7EZG

The structure of the human METTL6 enzyme in complex with SAH

Summary for 7EZG

• Entry DOI: 10.2210/pdb7ezg/pdb
• Descriptor: tRNA N(3)-methylcytidine methyltransferase METTL6, S-ADENOSYL-L-HOMOCYSTEINE (3 entities in total)
• Functional Keywords: m3c, trna modifications, cocrystal, mettl6, toxin, methyltransferase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 36170.20

Authors

Xie, W.,Chen, R.,Zhou, J.,Liu, L. (deposition date: 2021-06-01, release date: 2022-01-12, Last modification date: 2023-11-29)

• Primary citation: Chen, R.,Zhou, J.,Liu, L.,Mao, X.L.,Zhou, X.,Xie, W.; Crystal structure of human METTL6, the m 3 C methyltransferase.; Commun Biol, 4:1361-1361, 2021; PubMed: 34862464; DOI: 10.1038/s42003-021-02890-9

Experimental method

X-RAY DIFFRACTION (1.9 Å)