7T2Z

The structure of Haemophilus influenzae Rd KW20 nitroreductase complexed with 1-methyl-5-nitroimidazole

Summary for 7T2Z

• Entry DOI: 10.2210/pdb7t2z/pdb
• Descriptor: Putative NAD(P)H nitroreductase, 1,2-ETHANEDIOL, FLAVIN MONONUCLEOTIDE, ... (6 entities in total)
• Functional Keywords: nitroreductase, haemophilus influenzae, 1-methyl-5-nitroimidazole, oxidoreductase
• Biological source: Haemophilus influenzae Rd KW20
• Total number of polymer chains: 2
• Total formula weight: 54719.06

Authors

Wanniarachchi, T.N.,Bruner, S.D. (deposition date: 2021-12-06, release date: 2022-02-23, Last modification date: 2023-10-18)

• Primary citation: Liu, D.,Wanniarachchi, T.N.,Jiang, G.,Seabra, G.,Cao, S.,Bruner, S.D.,Ding, Y.; Biochemical and structural characterization of Haemophilus influenzae nitroreductase in metabolizing nitroimidazoles.; Rsc Chem Biol, 3:436-446, 2022; PubMed: 35441146; DOI: 10.1039/d1cb00238d

Experimental method

X-RAY DIFFRACTION (2.2547 Å)