R.
Deposit date:2020-05-02
Release date:2021-03-17
Last modified:2021-09-29
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:The SARS-unique domain (SUD) of SARS-CoV and SARS-CoV-2 interacts with human Paip1 to enhance viral RNA translation.
Embo J., 40, 2021
6XR4
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BU of 6xr4 by Molmil
Integrative in situ structure of Parkinsons disease-linked human LRRK2
Descriptor: Leucine-rich repeat serine/threonine-protein kinase 2
Authors:Villa, E, Lasker, K, Audagnotto, M.
Deposit date:2020-07-10
Release date:2020-08-19
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (14 Å)
Cite:The In Situ Structure of Parkinson's Disease-Linked LRRK2.
Cell, 182, 2020

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