4JHR

An auto-inhibited conformation of LGN reveals a distinct interaction mode between GoLoco motifs and TPR motifs

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	G-protein-signaling modulator 2	polymer	333	36879.2	2	UniProt (Q8VDU0) Pfam (PF13424) Pfam (PF13176) Pfam (PF13181) Pfam (PF02188)	Mus musculus (mouse)	Pins homolog

Sequence modifications

A, B: 89 - 350 (UniProt: Q8VDU0)

PDB	External Database	Details
Gly 85	-	expression tag
Pro 86	-	expression tag
Gly 87	-	expression tag
Ser 88	-	expression tag

A, B: 586 - 644 (UniProt: Q8VDU0)

PDB	External Database	Details
Leu 351	-	expression tag
Glu 352	-	expression tag
Val 353	-	expression tag
Leu 354	-	expression tag
Phe 355	-	expression tag
Gln 356	-	expression tag
Gly 357	-	expression tag
Pro 358	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	73758.4
All*	Total formula weight	73758.4

*Water molecules are not included.