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7RK0

Crystal structure of Thermovibrio ammonificans THI4

Summary for 7RK0
Entry DOI10.2210/pdb7rk0/pdb
DescriptorThiamine thiazole synthase, FE (III) ION, 2-[(E)-[(4R)-5-[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-4-oxidanyl-3-oxidanylidene-pentan-2-ylidene]amino]ethanoic acid, ... (4 entities in total)
Functional Keywordssuicide enzyme, thiamin, thiazole, biosynthetic protein
Biological sourceThermovibrio ammonificans
Total number of polymer chains4
Total formula weight117681.08
Authors
Li, Q.,Bruner, S.D. (deposition date: 2021-07-21, release date: 2021-09-01, Last modification date: 2023-10-18)
Primary citationJoshi, J.,Li, Q.,Garcia-Garcia, J.D.,Leong, B.J.,Hu, Y.,Bruner, S.D.,Hanson, A.D.
Structure and function of aerotolerant, multiple-turnover THI4 thiazole synthases.
Biochem.J., 478:3265-3279, 2021
Cited by
PubMed: 34409984
DOI: 10.1042/BCJ20210565
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.28 Å)
Structure validation

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