1JMK

Structural Basis for the Cyclization of the Lipopeptide Antibiotic Surfactin by the Thioesterase Domain SrfTE

Summary for 1JMK

DescriptorSurfactin Synthetase, SULFATE ION (3 entities in total)
Functional Keywordsthioesterase, non-ribosomal peptide synthesis, alpha-beta hydrolase, cyclic peptide, hydrolase
Biological sourceBacillus subtilis
Total number of polymer chains2
Total molecular weight51577.74
Authors
Bruner, S.D.,Weber, T.,Kohli, R.M.,Schwarzer, D.,Marahiel, M.A.,Walsh, C.T.,Stubbs, M.T. (deposition date: 2001-07-18, release date: 2002-03-27, Last modification date: 2011-07-13)
Primary citation
Bruner, S.D.,Weber, T.,Kohli, R.M.,Schwarzer, D.,Marahiel, M.A.,Walsh, C.T.,Stubbs, M.T.
Structural basis for the cyclization of the lipopeptide antibiotic surfactin by the thioesterase domain SrfTE.
Structure, 10:301-310, 2002
PubMed: 12005429 (PDB entries with the same primary citation)
DOI: 10.1016/S0969-2126(02)00716-5
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.71 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliers0.31190.2%4.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution