6UZH
 
 | | Cryo-EM structure of mechanosensitive channel MscS reconstituted into peptidiscs | | 分子名称: | Small-conductance mechanosensitive channel | | 著者 | Angiulli, G, Walz, T, Dhupar, H.S, Suzuki, H, Wason, I.S, Duong Van Hoa, F. | | 登録日 | 2019-11-15 | | 公開日 | 2020-03-04 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | New approach for membrane protein reconstitution into peptidiscs and basis for their adaptability to different proteins.
Elife, 9, 2020
|
|
6UZ2
 | | Cryo-EM structure of nucleotide-free MsbA reconstituted into peptidiscs, conformation 1 | | 分子名称: | Lipid A export ATP-binding/permease protein MsbA | | 著者 | Angiulli, G, Walz, T, Dhupar, H.S, Suzuki, H, Wason, I.S, Duong Van Hoa, F. | | 登録日 | 2019-11-14 | | 公開日 | 2020-03-04 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | New approach for membrane protein reconstitution into peptidiscs and basis for their adaptability to different proteins.
Elife, 9, 2020
|
|
6URO
 | | Cryo-EM structure of human CPSF160-WDR33-CPSF30-PAS RNA-CstF77 complex | | 分子名称: | Cleavage and polyadenylation specificity factor subunit 1, Cleavage and polyadenylation specificity factor subunit 4, Cleavage stimulation factor subunit 3, ... | | 著者 | Sun, Y, Zhang, Y, Walz, T, Tong, L. | | 登録日 | 2019-10-23 | | 公開日 | 2019-11-27 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structural Insights into the Human Pre-mRNA 3'-End Processing Machinery.
Mol.Cell, 77, 2020
|
|
6V4X
 | | Cryo-EM structure of an active human histone pre-mRNA 3'-end processing machinery at 3.2 Angstrom resolution | | 分子名称: | Cleavage and polyadenylation specificity factor subunit 2, Cleavage and polyadenylation specificity factor subunit 3, Small nuclear ribonucleoprotein E, ... | | 著者 | Sun, Y, Zhang, Y, Walz, T, Tong, L. | | 登録日 | 2019-12-02 | | 公開日 | 2020-02-19 | | 最終更新日 | 2022-03-16 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structure of an active human histone pre-mRNA 3'-end processing machinery.
Science, 367, 2020
|
|
3J6J
 | | 3.6 Angstrom resolution MAVS filament generated from helical reconstruction | | 分子名称: | Mitochondrial antiviral-signaling protein | | 著者 | Wu, B, Peisley, A, Li, Z, Egelman, E, Walz, T, Penczek, P, Hur, S. | | 登録日 | 2014-03-13 | | 公開日 | 2014-07-30 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (3.64 Å) | | 主引用文献 | Molecular Imprinting as a Signal-Activation Mechanism of the Viral RNA Sensor RIG-I.
Mol.Cell, 55, 2014
|
|
3M9I
 | |
3OV9
 | | Structure of the Nucleoprotein from Rift Valley Fever Virus | | 分子名称: | NITRITE ION, Nucleoprotein, SODIUM ION | | 著者 | Ferron, F, Danek, E.I, Li, Z, Luo, D, Wong, Y.H, Coutard, B, Lantez, V, Charrel, R, Canard, B, Walz, T, Lescar, J. | | 登録日 | 2010-09-16 | | 公開日 | 2011-05-25 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | The hexamer structure of Rift Valley fever virus nucleoprotein suggests a mechanism for its assembly into ribonucleoprotein complexes
Plos Pathog., 7, 2011
|
|
3OUO
 | | Structure of the Nucleoprotein from Rift Valley Fever Virus | | 分子名称: | NITRITE ION, Nucleoprotein | | 著者 | Ferron, F, Danek, E.I, Li, Z, Luo, D, Wong, Y.H, Coutard, B, Lantez, V, Charrel, R, Canard, B, Walz, T, Lescar, J. | | 登録日 | 2010-09-15 | | 公開日 | 2011-05-25 | | 最終更新日 | 2013-08-28 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | The hexamer structure of Rift Valley fever virus nucleoprotein suggests a mechanism for its assembly into ribonucleoprotein complexes
Plos Pathog., 7, 2011
|
|
2D57
 | | Double layered 2D crystal structure of AQUAPORIN-4 (AQP4M23) at 3.2 a resolution by electron crystallography | | 分子名称: | Aquaporin-4 | | 著者 | Hiroaki, Y, Tani, K, Kamegawa, A, Gyobu, N, Nishikawa, K, Suzuki, H, Walz, T, Sasaki, S, Mitsuoka, K, Kimura, K, Mizoguchi, A, Fujiyoshi, Y. | | 登録日 | 2005-10-29 | | 公開日 | 2006-01-31 | | 最終更新日 | 2023-11-08 | | 実験手法 | ELECTRON CRYSTALLOGRAPHY (3.2 Å) | | 主引用文献 | Implications of the Aquaporin-4 Structure on Array Formation and Cell Adhesion
J.Mol.Biol., 355, 2005
|
|
6MK0
 | | Integrin AlphaVBeta3 ectodomain bound to antagonist TDI-4161 | | 分子名称: | (2S)-2-[(1,3-benzothiazole-2-carbonyl)amino]-4-{[5-(1,8-naphthyridin-2-yl)pentanoyl]amino}butanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | van Agthoven, J, Arnaout, M.A. | | 登録日 | 2018-09-24 | | 公開日 | 2019-09-25 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (3.005 Å) | | 主引用文献 | Novel Pure alphaVbeta3 Integrin Antagonists That Do Not Induce Receptor Extension, Prime the Receptor, or Enhance Angiogenesis at Low Concentrations
Acs Pharmacol Transl Sci, 2, 2019
|
|
5K8D
 | | Crystal structure of rFVIIIFc | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, COPPER (II) ION, ... | | 著者 | Leksa, N, Quan, C. | | 登録日 | 2016-05-29 | | 公開日 | 2017-06-14 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (4.19 Å) | | 主引用文献 | The structural basis for the functional comparability of factor VIII and the long-acting variant recombinant factor VIII Fc fusion protein.
J. Thromb. Haemost., 15, 2017
|
|
8SOK
 | |
8SOJ
 | |
4GL2
 | | Structural Basis for dsRNA duplex backbone recognition by MDA5 | | 分子名称: | Interferon-induced helicase C domain-containing protein 1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, RNA (5'-R(*AP*UP*CP*CP*GP*CP*GP*GP*CP*CP*CP*U)-3'), ... | | 著者 | Wu, B, Hur, S. | | 登録日 | 2012-08-13 | | 公開日 | 2013-01-09 | | 最終更新日 | 2013-02-06 | | 実験手法 | X-RAY DIFFRACTION (3.557 Å) | | 主引用文献 | Structural Basis for dsRNA Recognition, Filament Formation, and Antiviral Signal Activation by MDA5.
Cell(Cambridge,Mass.), 152, 2013
|
|
2WGH
 | | Human Ribonucleotide reductase R1 subunit (RRM1) in complex with dATP and Mg. | | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ... | | 著者 | Welin, R.M, Moche, M, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Karlberg, T, Kragh-Nielsen, T, Kotzsch, A, Kotenyova, T, Nyman, T, Persson, C, Sagemark, J, Schueler, H, Schutz, P, Siponen, M.I, Svensson, L, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Weigelt, J, Wisniewska, M, Nordlund, P. | | 登録日 | 2009-04-19 | | 公開日 | 2009-05-05 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural Basis for Allosteric Regulation of Human Ribonucleotide Reductase by Nucleotide-Induced Oligomerization.
Nat.Struct.Mol.Biol., 18, 2011
|
|
3V4P
 | | crystal structure of a4b7 headpiece complexed with Fab ACT-1 | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | 著者 | Yu, Y, Zhu, J, Springer, T.A. | | 登録日 | 2011-12-15 | | 公開日 | 2012-01-11 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | | 主引用文献 | Structural specializations of a4b7, an Integrin that Mediates Rolling Adhesion
J.Cell Biol., 196, 2012
|
|
3RJR
 | | Crystal Structure of pro-TGF beta 1 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Transforming growth factor beta-1 | | 著者 | Zhu, J.H, Shi, M.L, Springer, T.A. | | 登録日 | 2011-04-15 | | 公開日 | 2011-06-15 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | | 主引用文献 | Latent TGF-Beta structure and activation
Nature, 474, 2011
|
|
3V4V
 | | crystal structure of a4b7 headpiece complexed with Fab ACT-1 and RO0505376 | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | 著者 | Yu, Y, Zhu, J, Springer, T.A. | | 登録日 | 2011-12-15 | | 公開日 | 2012-01-11 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structural specializations of a4b7, an Integrin that Mediates Rolling Adhesion
J.Cell Biol., 196, 2012
|
|
6CO3
 | | aducanumab abeta complex | | 分子名称: | ALA-GLU-PHE-ARG-HIS-ASP, Fab heavy chain, Fab light chain, ... | | 著者 | Arndt, J.W. | | 登録日 | 2018-03-10 | | 公開日 | 2018-05-02 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.384 Å) | | 主引用文献 | Structural and kinetic basis for the selectivity of aducanumab for aggregated forms of amyloid-beta.
Sci Rep, 8, 2018
|
|
6CNR
 | | aducanumab apo Fab | | 分子名称: | Aducanumab heavy chain, Aducanumab light chain, SULFATE ION | | 著者 | Arndt, J.W. | | 登録日 | 2018-03-08 | | 公開日 | 2018-05-02 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | | 主引用文献 | Structural and kinetic basis for the selectivity of aducanumab for aggregated forms of amyloid-beta.
Sci Rep, 8, 2018
|
|
2Q06
 | | Crystal structure of Influenza A Virus H5N1 Nucleoprotein | | 分子名称: | Nucleoprotein | | 著者 | Ng, A.K.L, Zhang, H, Tan, K, Wang, J, Shaw, P.C. | | 登録日 | 2007-05-21 | | 公開日 | 2008-05-27 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Structure of the influenza virus A H5N1 nucleoprotein: implications for RNA binding, oligomerization, and vaccine design.
Faseb J., 22, 2008
|
|
8FWF
 | | Crystal structure of Apo form Fab235 | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, CHLORIDE ION, ... | | 著者 | Tan, K, Kim, M, Reinherz, E.L. | | 登録日 | 2023-01-21 | | 公開日 | 2023-10-11 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | | 主引用文献 | Inadequate structural constraint on Fab approach rather than paratope elicitation limits HIV-1 MPER vaccine utility.
Nat Commun, 14, 2023
|
|
8FZ2
 | | Crystal structure of Fab460 in complex with MPER peptide | | 分子名称: | Fab460, H chain, L chain, ... | | 著者 | Tan, K, Kim, M, Reinherz, E.L. | | 登録日 | 2023-01-27 | | 公開日 | 2023-10-11 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Inadequate structural constraint on Fab approach rather than paratope elicitation limits HIV-1 MPER vaccine utility.
Nat Commun, 14, 2023
|
|
8FXJ
 | | Crystal structure of Fab460 | | 分子名称: | ACETATE ION, CHLORIDE ION, Fab460, ... | | 著者 | Tan, K, Kim, M, Reinherz, E.L. | | 登録日 | 2023-01-24 | | 公開日 | 2023-10-11 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Inadequate structural constraint on Fab approach rather than paratope elicitation limits HIV-1 MPER vaccine utility.
Nat Commun, 14, 2023
|
|
8FYM
 | | Crystal structure of Fab235 in complex with MPER peptide | | 分子名称: | ALA-SER-LEU-TRP-ASN-TRP-PHE-ASN-ILE-THR-ASN-TRP-LEU-TRP-TYR-ILE-LYS-LYS-LYS, CHLORIDE ION, Fab235, ... | | 著者 | Tan, K, Kim, M, Reinherz, E.L. | | 登録日 | 2023-01-26 | | 公開日 | 2023-10-11 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Inadequate structural constraint on Fab approach rather than paratope elicitation limits HIV-1 MPER vaccine utility.
Nat Commun, 14, 2023
|
|
