7EZG
The structure of the human METTL6 enzyme in complex with SAH
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | tRNA N(3)-methylcytidine methyltransferase METTL6 | polymer | 305 | 35785.8 | 1 | UniProt (Q8TCB7) Pfam (PF08242) In PDB | Homo sapiens (Human) | Methyltransferase-like protein 6 |
2 | A | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 1 | Chemie (SAH) | |||
3 | water | water | 18.0 | 170 | Chemie (HOH) |
Sequence modifications
A: 1 - 284 (UniProt: Q8TCB7)
PDB | External Database | Details |
---|---|---|
Met -20 | - | initiating methionine |
Gly -19 | - | expression tag |
Ser -18 | - | expression tag |
Ser -17 | - | expression tag |
His -16 | - | expression tag |
His -15 | - | expression tag |
His -14 | - | expression tag |
His -13 | - | expression tag |
His -12 | - | expression tag |
His -11 | - | expression tag |
His -10 | - | expression tag |
His -9 | - | expression tag |
Leu -8 | - | expression tag |
Glu -7 | - | expression tag |
Val -6 | - | expression tag |
Leu -5 | - | expression tag |
Phe -4 | - | expression tag |
Gln -3 | - | expression tag |
Gly -2 | - | expression tag |
Pro -1 | - | expression tag |
His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 35785.8 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 384.4 | |
All* | Total formula weight | 36170.2 |