4JHR

An auto-inhibited conformation of LGN reveals a distinct interaction mode between GoLoco motifs and TPR motifs

Summary for 4JHR

DescriptorG-protein-signaling modulator 2 (1 entity in total)
Functional Keywordstpr motifs, goloco tandem motifs, asymmetric cell division, lgn, goloco, signaling protein
Biological sourceMus musculus (mouse)
Cellular locationCytoplasm  Q8VDU0
Total number of polymer chains2
Total molecular weight73758.41
Authors
Pan, Z.,Zhu, J.,Shang, Y.,Wei, Z.,Jia, M.,Xia, C.,Wen, W.,Wang, W.,Zhang, M. (deposition date: 2013-03-05, release date: 2013-06-05, Last modification date: 2017-08-02)
Primary citation
Pan, Z.,Zhu, J.,Shang, Y.,Wei, Z.,Jia, M.,Xia, C.,Wen, W.,Wang, W.,Zhang, M.
An autoinhibited conformation of LGN reveals a distinct interaction mode between GoLoco motifs and TPR motifs
Structure, 21:1007-1017, 2013
PubMed: 23665171 (PDB entries with the same primary citation)
DOI: 10.1016/j.str.2013.04.005
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.8 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.32990.2%9.5%1.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution