6UYD
| Structure of Hepatitis C Virus Envelope Glycoprotein E2mc3-v1 redesigned core from genotype 1a bound to broadly neutralizing antibody AR3C | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein E2, ... | Authors: | Tzarum, N, Wilson, I.A, Zhu, J. | Deposit date: | 2019-11-13 | Release date: | 2020-04-22 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.897 Å) | Cite: | Proof of concept for rational design of hepatitis C virus E2 core nanoparticle vaccines. Sci Adv, 6, 2020
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3V4V
| crystal structure of a4b7 headpiece complexed with Fab ACT-1 and RO0505376 | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Yu, Y, Zhu, J, Springer, T.A. | Deposit date: | 2011-12-15 | Release date: | 2012-01-11 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structural specializations of a4b7, an Integrin that Mediates Rolling Adhesion J.Cell Biol., 196, 2012
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3V4P
| crystal structure of a4b7 headpiece complexed with Fab ACT-1 | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Yu, Y, Zhu, J, Springer, T.A. | Deposit date: | 2011-12-15 | Release date: | 2012-01-11 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.15 Å) | Cite: | Structural specializations of a4b7, an Integrin that Mediates Rolling Adhesion J.Cell Biol., 196, 2012
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6UYM
| Structure of Hepatitis C Virus Envelope Glycoprotein E2mc3-v6 redesigned core from genotype 1a bound to broadly neutralizing antibody AR3C | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein E2, ... | Authors: | Tzarum, N, Wilson, I.A, Zhu, J. | Deposit date: | 2019-11-13 | Release date: | 2020-04-22 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.848 Å) | Cite: | Proof of concept for rational design of hepatitis C virus E2 core nanoparticle vaccines. Sci Adv, 6, 2020
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6UYF
| Structure of Hepatitis C Virus Envelope Glycoprotein E2mc3-v1 redesigned core from genotype 6a bound to broadly neutralizing antibody AR3B | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein E2, ... | Authors: | Tzarum, N, Wilson, I.A, Zhu, J. | Deposit date: | 2019-11-13 | Release date: | 2020-04-22 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.06 Å) | Cite: | Proof of concept for rational design of hepatitis C virus E2 core nanoparticle vaccines. Sci Adv, 6, 2020
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6UYG
| Structure of Hepatitis C Virus Envelope Glycoprotein E2c3 core from genotype 6a bound to broadly neutralizing antibody AR3A and non neutralizing antibody E1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein E2, ... | Authors: | Tzarum, N, Wilson, I.A, Zhu, J. | Deposit date: | 2019-11-13 | Release date: | 2020-04-22 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.375 Å) | Cite: | Proof of concept for rational design of hepatitis C virus E2 core nanoparticle vaccines. Sci Adv, 6, 2020
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4G1E
| Crystal structure of integrin alpha V beta 3 with coil-coiled tag. | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Dong, X, Mi, L, Zhu, J, Wang, W, Luo, B, Springer, T.A. | Deposit date: | 2012-07-10 | Release date: | 2012-12-12 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | AlphaV Beta3 Integrin Crystal Structures and their Functional Implications Biochemistry, 51, 2012
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4G1M
| Re-refinement of alpha V beta 3 structure | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Springer, T.A, Mi, L, Zhu, J. | Deposit date: | 2012-07-10 | Release date: | 2012-12-12 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Alpha V Beta 3 Integrin Crystal Structures and their Functional Implications Biochemistry, 51, 2012
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4HBQ
| Crystal structure of a loop deleted mutant of Human MAdCAM-1 D1D2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Mucosal addressin cell adhesion molecule 1, ... | Authors: | Springer, T, Yu, Y, Zhu, J. | Deposit date: | 2012-09-28 | Release date: | 2013-01-23 | Last modified: | 2021-05-26 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | A Different Fold with an Integrin-Binding Loop Specialized for Flexibility in Mucosal Addressin Cell Adhesion Molecule-1 TO BE PUBLISHED
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4HD9
| Crystal structure of native human MAdCAM-1 D1D2 domain | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Mucosal addressin cell adhesion molecule 1 | Authors: | Springer, T, Yu, Y, Zhu, J. | Deposit date: | 2012-10-02 | Release date: | 2013-01-23 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | A Different Fold with an Integrin-Binding Loop Specialized for Flexibility in Mucosal Addressin Cell Adhesion Molecule-1 TO BE PUBLISHED
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4NLH
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4JHR
| An auto-inhibited conformation of LGN reveals a distinct interaction mode between GoLoco motifs and TPR motifs | Descriptor: | G-protein-signaling modulator 2 | Authors: | Pan, Z, Zhu, J, Shang, Y, Wei, Z, Jia, M, Xia, C, Wen, W, Wang, W, Zhang, M. | Deposit date: | 2013-03-05 | Release date: | 2013-06-05 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | An autoinhibited conformation of LGN reveals a distinct interaction mode between GoLoco motifs and TPR motifs Structure, 21, 2013
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4HC1
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4HCR
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2VDP
| Integrin AlphaIIbBeta3 Headpiece Bound to Fibrinogen Gamma chain peptide,LGGAKQAGDV | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, FIBRINOGEN, ... | Authors: | Springer, T.A, Zhu, J, Xiao, T. | Deposit date: | 2007-10-10 | Release date: | 2008-09-02 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural Basis for Distinctive Recognition of Fibrinogen Gammac Peptide by the Platelet Integrin Alphaiibbeta3. J.Cell Biol., 182, 2008
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2VDK
| Re-refinement of Integrin AlphaIIbBeta3 Headpiece | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CACODYLATE ION, CALCIUM ION, ... | Authors: | Springer, T.A, Zhu, J, Xiao, T. | Deposit date: | 2007-10-10 | Release date: | 2008-09-02 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural Basis for Distinctive Recognition of Fibrinogen Gammac Peptide by the Platelet Integrin Alphaiibbeta3. J.Cell Biol., 182, 2008
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2VDO
| Integrin AlphaIIbBeta3 Headpiece Bound to Fibrinogen Gamma chain peptide, HHLGGAKQAGDV | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, FIBRINOGEN, ... | Authors: | Springer, T.A, Zhu, J, Xiao, T. | Deposit date: | 2007-10-10 | Release date: | 2008-09-02 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.51 Å) | Cite: | Structural Basis for Distinctive Recognition of Fibrinogen Gammac Peptide by the Platelet Integrin Alphaiibbeta3. J.Cell Biol., 182, 2008
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2VDN
| Re-refinement of Integrin AlphaIIbBeta3 Headpiece Bound to Antagonist Eptifibatide | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, EPTIFIBATIDE, ... | Authors: | Springer, T.A, Zhu, J, Xiao, T. | Deposit date: | 2007-10-10 | Release date: | 2008-09-02 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural Basis for Distinctive Recognition of Fibrinogen Gammac Peptide by the Platelet Integrin Alphaiibbeta3. J.Cell Biol., 182, 2008
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2VDL
| Re-refinement of Integrin AlphaIIbBeta3 Headpiece | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CACODYLATE ION, CALCIUM ION, ... | Authors: | Springer, T.A, Zhu, J, Xiao, T. | Deposit date: | 2007-10-10 | Release date: | 2008-09-02 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Structural Basis for Distinctive Recognition of Fibrinogen Gammac Peptide by the Platelet Integrin Alphaiibbeta3. J.Cell Biol., 182, 2008
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2VDM
| Re-refinement of Integrin AlphaIIbBeta3 Headpiece Bound to Antagonist Tirofiban | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GLYCEROL, ... | Authors: | Springer, T.A, Zhu, J, Xiao, T. | Deposit date: | 2007-10-10 | Release date: | 2008-09-02 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural Basis for Distinctive Recognition of Fibrinogen Gammac Peptide by the Platelet Integrin Alphaiibbeta3. J.Cell Biol., 182, 2008
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2VDR
| Integrin AlphaIIbBeta3 Headpiece Bound to a chimeric Fibrinogen Gamma chain peptide, LGGAKQRGDV | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, FIBRINOGEN, ... | Authors: | Springer, T.A, Zhu, J, Xiao, T. | Deposit date: | 2007-10-10 | Release date: | 2008-09-02 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural Basis for Distinctive Recognition of Fibrinogen Gammac Peptide by the Platelet Integrin Alphaiibbeta3. J.Cell Biol., 182, 2008
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2VC2
| Re-refinement of Integrin AlphaIIbBeta3 Headpiece Bound to Antagonist L-739758 | Descriptor: | 2-(S)-[N-(3-PYRIDYLSULFONYL)AMINO]-3-[[2-CARBONYL-5-[2-(PIPERIDIN-4-YL)ETHYL]-THIENO[2,3-B]THIOPHENEYL]AMINO]-PROPIONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Springer, T.A, Zhu, J, Xiao, T. | Deposit date: | 2007-09-18 | Release date: | 2008-09-02 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structural Basis for Distinctive Recognition of Fibrinogen Gammac Peptide by the Platelet Integrin Alphaiibbeta3. J.Cell Biol., 182, 2008
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2VDQ
| Integrin AlphaIIbBeta3 Headpiece Bound to a Chimeric Fibrinogen Gamma chain peptide, HHLGGAKQRGDV | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, FIBRINOGEN, ... | Authors: | Springer, T.A, Zhu, J, Xiao, T. | Deposit date: | 2007-10-10 | Release date: | 2008-09-02 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.59 Å) | Cite: | Structural Basis for Distinctive Recognition of Fibrinogen Gammac Peptide by the Platelet Integrin Alphaiibbeta3. J.Cell Biol., 182, 2008
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5XZR
| The atomic structure of SHP2 E76A mutant in complex with allosteric inhibitor 9b | Descriptor: | 4-(3-phenylphenyl)-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3-thiazol-2-amine, Tyrosine-protein phosphatase non-receptor type 11 | Authors: | Li, D, Xie, J, Zhu, J, Liu, C. | Deposit date: | 2017-07-13 | Release date: | 2017-12-13 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Allosteric Inhibitors of SHP2 with Therapeutic Potential for Cancer Treatment. J. Med. Chem., 60, 2017
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7CFU
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