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1EBM
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BU of 1ebm by Molmil
CRYSTAL STRUCTURE OF THE HUMAN 8-OXOGUANINE GLYCOSYLASE (HOGG1) BOUND TO A SUBSTRATE OLIGONUCLEOTIDE
分子名称: 8-OXOGUANINE DNA GLYCOSYLASE, CALCIUM ION, DNA (5'-D(*GP*CP*GP*TP*CP*CP*AP*(8OG)P*GP*TP*CP*TP*AP*CP*C)-3'), ...
著者Bruner, S.D, Norman, D.P, Verdine, G.L.
登録日2000-01-24
公開日2000-03-20
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural basis for recognition and repair of the endogenous mutagen 8-oxoguanine in DNA.
Nature, 403, 2000
1JMK
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BU of 1jmk by Molmil
Structural Basis for the Cyclization of the Lipopeptide Antibiotic Surfactin by the Thioesterase Domain SrfTE
分子名称: SULFATE ION, Surfactin Synthetase
著者Bruner, S.D, Weber, T, Kohli, R.M, Schwarzer, D, Marahiel, M.A, Walsh, C.T, Stubbs, M.T.
登録日2001-07-18
公開日2002-03-27
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.71 Å)
主引用文献Structural basis for the cyclization of the lipopeptide antibiotic surfactin by the thioesterase domain SrfTE.
Structure, 10, 2002
6E97
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BU of 6e97 by Molmil
Crystal structure of the aryl acid adenylating enzyme FscC from Fuscachelin NRPS in complex with DHB-adenylate
分子名称: 2,3-dihydroxybenzoate-AMP ligase, 5'-O-[(S)-[(2,3-dihydroxybenzene-1-carbonyl)oxy](hydroxy)phosphoryl]adenosine, GLYCEROL, ...
著者Bruner, S.D, Zagulyaeva, A.A.
登録日2018-07-31
公開日2019-08-21
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Implication of MbtH-like proteins in crystallization of the independent NRPS A domains. Crystal structure of FscC: supporting rationale for revised mechanism of freestanding aryl acid adenylating enzymes
To Be Published
6E8O
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BU of 6e8o by Molmil
Crystal structure of aryl acid adenylating enzyme FscC from Fuscachelin NRPS in complex with AMP
分子名称: 2,3-dihydroxybenzoate-AMP ligase, ADENOSINE MONOPHOSPHATE, GLYCEROL, ...
著者Bruner, S.D, Zagulyaeva, A.A.
登録日2018-07-30
公開日2019-08-21
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Implication of MbtH-like proteins in crystallization of the independent NRPS A domains. Crystal structure of FscC: supporting rationale for revised mechanism of freestanding aryl acid adenylating enzymes
To Be Published
6EBY
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BU of 6eby by Molmil
Crystal structure of the MbtH-like protein FscK bound to the interface forming region of FscH adenylation domain from Thermobifida fusca
分子名称: Amino acid adenylation, Conserved protein MbtH
著者Bruner, S.D, Zagulyaeva, A.A.
登録日2018-08-07
公開日2019-08-21
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Comprehensive analysis of protein-protein interactions between MbtH-like protein FscK and adenylation domains in nonribosomal biosynthesis of Fuscachelins.
To Be Published
6EA3
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BU of 6ea3 by Molmil
Thermobifida fusca FscH adenylation domain complexed with MbtH-like protein FscK and Ser-AMP
分子名称: MbtH-like protein, SERYL ADENYLATE, adenylation domain of Fuscachelin synthetase component H
著者Bruner, S.D, Zagulyaeva, A.A.
登録日2018-08-02
公開日2019-08-07
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Comprehensive analysis of protein-protein interactions between MbtH-like protein FscK and adenylation domains in nonribosomal biosynthesis of Fuscachelins.
To Be Published
2NP9
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BU of 2np9 by Molmil
Crystal structure of a dioxygenase in the Crotonase superfamily
分子名称: DpgC, OXYGEN MOLECULE, [(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-4-HYDROXY-3-(PHOSPHONOOXY)TETRAHYDROFURAN-2-YL]METHYL (3R)-4-({3-[(2-{[(3,5-DIHYDROXYPHENYL)ACETYL]AMINO}ETHYL)AMINO]-3-OXOPROPYL}AMINO)-3-HYDROXY-2,2-DIMETHYL-4-OXOBUTYL DIHYDROGEN DIPHOSPHATE
著者Bruner, S.D, Widboom, P.F, Fielding, E.N.
登録日2006-10-26
公開日2007-05-22
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Structural basis for cofactor-independent dioxygenation in vancomycin biosynthesis.
Nature, 447, 2007
8ES6
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BU of 8es6 by Molmil
Crystal structure of an unusual amidase ClbL from colibactin gene cluster
分子名称: Colibactin biosynthesis amidase ClbL
著者Tripathi, P, Bruner, S.D.
登録日2022-10-13
公開日2023-09-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis of the amidase ClbL central to the biosynthesis of the genotoxin colibactin.
Acta Crystallogr D Struct Biol, 79, 2023
7RK0
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BU of 7rk0 by Molmil
Crystal structure of Thermovibrio ammonificans THI4
分子名称: 2-[(E)-[(4R)-5-[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-4-oxidanyl-3-oxidanylidene-pentan-2-ylidene]amino]ethanoic acid, FE (III) ION, Thiamine thiazole synthase
著者Li, Q, Bruner, S.D.
登録日2021-07-21
公開日2021-09-01
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Structure and function of aerotolerant, multiple-turnover THI4 thiazole synthases.
Biochem.J., 478, 2021
8UO7
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BU of 8uo7 by Molmil
Bovine trypsin in complex with deacetylated wild type microviridin J
分子名称: CALCIUM ION, Cationic trypsin, Deacetylated wildtype microviridin J, ...
著者Chen, W, Bruner, S.D.
登録日2023-10-19
公開日2024-02-14
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Alternative Linkage Chemistries in the Chemoenzymatic Synthesis of Microviridin-Based Cyclic Peptides.
Org.Lett., 26, 2024
8UTL
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BU of 8utl by Molmil
Bovine trypsin in complex with Thr3Dap mutated microviridin J
分子名称: CALCIUM ION, Cationic trypsin, GLYCEROL, ...
著者Chen, W, Bruner, S.D.
登録日2023-10-31
公開日2024-02-14
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.56 Å)
主引用文献Alternative Linkage Chemistries in the Chemoenzymatic Synthesis of Microviridin-Based Cyclic Peptides.
Org.Lett., 26, 2024
8TYJ
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BU of 8tyj by Molmil
Crystal structure of SARS-CoV-2 nsp10/nsp16 complex with bound SAH
分子名称: 2'-O-methyltransferase, GLYCEROL, Non-structural protein 10, ...
著者Patel, K.P, Bruner, S.D.
登録日2023-08-25
公開日2024-01-24
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of SARS-CoV-2 nsp10/nsp16 complex with bound SAH
To Be Published
1FN7
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BU of 1fn7 by Molmil
COUPLING OF DAMAGE RECOGNITION AND CATALYSIS BY A HUMAN BASE-EXCISION DNA REPAIR PROTEIN
分子名称: 8-OXOGUANINE DNA GLYCOSYLASE 1, CALCIUM ION, DNA (5'-D(*GP*CP*GP*TP*CP*CP*AP*(3DR)P*GP*TP*CP*TP*AP*CP*C)-3'), ...
著者Norman, D.P.G, Bruner, S.D, Verdine, G.L.
登録日2000-08-21
公開日2001-04-21
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Coupling of substrate recognition and catalysis by a human base-excision DNA repair protein.
J.Am.Chem.Soc., 123, 2001
7MTT
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BU of 7mtt by Molmil
Crystal structure of colibactin self-resistance protein ClbS in complex with two molecules of CHES
分子名称: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Colibactin self-protection protein ClbS
著者Tripathi, P, Bruner, S.D.
登録日2021-05-13
公開日2021-05-26
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural Basis for the Interactions of the Colibactin Resistance Gene Product ClbS with DNA.
Biochemistry, 60, 2021
7MTL
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BU of 7mtl by Molmil
Crystal structure of colibactin self-resistance protein ClbS in complex with a dsDNA
分子名称: Colibactin self-protection protein ClbS, DNA (5'-D(*AP*AP*TP*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*AP*G)-3'), DNA (5'-D(*CP*TP*GP*GP*AP*AP*GP*TP*GP*GP*GP*AP*AP*TP*T)-3')
著者Tripathi, P, Bruner, S.D.
登録日2021-05-13
公開日2021-05-26
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.446 Å)
主引用文献Structural Basis for the Interactions of the Colibactin Resistance Gene Product ClbS with DNA.
Biochemistry, 60, 2021
7T2Z
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BU of 7t2z by Molmil
The structure of Haemophilus influenzae Rd KW20 nitroreductase complexed with 1-methyl-5-nitroimidazole
分子名称: 1,2-ETHANEDIOL, 1-methyl-5-nitro-1H-imidazole, ACETIC ACID, ...
著者Wanniarachchi, T.N, Bruner, S.D.
登録日2021-12-06
公開日2022-02-23
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.2547 Å)
主引用文献Biochemical and structural characterization of Haemophilus influenzae nitroreductase in metabolizing nitroimidazoles.
Rsc Chem Biol, 3, 2022
7T33
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BU of 7t33 by Molmil
The structure of Haemophilus influenzae Rd KW20 nitroreductase complexed with nicotinic acid
分子名称: FLAVIN MONONUCLEOTIDE, NICOTINIC ACID, Putative NAD(P)H nitroreductase, ...
著者Wanniarachchi, T.N, Bruner, S.D.
登録日2021-12-06
公開日2022-02-23
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.301 Å)
主引用文献Biochemical and structural characterization of Haemophilus influenzae nitroreductase in metabolizing nitroimidazoles.
Rsc Chem Biol, 3, 2022
3TEJ
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BU of 3tej by Molmil
Crystal structure of a domain fragment involved in peptide natural product biosynthesis
分子名称: Enterobactin synthase component F
著者Liu, Y, Zheng, T, Bruner, S.D.
登録日2011-08-15
公開日2012-01-18
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis for phosphopantetheinyl carrier domain interactions in the terminal module of nonribosomal peptide synthetases.
Chem.Biol., 18, 2011
1HU0
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BU of 1hu0 by Molmil
CRYSTAL STRUCTURE OF AN HOGG1-DNA BOROHYDRIDE TRAPPED INTERMEDIATE COMPLEX
分子名称: 5'-D(*GP*CP*GP*TP*CP*CP*AP*(PED)P*GP*TP*CP*TP*AP*CP*C)-3', 5'-D(*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3', 8-OXOGUANINE, ...
著者Fromme, J.C, Bruner, S.D, Yang, W, Karplus, M, Verdine, G.L.
登録日2001-01-03
公開日2003-02-25
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Product-Assisted Catalysis in base-excision DNA Repair
Nat.Struct.Biol., 10, 2003
1LWW
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BU of 1lww by Molmil
Borohydride-trapped hOgg1 Intermediate Structure Co-Crystallized with 8-bromoguanine
分子名称: 5'-D(*GP*CP*GP*TP*CP*CP*AP*(PED)P*GP*TP*CP*TP*AP*CP*C)-3', 5'-D(*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3', 8-BROMOGUANINE, ...
著者Fromme, J.C, Bruner, S.D, Yang, W, Karplus, M, Verdine, G.L.
登録日2002-06-03
公開日2003-02-25
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Product-Assisted Catalysis in Base Excision DNA Repair
Nat.Struct.Biol., 10, 2003
1LWV
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BU of 1lwv by Molmil
Borohydride-trapped hOgg1 Intermediate Structure Co-Crystallized with 8-aminoguanine
分子名称: 5'-D(*GP*CP*GP*TP*CP*CP*AP*(PED)P*GP*TP*CP*TP*AP*CP*C)-3', 5'-D(*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3', 8-AMINOGUANINE, ...
著者Fromme, J.C, Bruner, S.D, Yang, W, Karplus, M, Verdine, G.L.
登録日2002-06-03
公開日2003-02-25
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Product-Assisted Catalysis in Base Excision DNA Repair
Nat.Struct.Biol., 10, 2003
1LWY
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BU of 1lwy by Molmil
hOgg1 Borohydride-Trapped Intermediate without 8-oxoguanine
分子名称: 5'-D(*GP*CP*GP*TP*CP*CP*AP*(PED)P*GP*TP*CP*TP*AP*CP*C)-3', 5'-D(*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3', 8-OXOGUANINE DNA GLYCOSYLASE
著者Fromme, J.C, Bruner, S.D, Yang, W, Karplus, M, Verdine, G.L.
登録日2002-06-03
公開日2003-02-25
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Product-Assisted Catalysis in Base Excision DNA Repair
Nat.Struct.Biol., 10, 2003
5KAH
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BU of 5kah by Molmil
Crystal structure of a dioxygenase in the Crotonase superfamily in P21, V425T mutant
分子名称: (3,5-dihydroxyphenyl)acetyl-CoA 1,2-dioxygenase, [(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-4-HYDROXY-3-(PHOSPHONOOXY)TETRAHYDROFURAN-2-YL]METHYL (3R)-4-({3-[(2-{[(3,5-DIHYDROXYPHENYL)ACETYL]AMINO}ETHYL)AMINO]-3-OXOPROPYL}AMINO)-3-HYDROXY-2,2-DIMETHYL-4-OXOBUTYL DIHYDROGEN DIPHOSPHATE
著者Li, K, Fielding, E.N, Condurso, H.L, Bruner, S.D.
登録日2016-06-01
公開日2017-06-21
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.779 Å)
主引用文献Probing the structural basis of oxygen binding in a cofactor-independent dioxygenase.
Acta Crystallogr D Struct Biol, 73, 2017
5K3J
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Crystals structure of Acyl-CoA oxidase-2 in Caenorhabditis elegans bound with FAD, ascaroside-CoA, and ATP
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Acyl-coenzyme A oxidase, FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Zhang, X, Li, K, Jones, R.A, Bruner, S.D, Butcher, R.A.
登録日2016-05-19
公開日2016-08-24
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.68 Å)
主引用文献Structural characterization of acyl-CoA oxidases reveals a direct link between pheromone biosynthesis and metabolic state in Caenorhabditis elegans.
Proc.Natl.Acad.Sci.USA, 113, 2016
5KAG
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Crystal structure of a dioxygenase in the Crotonase superfamily in P21
分子名称: (3,5-dihydroxyphenyl)acetyl-CoA 1,2-dioxygenase, OXYGEN MOLECULE, [(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-4-HYDROXY-3-(PHOSPHONOOXY)TETRAHYDROFURAN-2-YL]METHYL (3R)-4-({3-[(2-{[(3,5-DIHYDROXYPHENYL)ACETYL]AMINO}ETHYL)AMINO]-3-OXOPROPYL}AMINO)-3-HYDROXY-2,2-DIMETHYL-4-OXOBUTYL DIHYDROGEN DIPHOSPHATE
著者Li, K, Fielding, E.N, Condurso, H.L, Bruner, S.D.
登録日2016-06-01
公開日2017-06-21
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.456 Å)
主引用文献Probing the structural basis of oxygen binding in a cofactor-independent dioxygenase.
Acta Crystallogr D Struct Biol, 73, 2017

 

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