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5B4J
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BU of 5b4j by Molmil
Crystal structure of I86D mutant of phycocyanobilin:ferredoxin oxidoreductase in complex with biliverdin (data 3)
Descriptor: BILIVERDINE IX ALPHA, Phycocyanobilin:ferredoxin oxidoreductase
Authors:Hagiwara, Y, Wada, K, Irikawa, T, Unno, M, Fukuyama, K, Sugishima, M.
Deposit date:2016-04-04
Release date:2017-03-15
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.05 Å)
Cite:Atomic-resolution structure of the phycocyanobilin:ferredoxin oxidoreductase I86D mutant in complex with fully protonated biliverdin
FEBS Lett., 590, 2016
7V4N
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BU of 7v4n by Molmil
Unique non-heme hydroxylase in biosynthesis of nucleoside antibiotic pathway uncover mechanism of reaction
Descriptor: Beta-hydroxylase, FE (III) ION
Authors:Li, T.L, Saeid, M.Z.
Deposit date:2021-08-13
Release date:2022-02-23
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:beta-Hydroxylation of alpha-amino-beta-hydroxylbutanoyl-glycyluridine catalyzed by a nonheme hydroxylase ensures the maturation of caprazamycin
Commun Chem, 5, 2022
7V4O
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BU of 7v4o by Molmil
Unique non-heme hydroxylase in biosynthesis of nucleoside antibiotic pathway uncover mechanism of reaction
Descriptor: 3,6,9,12,15-PENTAOXAHEPTADECANE, Beta-hydroxylase
Authors:Li, T.L, Saeid, M.Z.
Deposit date:2021-08-13
Release date:2022-02-23
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:beta-Hydroxylation of alpha-amino-beta-hydroxylbutanoyl-glycyluridine catalyzed by a nonheme hydroxylase ensures the maturation of caprazamycin
Commun Chem, 5, 2022
7V4M
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BU of 7v4m by Molmil
Unique non-heme hydroxylase in biosynthesis of nucleoside antibiotic pathway uncover mechanism of reaction
Descriptor: 2-OXOGLUTARIC ACID, Beta-hydroxylase, FE (III) ION, ...
Authors:Li, T.L, Saeid, M.Z.
Deposit date:2021-08-13
Release date:2022-02-23
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:beta-Hydroxylation of alpha-amino-beta-hydroxylbutanoyl-glycyluridine catalyzed by a nonheme hydroxylase ensures the maturation of caprazamycin
Commun Chem, 5, 2022
7V4F
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BU of 7v4f by Molmil
Unique non-heme hydroxylase in biosynthesis of nucleoside antibiotic pathway uncover mechanism of reaction
Descriptor: (2S,3S)-2-azanyl-4-(2-hydroxy-2-oxoethylamino)-3-oxidanyl-butanoic acid, Beta-hydroxylase, CARBON DIOXIDE, ...
Authors:Li, T.L, Saeid, M.Z.
Deposit date:2021-08-13
Release date:2022-02-23
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:beta-Hydroxylation of alpha-amino-beta-hydroxylbutanoyl-glycyluridine catalyzed by a nonheme hydroxylase ensures the maturation of caprazamycin
Commun Chem, 5, 2022
7V4P
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BU of 7v4p by Molmil
Unique non-heme hydroxylase in biosynthesis of nucleoside antibiotic pathway uncover mechanism of reaction
Descriptor: Beta-hydroxylase, FE (III) ION
Authors:Li, T.L, Saeid, M.Z.
Deposit date:2021-08-13
Release date:2022-02-23
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:beta-Hydroxylation of alpha-amino-beta-hydroxylbutanoyl-glycyluridine catalyzed by a nonheme hydroxylase ensures the maturation of caprazamycin
Commun Chem, 5, 2022
2K86
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BU of 2k86 by Molmil
Solution Structure of FOXO3a Forkhead domain
Descriptor: Forkhead box protein O3
Authors:Wang, F, Marshall, C.B, Li, G, Plevin, M.J, Ikura, M.
Deposit date:2008-09-02
Release date:2008-10-14
Last modified:2020-02-19
Method:SOLUTION NMR
Cite:Biochemical and structural characterization of an intramolecular interaction in FOXO3a and its binding with p53.
J.Mol.Biol., 384, 2008
1BMD
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BU of 1bmd by Molmil
DETERMINANTS OF PROTEIN THERMOSTABILITY OBSERVED IN THE 1.9 ANGSTROMS CRYSTAL STRUCTURE OF MALATE DEHYDROGENASE FROM THE THERMOPHILIC BACTERIUM THERMUS FLAVUS
Descriptor: MALATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Kelly, C.A, Birktoft, J.J.
Deposit date:1992-11-10
Release date:1994-07-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Determinants of protein thermostability observed in the 1.9-A crystal structure of malate dehydrogenase from the thermophilic bacterium Thermus flavus.
Biochemistry, 32, 1993
3UMV
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BU of 3umv by Molmil
Eukaryotic Class II CPD photolyase structure reveals a basis for improved UV-tolerance in plants
Descriptor: 1,2-ETHANEDIOL, Deoxyribodipyrimidine photo-lyase, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Arvai, A.S, Hitomi, K, Getzoff, E.D, Tainer, J.A.
Deposit date:2011-11-14
Release date:2011-12-21
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.705 Å)
Cite:Eukaryotic Class II Cyclobutane Pyrimidine Dimer Photolyase Structure Reveals Basis for Improved Ultraviolet Tolerance in Plants.
J.Biol.Chem., 287, 2012
5BXT
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BU of 5bxt by Molmil
LNBase in complex with LNB-NHAcAUS
Descriptor: Lacto-N-biosidase, N-{[(1R,2R,3R,7S,7aR)-1,2,7-trihydroxyhexahydro-1H-pyrrolizin-3-yl]methyl}acetamide, SULFATE ION, ...
Authors:Ito, T, Arakawa, T, Fushinobu, S.
Deposit date:2015-06-09
Release date:2015-09-09
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Gaining insight into the catalysis by GH20 lacto-N-biosidase using small molecule inhibitors and structural analysis
Chem.Commun.(Camb.), 51, 2015
5BXP
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BU of 5bxp by Molmil
LNBase in complex with LNB-LOGNAc
Descriptor: Lacto-N-biosidase, SULFATE ION, beta-D-galactopyranose-(1-3)-N-acetylglucosaminono-1,5-lactone (Z)-oxime
Authors:Ito, T, Arakawa, T, Fushinobu, S.
Deposit date:2015-06-09
Release date:2015-09-09
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Gaining insight into the catalysis by GH20 lacto-N-biosidase using small molecule inhibitors and structural analysis
Chem.Commun.(Camb.), 51, 2015
5BXS
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BU of 5bxs by Molmil
LNBase in complex with LNB-NHAcCAS
Descriptor: 6-ACETAMIDO-6-DEOXY-CASTANOSPERMINE, Lacto-N-biosidase, SULFATE ION, ...
Authors:Ito, T, Arakawa, T, Fushinobu, S.
Deposit date:2015-06-09
Release date:2015-09-09
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Gaining insight into the catalysis by GH20 lacto-N-biosidase using small molecule inhibitors and structural analysis
Chem.Commun.(Camb.), 51, 2015
5BXR
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BU of 5bxr by Molmil
LNBase in complex with LNB-NHAcDNJ
Descriptor: 2-ACETAMIDO-1,2-DIDEOXYNOJIRMYCIN, Lacto-N-biosidase, SULFATE ION, ...
Authors:Ito, T, Arakawa, T, Fushinobu, S.
Deposit date:2015-06-09
Release date:2015-09-09
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Gaining insight into the catalysis by GH20 lacto-N-biosidase using small molecule inhibitors and structural analysis
Chem.Commun.(Camb.), 51, 2015
7CD0
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BU of 7cd0 by Molmil
Crystal structure of the 2-iodoporphobilinogen-bound ES2 intermediate form of human hydroxymethylbilane synthase
Descriptor: 3-[4-(2-hydroxy-2-oxoethyl)-5-[[4-(2-hydroxy-2-oxoethyl)-5-[[4-(2-hydroxy-2-oxoethyl)-5-[[4-(2-hydroxy-2-oxoethyl)-3-(3-hydroxy-3-oxopropyl)-5-methyl-1~{H}-pyrrol-2-yl]methyl]-3-(3-hydroxy-3-oxopropyl)-1~{H}-pyrrol-2-yl]methyl]-3-(3-hydroxy-3-oxopropyl)-1~{H}-pyrrol-2-yl]methyl]-1~{H}-pyrrol-3-yl]propanoic acid, 3-[5-(aminomethyl)-4-(carboxymethyl)-2-iodo-1H-pyrrol-3-yl]propanoic acid, Porphobilinogen deaminase
Authors:Sato, H, Sugishima, M, Wada, K, Hirabayashi, K, Tsukaguchi, M.
Deposit date:2020-06-18
Release date:2021-03-17
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Crystal structures of hydroxymethylbilane synthase complexed with a substrate analog: a single substrate-binding site for four consecutive condensation steps.
Biochem.J., 478, 2021
7CCZ
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BU of 7ccz by Molmil
Crystal structure of the ES2 intermediate form of human hydroxymethylbilane synthase
Descriptor: 3-[4-(2-hydroxy-2-oxoethyl)-5-[[4-(2-hydroxy-2-oxoethyl)-5-[[4-(2-hydroxy-2-oxoethyl)-5-[[4-(2-hydroxy-2-oxoethyl)-3-(3-hydroxy-3-oxopropyl)-5-methyl-1~{H}-pyrrol-2-yl]methyl]-3-(3-hydroxy-3-oxopropyl)-1~{H}-pyrrol-2-yl]methyl]-3-(3-hydroxy-3-oxopropyl)-1~{H}-pyrrol-2-yl]methyl]-1~{H}-pyrrol-3-yl]propanoic acid, Porphobilinogen deaminase
Authors:Sato, H, Sugishima, M, Wada, K, Hirabayashi, K, Tsukaguchi, M.
Deposit date:2020-06-18
Release date:2021-03-17
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Crystal structures of hydroxymethylbilane synthase complexed with a substrate analog: a single substrate-binding site for four consecutive condensation steps.
Biochem.J., 478, 2021
7CCX
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BU of 7ccx by Molmil
Crystal structure of the holo form of human hydroxymethylbilane synthase
Descriptor: 3-[5-{[3-(2-carboxyethyl)-4-(carboxymethyl)-5-methyl-1H-pyrrol-2-yl]methyl}-4-(carboxymethyl)-1H-pyrrol-3-yl]propanoic acid, Porphobilinogen deaminase
Authors:Sato, H, Sugishima, M, Wada, K, Hirabayashi, K, Tsukaguchi, M.
Deposit date:2020-06-18
Release date:2021-03-17
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Crystal structures of hydroxymethylbilane synthase complexed with a substrate analog: a single substrate-binding site for four consecutive condensation steps.
Biochem.J., 478, 2021
7CCY
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BU of 7ccy by Molmil
Crystal structure of the 2-iodoporphobilinogen-bound holo form of human hydroxymethylbilane synthase
Descriptor: 3-[5-(aminomethyl)-4-(carboxymethyl)-2-iodo-1H-pyrrol-3-yl]propanoic acid, 3-[5-{[3-(2-carboxyethyl)-4-(carboxymethyl)-5-methyl-1H-pyrrol-2-yl]methyl}-4-(carboxymethyl)-1H-pyrrol-3-yl]propanoic acid, Porphobilinogen deaminase
Authors:Sato, H, Sugishima, M, Wada, K, Hirabayashi, K, Tsukaguchi, M.
Deposit date:2020-06-18
Release date:2021-03-17
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structures of hydroxymethylbilane synthase complexed with a substrate analog: a single substrate-binding site for four consecutive condensation steps.
Biochem.J., 478, 2021
2Z8F
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BU of 2z8f by Molmil
The galacto-N-biose-/lacto-N-biose I-binding protein (GL-BP) of the ABC transporter from Bifidobacterium longum in complex with lacto-N-tetraose
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Galacto-N-biose/lacto-N-biose I transporter substrate-binding protein, SODIUM ION, ...
Authors:Suzuki, R, Wada, J, Katayama, T, Fushinobu, S.
Deposit date:2007-09-05
Release date:2008-03-18
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structural and thermodynamic analyses of solute-binding Protein from Bifidobacterium longum specific for core 1 disaccharide and lacto-N-biose I.
J.Biol.Chem., 283, 2008
2Z8D
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BU of 2z8d by Molmil
The galacto-N-biose-/lacto-N-biose I-binding protein (GL-BP) of the ABC transporter from Bifidobacterium longum in complex with lacto-N-biose
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Galacto-N-biose/lacto-N-biose I transporter substrate-binding protein, ZINC ION, ...
Authors:Suzuki, R, Wada, J, Katayama, T, Fushinobu, S.
Deposit date:2007-09-05
Release date:2008-03-18
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural and thermodynamic analyses of solute-binding Protein from Bifidobacterium longum specific for core 1 disaccharide and lacto-N-biose I.
J.Biol.Chem., 283, 2008
2Z8E
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BU of 2z8e by Molmil
The galacto-N-biose-/lacto-N-biose I-binding protein (GL-BP) of the ABC transporter from Bifidobacterium longum in complex with galacto-N-biose
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Galacto-N-biose/lacto-N-biose I transporter substrate-binding protein, ZINC ION, ...
Authors:Suzuki, R, Wada, J, Katayama, T, Fushinobu, S.
Deposit date:2007-09-05
Release date:2008-03-18
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Structural and thermodynamic analyses of solute-binding Protein from Bifidobacterium longum specific for core 1 disaccharide and lacto-N-biose I.
J.Biol.Chem., 283, 2008
8HHQ
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BU of 8hhq by Molmil
Covalent bond formation between cysteine of PPARg-LBD and iodoacetic acid
Descriptor: GLYCOLIC ACID, Peroxisome proliferator-activated receptor gamma
Authors:Kojima, H, Itoh, T.
Deposit date:2022-11-16
Release date:2023-09-20
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Covalent Modifier Discovery Using Hydrogen/Deuterium Exchange-Mass Spectrometry.
J.Med.Chem., 66, 2023
8HHP
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BU of 8hhp by Molmil
Crystal structure of PPARg-LBD complexed with three partial agonists, one nTZDpa and two LT175
Descriptor: (2S)-2-(biphenyl-4-yloxy)-3-phenylpropanoic acid, 5-CHLORO-1-(4-CHLOROBENZYL)-3-(PHENYLTHIO)-1H-INDOLE-2-CARBOXYLIC ACID, Peroxisome proliferator-activated receptor gamma
Authors:Kojima, H, Itoh, T.
Deposit date:2022-11-16
Release date:2023-11-22
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Covalent Modifier Discovery by Hydrogen/Deuterium Exchange Mass Spectrometry (HDX-MS)
To Be Published
2VV3
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BU of 2vv3 by Molmil
hPPARgamma Ligand binding domain in complex with 4-oxoDHA
Descriptor: (6E,10Z,13Z,16Z,19Z)-4-oxodocosa-6,10,13,16,19-pentaenoic acid, PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA
Authors:Itoh, T, Fairall, L, Schwabe, J.W.R.
Deposit date:2008-06-02
Release date:2008-08-19
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structural Basis for the Activation of Ppargamma by Oxidized Fatty Acids.
Nat.Struct.Mol.Biol., 15, 2008
2VSR
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BU of 2vsr by Molmil
hPPARgamma Ligand binding domain in complex with 9-(S)-HODE
Descriptor: (9S,10E,12Z)-9-hydroxyoctadeca-10,12-dienoic acid, PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA
Authors:Itoh, T, Fairall, L, Schwabe, J.W.R.
Deposit date:2008-04-29
Release date:2008-08-19
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural Basis for the Activation of Pparg by Oxidised Fatty Acids
Nat.Struct.Mol.Biol., 15, 2008
2VV0
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BU of 2vv0 by Molmil
hPPARgamma Ligand binding domain in complex with DHA
Descriptor: DOCOSA-4,7,10,13,16,19-HEXAENOIC ACID, PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA
Authors:Itoh, T, Fairall, L, Schwabe, J.W.R.
Deposit date:2008-06-02
Release date:2008-08-19
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structural Basis for the Activation of Pparg by Oxidised Fatty Acids
Nat.Struct.Mol.Biol., 15, 2008

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