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7E8L
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The structure of Spodoptera litura chemosensory protein
分子名称: Putative chemosensory protein CSP8
著者Xie, W, Jia, Q, Zeng, H, Xiao, N, Tang, J, Gao, S, Zhang, J.
登録日2021-03-02
公開日2022-03-02
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The Crystal Structure of the Spodoptera litura Chemosensory Protein CSP8.
Insects, 12, 2021
7EEY
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The structure of the N-terminal doamin of the Schizosaccharomyces pombe Tad2 adenosine deaminase
分子名称: SULFATE ION, tRNA-specific adenosine deaminase subunit tad2
著者Xie, W, Liu, X, Zhou, J.
登録日2021-03-19
公開日2022-03-23
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Functional and structural investigation of N-terminal domain of the SpTad2/3 heterodimeric tRNA deaminase.
Comput Struct Biotechnol J, 19, 2021
7EZG
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The structure of the human METTL6 enzyme in complex with SAH
分子名称: S-ADENOSYL-L-HOMOCYSTEINE, tRNA N(3)-methylcytidine methyltransferase METTL6
著者Xie, W, Chen, R, Zhou, J, Liu, L.
登録日2021-06-01
公開日2022-01-12
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of human METTL6, the m 3 C methyltransferase.
Commun Biol, 4, 2021
4X0R
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Crystal structure of human MxB stalk domain
分子名称: Interferon-induced GTP-binding protein Mx2
著者Yu, X.-F, Xie, W.
登録日2014-11-23
公開日2014-12-10
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.905 Å)
主引用文献Structural insight into the assembly of human anti-HIV dynamin-like protein MxB/Mx2.
Biochem.Biophys.Res.Commun., 456, 2015
6WXY
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crystal structure of cA6-bound Card1
分子名称: Card1, cA6
著者Rostol, J, Xie, W, Patel, D.J, Marraffini, L.
登録日2020-05-12
公開日2020-12-30
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The Card1 nuclease provides defence during type III CRISPR immunity.
Nature, 590, 2021
6WXW
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crystal structure of apo Card1
分子名称: Card1
著者Rostol, J, Xie, W, Patel, D.J, Marraffini, L.
登録日2020-05-12
公開日2020-12-30
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.32 Å)
主引用文献The Card1 nuclease provides defence during type III CRISPR immunity.
Nature, 590, 2021
6WXX
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crystal structure of cA4-activated Card1
分子名称: Card1, MANGANESE (II) ION, cA4
著者Rostol, J, Xie, W, Patel, D.J, Marraffini, L.
登録日2020-05-12
公開日2020-12-30
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The Card1 nuclease provides defence during type III CRISPR immunity.
Nature, 590, 2021
6XL1
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crystal structure of cA4-activated Card1(D294N)
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Card1, MANGANESE (II) ION, ...
著者Rostol, J, Xie, W, Patel, D.J, Marraffini, L.
登録日2020-06-27
公開日2020-12-30
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献The Card1 nuclease provides defence during type III CRISPR immunity.
Nature, 590, 2021
1YN7
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Crystal structure of a mouse MHC class I protein, H2-Db, in complex with a mutated peptide (R7A) of the influenza A acid polymerase
分子名称: 10-mer peptide from RNA-directed RNA polymerase subunit P2, Beta-2-microglobulin, H-2 class I histocompatibility antigen, ...
著者Turner, S.J, Kedzierska, K, Komodromou, H, La Gruta, N.L, Dunstone, M.A, Webb, A.I, Webby, R, Walden, H, Xie, W, McCluskey, J, Purcell, A.W, Rossjohn, J, Doherty, P.C.
登録日2005-01-24
公開日2005-06-28
最終更新日2021-11-10
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Lack of prominent peptide-major histocompatibility complex features limits repertoire diversity in virus-specific CD8+ T cell populations
Nat.Immunol., 6, 2005
1YN6
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Crystal structure of a mouse MHC class I protein, H2-Db, in complex with a peptide from the influenza A acid polymerase
分子名称: 10-mer peptide from RNA-directed RNA polymerase subunit P2, Beta-2-microglobulin, H-2 class I histocompatibility antigen, ...
著者Turner, S.J, Kedzierska, K, Komodromou, H, La Gruta, N.L, Dunstone, M.A, Webb, A.I, Webby, R, Walden, H, Xie, W, McCluskey, J, Purcell, A.W, Rossjohn, J, Doherty, P.C.
登録日2005-01-23
公開日2005-06-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Lack of prominent peptide-major histocompatibility complex features limits repertoire diversity in virus-specific CD8+ T cell populations
Nat.Immunol., 6, 2005
6IPB
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Crystal Structure of the Cofactor-binding Domain of the Human Phase II Drug Metabolism Enzyme UGT2B15
分子名称: GLYCEROL, L(+)-TARTARIC ACID, UDP-glucuronosyltransferase 2B15
著者Zhang, L, Xie, W, Wang, C.
登録日2018-11-02
公開日2020-01-15
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Insight into tartrate inhibition patterns in vitro and in vivo based on cocrystal structure with UDP-glucuronosyltransferase 2B15.
Biochem. Pharmacol., 172, 2019
4KR2
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Glycyl-tRNA synthetase in complex with tRNA-Gly
分子名称: ADENOSINE MONOPHOSPHATE, Gly-tRNA-CCC, Glycine--tRNA ligase
著者Qin, X, Hao, Z, Tian, Q, Zhang, Z, Zhou, C, Xie, W.
登録日2013-05-16
公開日2014-05-21
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.292 Å)
主引用文献Cocrystal Structures of Glycyl-tRNA Synthetase in Complex with tRNA Suggest Multiple Conformational States in Glycylation
J.Biol.Chem., 289, 2014
4KR3
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Glycyl-tRNA synthetase mutant E71G in complex with tRNA-Gly
分子名称: GLYCINE, Gly-tRNA-CCC, Glycine--tRNA ligase, ...
著者Qin, X, Hao, Z, Tian, Q, Zhang, Z, Zhou, C, Xie, W.
登録日2013-05-16
公開日2014-05-21
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (3.235 Å)
主引用文献Cocrystal Structures of Glycyl-tRNA Synthetase in Complex with tRNA Suggest Multiple Conformational States in Glycylation
J.Biol.Chem., 289, 2014
4KQE
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The mutant structure of the human glycyl-tRNA synthetase E71G
分子名称: GLYCEROL, Glycine--tRNA ligase
著者Qin, X, Hao, Z, Tian, Q, Zhang, Z, Zhou, C, Xie, W.
登録日2013-05-15
公開日2014-05-21
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.739 Å)
主引用文献Large Conformational Changes of Insertion 3 in Human Glycyl-tRNA Synthetase (hGlyRS) during Catalysis
J.Biol.Chem., 291, 2016
5GZS
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Structure of VC protein
分子名称: ARGININE, GGDEF family protein
著者Xu, M, Wang, Y.Z, Yang, X.A, Xie, W, Jiang, T.
登録日2016-10-01
公開日2017-08-16
実験手法X-RAY DIFFRACTION (2.601 Å)
主引用文献Structural studies of the periplasmic portion of the diguanylate cyclase CdgH from Vibrio cholerae.
Sci Rep, 7, 2017
5GJB
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Zika virus NS3 helicase in complex with ssRNA
分子名称: NS3 helicase, RNA (5'-R(*AP*GP*AP*UP*CP*AP*A)-3')
著者Tian, H.L, Ji, X.Y, Yang, X.Y, Zhang, Z.X, Lu, Z.K, Yang, K.L, Chen, C, Zhao, Q, Chi, H, Mu, Z.Y, Xie, W, Wang, Z.F, Lou, H.Q, Yang, H.T, Rao, Z.H.
登録日2016-06-28
公開日2016-07-20
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.702 Å)
主引用文献Structural basis of Zika virus helicase in recognizing its substrates
Protein Cell, 7, 2016
5GJC
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Zika virus NS3 helicase in complex with ATP
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, NS3 helicase
著者Tian, H.L, Ji, X.Y, Yang, X.Y, Zhang, Z.X, Lu, Z.K, Yang, K.L, Chen, C, Zhao, Q, Chi, H, Mu, Z.Y, Xie, W, Wang, Z.F, Lou, H.Q, Yang, H.T, Rao, Z.H.
登録日2016-06-28
公開日2016-07-20
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.204 Å)
主引用文献Structural basis of Zika virus helicase in recognizing its substrates
Protein Cell, 7, 2016
5JMT
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Crystal structure of Zika virus NS3 helicase
分子名称: NS3 helicase
著者Tian, H, Ji, X, Yang, X, Xie, W, Yang, K, Chen, C, Wu, C, Chi, H, Mu, Z, Wang, Z, Yang, H.
登録日2016-04-29
公開日2016-05-25
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.796 Å)
主引用文献The crystal structure of Zika virus helicase: basis for antiviral drug design
Protein Cell, 7, 2016
5X8Y
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A Mutation identified in Neonatal Microcephaly Destabilizes Zika Virus NS1 Assembly in vitro
分子名称: ZIKV NS1
著者Wang, D, Chen, C, Liu, S, Zhou, H, Yang, K, Zhao, Q, Ji, X, Chen, C, Xie, W, Wang, Z, Mi, L.Z, Yang, H.
登録日2017-03-03
公開日2017-05-17
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.817 Å)
主引用文献A Mutation Identified in Neonatal Microcephaly Destabilizes Zika Virus NS1 Assembly in Vitro
Sci Rep, 7, 2017
6KEA
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crystal structure of MBP-tagged REV7-IpaB complex
分子名称: Maltose-binding periplasmic protein,LINKER,hREV7,LINKER,Invasin IpaB,hREV3
著者Wang, X, Pernicone, N, Pertz, L, Hua, D.P, Zhang, T.Q, Listovsky, T, Xie, W.
登録日2019-07-04
公開日2019-09-11
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献REV7 has a dynamic adaptor region to accommodate small GTPase RAN/ShigellaIpaB ligands, and its activity is regulated by the RanGTP/GDP switch.
J.Biol.Chem., 294, 2019
6MJW
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human cGAS catalytic domain bound with the inhibitor G150
分子名称: 1-[9-(6-aminopyridin-3-yl)-6,7-dichloro-1,3,4,5-tetrahydro-2H-pyrido[4,3-b]indol-2-yl]-2-hydroxyethan-1-one, Cyclic GMP-AMP synthase, ZINC ION
著者Lama, L, Adura, C, Xie, W, Tomita, D, Kamei, T, Kuryavyi, V, Gogakos, T, Steinberg, J.I, Miller, M, Ramos-Espiritu, L, Asano, Y, Hashizume, S, Aida, J, Imaeda, T, Okamoto, R, Jennings, A.J, Michinom, M, Kuroita, T, Stamford, A, Gao, P, Meinke, P, Glickman, J.F, Patel, D.J, Tuschl, T.
登録日2018-09-23
公開日2019-05-29
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.405 Å)
主引用文献Development of human cGAS-specific small-molecule inhibitors for repression of dsDNA-triggered interferon expression.
Nat Commun, 10, 2019
6MJU
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human cGAS catalytic domain bound with the inhibitor G108
分子名称: 1-[6,7-dichloro-9-(1H-pyrazol-4-yl)-1,3,4,5-tetrahydro-2H-pyrido[4,3-b]indol-2-yl]-2-hydroxyethan-1-one, Cyclic GMP-AMP synthase, ZINC ION
著者Lama, L, Adura, C, Xie, W, Tomita, D, Kamei, T, Kuryavyi, V, Gogakos, T, Steinberg, J.I, Miller, M, Ramos-Espiritu, L, Asano, Y, Hashizume, S, Aida, J, Imaeda, T, Okamoto, R, Jennings, A.J, Michinom, M, Kuroita, T, Stamford, A, Gao, P, Meinke, P, Glickman, J.F, Patel, D.J, Tuschl, T.
登録日2018-09-22
公開日2019-05-29
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Development of human cGAS-specific small-molecule inhibitors for repression of dsDNA-triggered interferon expression.
Nat Commun, 10, 2019
6MJX
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human cGAS catalytic domain bound with cGAMP
分子名称: Cyclic GMP-AMP synthase, ZINC ION, cGAMP
著者Lama, L, Adura, C, Xie, W, Tomita, D, Kamei, T, Kuryavyi, V, Gogakos, T, Steinberg, J.I, Miller, M, Ramos-Espiritu, L, Asano, Y, Hashizume, S, Aida, J, Imaeda, T, Okamoto, R, Jennings, A.J, Michinom, M, Kuroita, T, Stamford, A, Gao, P, Meinke, P, Glickman, J.F, Patel, D.J, Tuschl, T.
登録日2018-09-23
公開日2019-05-29
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Development of human cGAS-specific small-molecule inhibitors for repression of dsDNA-triggered interferon expression.
Nat Commun, 10, 2019
6NIF
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crystal structure of human REV7-RAN complex
分子名称: hREV7, GTP-binding nuclear protein Ran, hREV3 fusion
著者Wang, X, Pertz, L, Hua, D.P, Zhang, T.Q, Listovsky, T, Xie, W.
登録日2018-12-27
公開日2019-09-11
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.002 Å)
主引用文献REV7 has a dynamic adaptor region to accommodate small GTPase RAN/ShigellaIpaB ligands, and its activity is regulated by the RanGTP/GDP switch.
J.Biol.Chem., 294, 2019
4GK0
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Crystal structure of human Rev3-Rev7-Rev1 complex
分子名称: DNA polymerase zeta catalytic subunit, DNA repair protein REV1, Mitotic spindle assembly checkpoint protein MAD2B
著者Tao, J, Min, X, Wei, X.
登録日2012-08-10
公開日2013-03-13
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural insights into the assembly of human translesion polymerase complexes
Protein Cell, 3, 2012

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