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8HF6
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BU of 8hf6 by Molmil
Cryo-EM structure of nucleotide-bound ComA E647Q mutant
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Competence factor transporting ATP-binding protein/permease ComA
Authors:Yu, L, Xin, X, Min, L.
Deposit date:2022-11-09
Release date:2023-10-04
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural basis of peptide secretion for Quorum sensing by ComA.
Nat Commun, 14, 2023
8HF7
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BU of 8hf7 by Molmil
Cryo-EM structure of ComA bound to its mature substrate CSP peptide
Descriptor: Competence factor transporting ATP-binding protein/permease ComA, Competence-stimulating peptide type 1
Authors:Yu, L, Xin, X, Min, L.
Deposit date:2022-11-09
Release date:2023-10-11
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural basis of peptide secretion for Quorum sensing by ComA.
Nat Commun, 14, 2023
4EYC
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BU of 4eyc by Molmil
Crystal structure of the cathelin-like domain of human cathelicidin LL-37 (hCLD)
Descriptor: Cathelicidin antimicrobial peptide
Authors:Pazgier, M, Pozharski, E, Toth, E, Lu, W.
Deposit date:2012-05-01
Release date:2013-02-27
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural and Functional Analysis of the Pro-Domain of Human Cathelicidin, LL-37.
Biochemistry, 52, 2013
6KJ6
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BU of 6kj6 by Molmil
cryo-EM structure of Escherichia coli Crl transcription activation complex
Descriptor: DNA (51-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Xu, J, Zhang, Y.
Deposit date:2019-07-21
Release date:2020-01-01
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Crl activates transcription by stabilizing active conformation of the master stress transcription initiation factor.
Elife, 8, 2019
7VKR
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BU of 7vkr by Molmil
Crystal structure of D. melanogaster SAMTOR in complex with SAM
Descriptor: CITRIC ACID, S-ADENOSYLMETHIONINE, S-adenosylmethionine sensor upstream of mTORC1
Authors:Tang, X, Zhang, T, Ding, J.
Deposit date:2021-09-30
Release date:2022-07-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Molecular mechanism of S -adenosylmethionine sensing by SAMTOR in mTORC1 signaling.
Sci Adv, 8, 2022
7VKK
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BU of 7vkk by Molmil
Crystal structure of D. melanogaster SAMTOR V66W/E67P mutant
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, S-adenosylmethionine sensor upstream of mTORC1, SULFATE ION
Authors:Zhang, T, Ding, J.
Deposit date:2021-09-30
Release date:2022-07-20
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.55 Å)
Cite:Molecular mechanism of S -adenosylmethionine sensing by SAMTOR in mTORC1 signaling.
Sci Adv, 8, 2022
7VKQ
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BU of 7vkq by Molmil
Crystal structure of D. melanogaster SAMTOR in the SAH bound form
Descriptor: S-ADENOSYL-L-HOMOCYSTEINE, S-adenosylmethionine sensor upstream of mTORC1
Authors:Tang, X, Zhang, T, Ding, J.
Deposit date:2021-09-30
Release date:2022-07-20
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.094 Å)
Cite:Molecular mechanism of S -adenosylmethionine sensing by SAMTOR in mTORC1 signaling.
Sci Adv, 8, 2022
5FJB
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BU of 5fjb by Molmil
Cyclophilin A Stabilize HIV-1 Capsid through a Novel Non- canonical Binding Site
Descriptor: GAG POLYPROTEIN, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A
Authors:Liu, C, Perilla, J.R, Ning, J, Lu, M, Hou, G, Ramalhu, R, Bedwell, G.J, Ahn, J, Shi, J, Gronenborn, A.M, Prevelige Jr, P.E, Rousso, I, Aiken, C, Polenova, T, Schulten, K, Zhang, P.
Deposit date:2015-10-07
Release date:2016-03-16
Last modified:2017-08-23
Method:ELECTRON MICROSCOPY (9 Å)
Cite:Cyclophilin a Stabilizes the HIV-1 Capsid Through a Novel Non-Canonical Binding Site.
Nat.Commun., 7, 2016
6J0D
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BU of 6j0d by Molmil
Crystal structure of OsSUF4
Descriptor: ZINC ION, transcription factor
Authors:Wang, B, Luo, Q.
Deposit date:2018-12-24
Release date:2019-11-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The transcription factor OsSUF4 interacts with SDG725 in promoting H3K36me3 establishment.
Nat Commun, 10, 2019
6LDI
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BU of 6ldi by Molmil
The cryo-EM structure of E. coli CueR transcription activation complex
Descriptor: DNA (50-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Fang, C.L, Zhang, Y.
Deposit date:2019-11-21
Release date:2020-09-30
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.69 Å)
Cite:CueR activates transcription through a DNA distortion mechanism.
Nat.Chem.Biol., 17, 2021
5Y0A
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BU of 5y0a by Molmil
Cryo-EM structure of zika virus complexed with Fab of ZKA190 at pH 8.0 and 37 celsius degree
Descriptor: protein E, variable region of Fab ZKA190 heavy chain, variable region of Fab ZKA190 light chain
Authors:Wang, J.Q, Lok, S.M.
Deposit date:2017-07-15
Release date:2017-10-04
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (22 Å)
Cite:A Human Bi-specific Antibody against Zika Virus with High Therapeutic Potential.
Cell, 171, 2017
7WUT
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BU of 7wut by Molmil
CryoEM structure of stable sNS1 tetramer
Descriptor: Core protein
Authors:Shu, B, Ooi, J.S.G, Lok, S.M.
Deposit date:2022-02-09
Release date:2022-12-21
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:CryoEM structures of the multimeric secreted NS1, a major factor for dengue hemorrhagic fever.
Nat Commun, 13, 2022
7WUV
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BU of 7wuv by Molmil
CryoEM structure of sNS1 hexamer
Descriptor: Core protein
Authors:Shu, B, Ooi, J.S.G, Lok, S.M.
Deposit date:2022-02-09
Release date:2022-12-21
Method:ELECTRON MICROSCOPY (8 Å)
Cite:CryoEM structures of the multimeric secreted NS1, a major factor for dengue hemorrhagic fever.
Nat Commun, 13, 2022
7WUR
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BU of 7wur by Molmil
CryoEM structure of sNS1 complexed with Fab5E3
Descriptor: Core protein, Fab 5E3 Heavy Chain, Fab 5E3 Light Chain
Authors:Shu, B, Lok, S.M.
Deposit date:2022-02-09
Release date:2022-12-21
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:CryoEM structures of the multimeric secreted NS1, a major factor for dengue hemorrhagic fever.
Nat Commun, 13, 2022
7WUS
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BU of 7wus by Molmil
CryoEM structure of a dimer of loose sNS1 tetramer
Descriptor: Core protein
Authors:Shu, B, Lok, S.M.
Deposit date:2022-02-09
Release date:2022-12-21
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:CryoEM structures of the multimeric secreted NS1, a major factor for dengue hemorrhagic fever.
Nat Commun, 13, 2022
7WUU
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BU of 7wuu by Molmil
CryoEM structure of loose sNS1 tetramer
Descriptor: Core protein
Authors:Shu, B, Lok, S.M.
Deposit date:2022-02-09
Release date:2022-12-21
Last modified:2023-08-02
Method:ELECTRON MICROSCOPY (8.3 Å)
Cite:CryoEM structures of the multimeric secreted NS1, a major factor for dengue hemorrhagic fever.
Nat Commun, 13, 2022
6A5F
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BU of 6a5f by Molmil
The structure of [4+2] and [6+4] cyclase in the biosynthetic pathway of nargenicin
Descriptor: NgnD
Authors:Zhang, B, Ge, H.M.
Deposit date:2018-06-23
Release date:2019-02-06
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Enzyme-catalysed [6+4] cycloadditions in the biosynthesis of natural products.
Nature, 568, 2019
6A5G
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BU of 6a5g by Molmil
The structure of [4+2] and [6+4] cyclase in the biosynthetic pathway of streptoseomycin
Descriptor: [4+2] and [4+6] cyclase StmD
Authors:Zhang, B, Ge, H.M.
Deposit date:2018-06-23
Release date:2019-02-06
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Enzyme-catalysed [6+4] cycloadditions in the biosynthesis of natural products.
Nature, 568, 2019
5H32
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BU of 5h32 by Molmil
Cryo-EM structure of zika virus complexed with Fab C10 at pH 5.0
Descriptor: C10 IgG heavy chain variable region, C10 IgG light chain variable region, structural protein E
Authors:Zhang, S, Kostyuchenko, V, Ng, T.-S, Lok, S.-M.
Deposit date:2016-10-20
Release date:2016-11-30
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (12 Å)
Cite:Neutralization mechanism of a highly potent antibody against Zika virus
Nat Commun, 7, 2016
5H30
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BU of 5h30 by Molmil
Cryo-EM structure of zika virus complexed with Fab C10 at pH 6.5
Descriptor: IgG C10 heavy chain, IgG C10 light chain, structural protein E, ...
Authors:Zhang, S, Kostyuchenko, V, Ng, T.-S, Lok, S.-M.
Deposit date:2016-10-19
Release date:2016-11-30
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Neutralization mechanism of a highly potent antibody against Zika virus
Nat Commun, 7, 2016
6AY9
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BU of 6ay9 by Molmil
Structure of the native full-length HIV-1 capsid protein in complex with CPSF6 peptide
Descriptor: CHLORIDE ION, Cleavage and polyadenylation specificity factor subunit 6, HIV-1 capsid protein, ...
Authors:Gres, A.T, Kirby, K.A, Sarafianos, S.G.
Deposit date:2017-09-07
Release date:2018-09-12
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Multidisciplinary studies with mutated HIV-1 capsid proteins reveal structural mechanisms of lattice stabilization.
Nat Commun, 14, 2023
6B2K
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BU of 6b2k by Molmil
E45A/R132T mutant of HIV-1 capsid protein
Descriptor: CHLORIDE ION, HIV-1 capsid protein, IODIDE ION
Authors:Gres, A.T, Kirby, K.A, Sarafianos, S.G.
Deposit date:2017-09-20
Release date:2018-09-26
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:Multidisciplinary studies with mutated HIV-1 capsid proteins reveal structural mechanisms of lattice stabilization.
Nat Commun, 14, 2023
6AYA
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BU of 6aya by Molmil
Structure of the native full-length HIV-1 capsid protein in complex with Nup153 peptide
Descriptor: CHLORIDE ION, HIV-1 capsid protein, IODIDE ION, ...
Authors:Gres, A.T, Kirby, K.A, Sarafianos, S.G.
Deposit date:2017-09-07
Release date:2018-09-12
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Multidisciplinary studies with mutated HIV-1 capsid proteins reveal structural mechanisms of lattice stabilization.
Nat Commun, 14, 2023
6B2J
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BU of 6b2j by Molmil
E45A mutant of HIV-1 capsid protein (other crystal form)
Descriptor: CHLORIDE ION, HIV-1 capsid protein, IODIDE ION
Authors:Gres, A.T, Kirby, K.A, Sarafianos, S.G.
Deposit date:2017-09-20
Release date:2018-09-26
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Multidisciplinary studies with mutated HIV-1 capsid proteins reveal structural mechanisms of lattice stabilization.
Nat Commun, 14, 2023
6B2I
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BU of 6b2i by Molmil
E45A mutant of the HIV-1 capsid protein
Descriptor: CHLORIDE ION, HIV-1 capsid protein, IODIDE ION
Authors:Gres, A.T, Kirby, K.A, Sarafianos, S.G.
Deposit date:2017-09-20
Release date:2018-09-26
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Multidisciplinary studies with mutated HIV-1 capsid proteins reveal structural mechanisms of lattice stabilization.
Nat Commun, 14, 2023

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數據於2024-05-29公開中

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