6AY9

Structure of the native full-length HIV-1 capsid protein in complex with CPSF6 peptide

Summary for 6AY9

• Entry DOI: 10.2210/pdb6ay9/pdb
• Related: 4XFX
• Descriptor: HIV-1 capsid protein, Cleavage and polyadenylation specificity factor subunit 6, IODIDE ION, ... (5 entities in total)
• Functional Keywords: hiv-1 capsid protein, hexamer, cpsf6 complex, viral protein
• Biological source: Human immunodeficiency virus 1; More
• Total number of polymer chains: 2
• Total formula weight: 27817.13

Authors

Gres, A.T.,Kirby, K.A.,Sarafianos, S.G. (deposition date: 2017-09-07, release date: 2018-09-12, Last modification date: 2023-10-04)

• Primary citation: Gres, A.T.,Kirby, K.A.,McFadden, W.M.,Du, H.,Liu, D.,Xu, C.,Bryer, A.J.,Perilla, J.R.,Shi, J.,Aiken, C.,Fu, X.,Zhang, P.,Francis, A.C.,Melikyan, G.B.,Sarafianos, S.G.; Multidisciplinary studies with mutated HIV-1 capsid proteins reveal structural mechanisms of lattice stabilization.; Nat Commun, 14:5614-5614, 2023; PubMed: 37699872; DOI: 10.1038/s41467-023-41197-7

Experimental method

X-RAY DIFFRACTION (2.5 Å)