7EZG

The structure of the human METTL6 enzyme in complex with SAH

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005737	cellular_component	cytoplasm
A	0006400	biological_process	tRNA modification
A	0008033	biological_process	tRNA processing
A	0008168	molecular_function	methyltransferase activity
A	0008173	molecular_function	RNA methyltransferase activity
A	0008757	molecular_function	S-adenosylmethionine-dependent methyltransferase activity
A	0019899	molecular_function	enzyme binding
A	0030488	biological_process	tRNA methylation
A	0032259	biological_process	methylation
A	0052735	molecular_function	tRNA (cytidine-3-)-methyltransferase activity

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	7
Details	BINDING: BINDING => ECO:0000269|PubMed:34922197, ECO:0007744|PDB:7F1E

Chain	Residue	Details
A	TRP45
A	TYR49
A	GLY87
A	ASP110
A	ASP136
A	LEU137
A	ILE157

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site_id	SWS_FT_FI2
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269|PubMed:34862464, ECO:0007744|PDB:7EZG

Chain	Residue	Details
A	HIS61
A	GLU85

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