6E8O

Crystal structure of aryl acid adenylating enzyme FscC from Fuscachelin NRPS in complex with AMP

Summary for 6E8O

Entry DOI	10.2210/pdb6e8o/pdb
Descriptor	2,3-dihydroxybenzoate-AMP ligase, ADENOSINE MONOPHOSPHATE, SULFATE ION, ... (5 entities in total)
Functional Keywords	siderophore biosynthesis, nrps, adenylation domain, thiolation state, ligase
Biological source	Thermobifida fusca
Total number of polymer chains	2
Total formula weight	120375.42
Authors	Bruner, S.D.,Zagulyaeva, A.A. (deposition date: 2018-07-30, release date: 2019-08-21, Last modification date: 2023-10-11)
Primary citation	Bruner, S.D.,Zagulyaeva, A.A. Implication of MbtH-like proteins in crystallization of the independent NRPS A domains. Crystal structure of FscC: supporting rationale for revised mechanism of freestanding aryl acid adenylating enzymes To Be Published,
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation