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5MME
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BU of 5mme by Molmil
Crystal structure of CREBBP bromodomain complexd with US46C
分子名称: CREB-binding protein, dimethyl 5-[(5-ethanoyl-2-ethoxy-phenyl)amino]benzene-1,3-dicarboxylate
著者Zhu, J, Caflisch, A.
登録日2016-12-09
公開日2017-12-20
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Binding Motifs in the CBP Bromodomain: An Analysis of 20 Crystal Structures of Complexes with Small Molecules.
ACS Med Chem Lett, 9, 2018
4V84
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BU of 4v84 by Molmil
Crystal structure of a complex containing domain 3 of CrPV IGR IRES RNA bound to the 70S ribosome.
分子名称: 23S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
著者Zhu, J, Korostelev, A, Costantino, D, Noller, H.F, Kieft, J.S.
登録日2010-12-13
公開日2014-07-09
最終更新日2019-07-17
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Crystal structures of complexes containing domains from two viral internal ribosome entry site (IRES) RNAs bound to the 70S ribosome.
Proc.Natl.Acad.Sci.USA, 108, 2011
4V83
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BU of 4v83 by Molmil
Crystal structure of a complex containing domain 3 from the PSIV IGR IRES RNA bound to the 70S ribosome.
分子名称: 23S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
著者Zhu, J, Korostelev, A, Costantino, D, Noller, H.F, Kieft, J.S.
登録日2010-12-13
公開日2014-07-09
最終更新日2014-12-10
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Crystal structures of complexes containing domains from two viral internal ribosome entry site (IRES) RNAs bound to the 70S ribosome.
Proc.Natl.Acad.Sci.USA, 108, 2011
6FQO
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BU of 6fqo by Molmil
Crystal structure of CREBBP bromodomain complexd with DT29
分子名称: 1,2-ETHANEDIOL, CREB-binding protein, ~{N}-[3-(2,5-dimethyl-3-oxidanylidene-1,2-oxazol-4-yl)-5-(5-ethanoyl-2-ethoxy-phenyl)phenyl]furan-2-carboxamide
著者Zhu, J, Caflisch, A.
登録日2018-02-14
公開日2018-08-29
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Binding Motifs in the CBP Bromodomain: An Analysis of 20 Crystal Structures of Complexes with Small Molecules.
ACS Med Chem Lett, 9, 2018
6FQU
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BU of 6fqu by Molmil
Crystal structure of CREBBP bromodomain complexd with DR09
分子名称: 1-[3-[3-[3,3-bis(fluoranyl)piperidin-1-yl]phenyl]-4-ethoxy-phenyl]ethanone, CREB-binding protein
著者Zhu, J, Caflisch, A.
登録日2018-02-14
公開日2018-08-29
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.43 Å)
主引用文献Binding Motifs in the CBP Bromodomain: An Analysis of 20 Crystal Structures of Complexes with Small Molecules.
ACS Med Chem Lett, 9, 2018
6FR0
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BU of 6fr0 by Molmil
Crystal structure of CREBBP bromodomain complexd with PB08
分子名称: CREB-binding protein, ~{N}-[3-(5-ethanoyl-2-ethoxy-phenyl)-5-(2-ethyl-5-methyl-3-oxidanylidene-1,2-oxazol-4-yl)phenyl]furan-2-carboxamide
著者Zhu, J, Caflisch, A.
登録日2018-02-15
公開日2018-08-29
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Binding Motifs in the CBP Bromodomain: An Analysis of 20 Crystal Structures of Complexes with Small Molecules.
ACS Med Chem Lett, 9, 2018
6FRF
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BU of 6frf by Molmil
Crystal structure of CREBBP bromodomain complexd with PA10
分子名称: CREB-binding protein, ~{N}-[3-(3,5-dimethyl-1,2-oxazol-4-yl)-5-(5-ethanoyl-2-ethoxy-phenyl)phenyl]furan-2-carboxamide
著者Zhu, J, Caflisch, A.
登録日2018-02-15
公開日2018-08-29
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Binding Motifs in the CBP Bromodomain: An Analysis of 20 Crystal Structures of Complexes with Small Molecules.
ACS Med Chem Lett, 9, 2018
1ZNN
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BU of 1znn by Molmil
Structure of the synthase subunit of PLP synthase
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, PLP SYNTHASE, SULFATE ION
著者Zhu, J, Burgner, J.W, Harms, E, Belitsky, B.R, Smith, J.L.
登録日2005-05-11
公開日2005-05-24
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献A New Arrangement of (beta/alpha)8 Barrels in the Synthase Subunit of PLP Synthase.
J.Biol.Chem., 280, 2005
4YLM
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BU of 4ylm by Molmil
Structure of PvcB, an Fe, alpha-ketoglutarate dependent oxygenase from an isonitrile synthetic pathway
分子名称: GLYCEROL, Pyoverdine biosynthesis protein PvcB
著者Zhu, J, Lippa, G.M, Gulick, A.M, Tipton, P.A.
登録日2015-03-05
公開日2015-04-29
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Examining Reaction Specificity in PvcB, a Source of Diversity in Isonitrile-Containing Natural Products.
Biochemistry, 54, 2015
3FCU
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BU of 3fcu by Molmil
Structure of headpiece of integrin aIIBb3 in open conformation
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CACODYLATE ION, CALCIUM ION, ...
著者Zhu, J, Luo, B.-H, Xiao, T, Zhang, C, Nishida, N, Springer, T.A.
登録日2008-11-22
公開日2009-01-20
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structure of a complete integrin ectodomain in a physiologic resting state and activation and deactivation by applied forces.
Mol.Cell, 32, 2008
5C89
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BU of 5c89 by Molmil
Crystal structure of the human BRPF1 bromodomain in complex with 917
分子名称: 1-ethyl-8-methoxy-5-methyl[1,2,4]triazolo[4,3-a]quinoline, Peregrin
著者Zhu, J, Wiedmer, L, Caflisch, A.
登録日2015-06-25
公開日2016-07-13
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Crystal structure of the human BRPF1 bromodomain in complex with 917
To Be Published
3FCS
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BU of 3fcs by Molmil
Structure of complete ectodomain of integrin aIIBb3
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Zhu, J, Luo, B.-H, Xiao, T, Zhang, C, Nishida, N, Springer, T.A.
登録日2008-11-22
公開日2009-01-20
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Structure of a complete integrin ectodomain in a physiologic resting state and activation and deactivation by applied forces.
Mol.Cell, 32, 2008
6FQT
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BU of 6fqt by Molmil
Crystal structure of CREBBP bromodomain complexd with DR46
分子名称: CREB-binding protein, ~{N}-[3-(5-ethanoyl-2-ethoxy-phenyl)-5-(1-methylpyrazol-3-yl)phenyl]furan-2-carboxamide
著者Zhu, J, Caflisch, A.
登録日2018-02-14
公開日2019-03-13
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of CREBBP bromodomain complexd with DR46
To Be Published
5MPK
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BU of 5mpk by Molmil
Crystal structure of CREBBP bromodomain complexed with DK19
分子名称: CREB-binding protein, ~{N}-(5-ethanoyl-2-ethoxy-phenyl)-3-(2~{H}-1,2,3,4-tetrazol-5-yl)-5-(1,3-thiazol-4-yl)benzamide
著者Zhu, J, Caflisch, A.
登録日2016-12-16
公開日2018-01-17
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Binding Motifs in the CBP Bromodomain: An Analysis of 20 Crystal Structures of Complexes with Small Molecules.
ACS Med Chem Lett, 9, 2018
5MMG
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BU of 5mmg by Molmil
Crystal structure of CREBBP bromodomain complexed with UT07C
分子名称: 1-[4-ethoxy-3-[(1-methylsulfonylindol-6-yl)amino]phenyl]ethanone, CREB-binding protein
著者Zhu, J, Caflisch, A.
登録日2016-12-09
公開日2017-12-20
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.23 Å)
主引用文献Binding Motifs in the CBP Bromodomain: An Analysis of 20 Crystal Structures of Complexes with Small Molecules.
ACS Med Chem Lett, 9, 2018
5MPN
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BU of 5mpn by Molmil
Crystal structure of CREBBP bromodomain complexed with FA26
分子名称: 1,2-ETHANEDIOL, 1-[4-ethoxy-3-[3-(2~{H}-1,2,3,4-tetrazol-5-yl)phenyl]phenyl]ethanone, CREB-binding protein
著者Zhu, J, Caflisch, A.
登録日2016-12-16
公開日2018-01-17
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.23 Å)
主引用文献Binding Motifs in the CBP Bromodomain: An Analysis of 20 Crystal Structures of Complexes with Small Molecules.
ACS Med Chem Lett, 9, 2018
5OWK
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BU of 5owk by Molmil
Crystal structure of CREBBP bromodomain complexed with DSPB2A002
分子名称: CREB-binding protein, ethyl 4-chloranyl-1-methyl-6-oxidanylidene-pyridine-3-carboxylate
著者Zhu, J, Spiliotopoulos, D, Caflisch, A.
登録日2017-09-01
公開日2018-08-29
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Binding Motifs in the CBP Bromodomain: An Analysis of 20 Crystal Structures of Complexes with Small Molecules.
ACS Med Chem Lett, 9, 2018
7RK6
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BU of 7rk6 by Molmil
Aplysia Slo1 with Barium
分子名称: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, BARIUM ION, BK channel, ...
著者Zhu, J, Srivastava, S, Cachau, R, Holmgren, M.
登録日2021-07-22
公開日2022-06-22
最終更新日2023-04-05
実験手法ELECTRON MICROSCOPY (2.91 Å)
主引用文献CryoEM structure of Aplysia Slo1 with 0 mM Ba2+ at 2.91 A
To Be Published
7RJT
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BU of 7rjt by Molmil
Aplysia Slo1 with Barium
分子名称: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, BARIUM ION, BK channel, ...
著者Zhu, J, Srivastava, S, Cachau, R, Holmgren, M.
登録日2021-07-21
公開日2022-06-22
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (2.93 Å)
主引用文献CryoEM structure of Aplysia Slo1 with 10 mM Ba2+ at 2.93 A
To Be Published
5MWG
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BU of 5mwg by Molmil
Crystal structure of the human BRPF1 bromodomain in complex with BZ091
分子名称: NITRATE ION, Peregrin, ~{N}-[1,4-dimethyl-2,3-bis(oxidanylidene)-7-piperidin-1-yl-quinoxalin-6-yl]-5,6,7,8-tetrahydronaphthalene-2-sulfonamide
著者Zhu, J, Caflisch, A.
登録日2017-01-18
公開日2018-02-14
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structure-based discovery of selective BRPF1 bromodomain inhibitors.
Eur J Med Chem, 155, 2018
5MWH
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BU of 5mwh by Molmil
Crystal structure of the human BRPF1 bromodomain in complex with BZ089
分子名称: NITRATE ION, Peregrin, ~{N}-[1,4-dimethyl-7-morpholin-4-yl-2,3-bis(oxidanylidene)quinoxalin-6-yl]-4-(2-methylpropyl)benzenesulfonamide
著者Zhu, J, Caflisch, A.
登録日2017-01-18
公開日2018-02-14
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structure-based discovery of selective BRPF1 bromodomain inhibitors.
Eur J Med Chem, 155, 2018
5MWZ
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BU of 5mwz by Molmil
Crystal structure of the human BRPF1 bromodomain in complex with BZ073
分子名称: Peregrin, ~{N}-[1,4-diethyl-2,3-bis(oxidanylidene)-7-piperidin-1-yl-quinoxalin-6-yl]-2-(4-methylpiperazin-1-yl)ethanamide
著者Zhu, J, Caflisch, A.
登録日2017-01-20
公開日2018-02-14
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Structure-based discovery of selective BRPF1 bromodomain inhibitors.
Eur J Med Chem, 155, 2018
5O55
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BU of 5o55 by Molmil
Crystal structure of the human BRPF1 bromodomain in complex with BZ047
分子名称: NITRATE ION, Peregrin, ~{N}-[(1~{S})-1-(1,5-dimethylpyrazol-4-yl)ethyl]-1-ethyl-3-methyl-2-oxidanylidene-quinoxaline-6-carboxamide
著者Zhu, J, Caflisch, A.
登録日2017-05-31
公開日2018-06-13
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Structure-based discovery of selective BRPF1 bromodomain inhibitors.
Eur J Med Chem, 155, 2018
5O5A
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BU of 5o5a by Molmil
Crystal structure of the human BRPF1 bromodomain in complex with BZ032
分子名称: 1-ethyl-~{N}-methyl-2,3-bis(oxidanylidene)-~{N}-[(1-phenylpyrazol-4-yl)methyl]-4~{H}-quinoxaline-6-carboxamide, NITRATE ION, Peregrin
著者Zhu, J, Caflisch, A.
登録日2017-06-01
公開日2018-06-13
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structure-based discovery of selective BRPF1 bromodomain inhibitors.
Eur J Med Chem, 155, 2018
5O97
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Crystal structure of human BRD4(1) bromodomain in complex with JRMBR4106
分子名称: (5~{Z})-4-azanyl-5-[(3-methoxy-4-oxidanyl-phenyl)methylidene]-1,3-thiazol-2-one, 1,2-ETHANEDIOL, Bromodomain-containing protein 4
著者Zhu, J, Marchand, J.R, Caflisch, A.
登録日2017-06-15
公開日2018-06-27
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Crystal structure of human BRD4(1) bromodomain in complex with JRMBR4106
To Be Published

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