6YXJ

Crystal structure of SARS-CoV macrodomain II in complex with human Paip1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Non-structural protein 3	polymer	142	15594.0	1	UniProt (P0C6U8)	Severe acute respiratory syndrome coronavirus (SARS-CoV)	nsp3,PL2-PRO,Papain-like proteinase,PL-PRO
2	B (B)	Polyadenylate-binding protein-interacting protein 1	polymer	236	26654.3	1	UniProt (Q9H074) Pfam (PF02854)	Homo sapiens (Human)	Poly(A)-binding protein-interacting protein 1

Sequence modifications

A: 389 - 526 (UniProt: P0C6U8)

PDB	External Database	Details
Gly 385	-	expression tag
Ser 386	-	expression tag
His 387	-	expression tag
Met 388	-	expression tag

B: 78 - 296 (UniProt: Q9H074)

PDB	External Database	Details
Gly 61	-	expression tag
Ser 62	-	expression tag
His 63	-	expression tag
Met 64	-	expression tag
Ala 65	-	expression tag
Ser 66	-	expression tag
Met 67	-	expression tag
Thr 68	-	expression tag
Gly 69	-	expression tag
Gly 70	-	expression tag
Gln 71	-	expression tag
Gln 72	-	expression tag
Met 73	-	expression tag
Gly 74	-	expression tag
Arg 75	-	expression tag
Gly 76	-	expression tag
Ser 77	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	42248.3
All*	Total formula weight	42248.3

*Water molecules are not included.