6YXJ
Crystal structure of SARS-CoV macrodomain II in complex with human Paip1
Summary for 6YXJ
| Entry DOI | 10.2210/pdb6yxj/pdb |
| Descriptor | Non-structural protein 3, Polyadenylate-binding protein-interacting protein 1 (2 entities in total) |
| Functional Keywords | coronavirus, virus-host interaction, macrodomain fold, heat repeats., viral protein |
| Biological source | Severe acute respiratory syndrome coronavirus (SARS-CoV) More |
| Total number of polymer chains | 2 |
| Total formula weight | 42248.32 |
| Authors | Lei, J.,Hilgenfeld, R. (deposition date: 2020-05-02, release date: 2021-03-17, Last modification date: 2021-09-29) |
| Primary citation | Lei, J.,Ma-Lauer, Y.,Han, Y.,Thoms, M.,Buschauer, R.,Jores, J.,Thiel, V.,Beckmann, R.,Deng, W.,Leonhardt, H.,Hilgenfeld, R.,von Brunn, A. The SARS-unique domain (SUD) of SARS-CoV and SARS-CoV-2 interacts with human Paip1 to enhance viral RNA translation. Embo J., 40:e102277-e102277, 2021 Cited by PubMed: 33876849DOI: 10.15252/embj.2019102277 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3.5 Å) |
Structure validation
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