7RPU
 
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7RPT
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5WEQ
 | | The crystal structure of a MR78 mutant | | Descriptor: | MR78 mutant Fab heavy chain, MR78 mutant light chain | | Authors: | Dong, J, Williamson, L.E, Crowe, J.E. | | Deposit date: | 2017-07-10 | | Release date: | 2018-04-25 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Role of Non-local Interactions between CDR Loops in Binding Affinity of MR78 Antibody to Marburg Virus Glycoprotein.
Structure, 25, 2017
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1NAK
 | | IGG1 FAB FRAGMENT (83.1) COMPLEX WITH 16-RESIDUE PEPTIDE (RESIDUES 304-321 OF HIV-1 GP120 (MN ISOLATE)) | | Descriptor: | Fab 83.1 - heavy chain, Fab 83.1 - light chain, Peptide MP1 | | Authors: | Stanfield, R.L, Ghiara, J.B, Saphire, E.O, Profy, A.T, Wilson, I.A. | | Deposit date: | 2002-11-27 | | Release date: | 2003-11-18 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2.57 Å) | | Cite: | Recurring conformation of the human immunodeficiency virus type 1 gp120 V3 loop.
Virology, 315, 2003
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6OAF
 | | Sudan virus nucleoprotein core domain in complex with VP35 chaperoning peptide | | Descriptor: | Polymerase cofactor VP35,Nucleoprotein | | Authors: | Landeras-Bueno, S, Oda, S, Norris, M.J, Li Salie, Z, Ollmann Saphire, E. | | Deposit date: | 2019-03-15 | | Release date: | 2019-08-07 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Sudan Ebolavirus VP35-NP Crystal Structure Reveals a Potential Target for Pan-Filovirus Treatment.
Mbio, 10, 2019
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6UYE
 | | EBOV GPdMuc Makona bound to rEBOV-548 Fab | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody rEBOV-548 Fab, ... | | Authors: | Murin, C.D, Ward, A.B. | | Deposit date: | 2019-11-13 | | Release date: | 2020-03-11 | | Last modified: | 2020-07-29 | | Method: | ELECTRON MICROSCOPY (3.96 Å) | | Cite: | Analysis of a Therapeutic Antibody Cocktail Reveals Determinants for Cooperative and Broad Ebolavirus Neutralization.
Immunity, 52, 2020
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4CSG
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4D9O
 | | Structure of ebolavirus protein VP24 from Reston | | Descriptor: | Membrane-associated protein VP24 | | Authors: | Zhang, A.P.P. | | Deposit date: | 2012-01-11 | | Release date: | 2012-04-18 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | The ebola virus interferon antagonist VP24 directly binds STAT1 and has a novel, pyramidal fold
Plos Pathog., 8, 2012
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7UL7
 | | Lineage I (Pinneo) Lassa virus glycoprotein bound to 18.5C-M30 Fab | | Descriptor: | 18.5C-M30 Fab Heavy Chain, 18.5C-M30 Fab Light Chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Buck, T.K, Enriquez, A.S, Hastie, K.M. | | Deposit date: | 2022-04-04 | | Release date: | 2022-06-15 | | Last modified: | 2022-09-07 | | Method: | ELECTRON MICROSCOPY (3.59 Å) | | Cite: | Neutralizing Antibodies against Lassa Virus Lineage I.
Mbio, 13, 2022
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4CSF
 | | Structural insights into Toscana virus RNA encapsidation | | Descriptor: | NUCLEOPROTEIN, RNA (5'-R(*UP*GP*UP*GP*UP*UP*UP*CP*UP)-3') | | Authors: | Olal, D, Daumke, O. | | Deposit date: | 2014-03-07 | | Release date: | 2014-04-09 | | Last modified: | 2019-10-16 | | Method: | X-RAY DIFFRACTION (2.598 Å) | | Cite: | Structural Insights Into RNA Encapsidation and Helical Assembly of the Toscana Virus Nucleoprotein.
Nucleic Acids Res., 42, 2014
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7JZT
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7JZJ
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8B1P
 | | Crystal structure of SUDV VP40 CCS mutant | | Descriptor: | Matrix protein VP40 | | Authors: | Werner, A.-D, Becker, S. | | Deposit date: | 2022-09-11 | | Release date: | 2023-06-21 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | The C-terminus of Sudan ebolavirus VP40 contains a functionally important CX n C motif, a target for redox modifications.
Structure, 31, 2023
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8B1O
 | | Crystal structure of SUDV VP40 C314S mutant | | Descriptor: | Matrix protein VP40 | | Authors: | Werner, A.-D, Becker, S. | | Deposit date: | 2022-09-11 | | Release date: | 2023-06-21 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | The C-terminus of Sudan ebolavirus VP40 contains a functionally important CX n C motif, a target for redox modifications.
Structure, 31, 2023
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5JRP
 | | crystal structure of monoclonal antibody MR78 Fab | | Descriptor: | SODIUM ION, marberg virus monoclonal antibody MR78 Fab heavy chain, marberg virus monoclonal antibody MR78 Fab light chain | | Authors: | Dong, J, Crowe, J. | | Deposit date: | 2016-05-06 | | Release date: | 2017-11-08 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Role of Non-local Interactions between CDR Loops in Binding Affinity of MR78 Antibody to Marburg Virus Glycoprotein.
Structure, 25, 2017
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6NUT
 | | Ebola virus nucleoprotein - RNA complex | | Descriptor: | Nucleoprotein, RNA (5'-R(P*AP*AP*AP*AP*AP*A)-3') | | Authors: | Kirchdoerfer, R.N, Ward, A.B. | | Deposit date: | 2019-02-01 | | Release date: | 2019-05-01 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Cryo-EM structure of the Ebola virus nucleoprotein-RNA complex.
Acta Crystallogr.,Sect.F, 75, 2019
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6PCI
 | | EBOV GPdMuc (Makona) in complex with rEBOV-520 and rEBOV-548 Fabs | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Virion spike glycoprotein, Virion spike glycoprotein,Virion spike glycoprotein,Ebola Virus (Makona) GP2, ... | | Authors: | Ward, A.B, Murin, C.D, Alkutkar, T. | | Deposit date: | 2019-06-17 | | Release date: | 2020-03-11 | | Last modified: | 2020-07-29 | | Method: | ELECTRON MICROSCOPY (4.12 Å) | | Cite: | Analysis of a Therapeutic Antibody Cocktail Reveals Determinants for Cooperative and Broad Ebolavirus Neutralization.
Immunity, 52, 2020
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7S8H
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7TYV
 | | Structure of Lassa Virus glycoprotein (Josiah) bound to Fab 25.10C | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 25.10C Fab Heavy Chain, ... | | Authors: | Enriquez, A.S, Hastie, K.M. | | Deposit date: | 2022-02-14 | | Release date: | 2022-06-01 | | Last modified: | 2022-06-15 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Delineating the mechanism of anti-Lassa virus GPC-A neutralizing antibodies.
Cell Rep, 39, 2022
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7UDS
 | | Structure of lineage I (Pinneo) Lassa virus glycoprotein bound to Fab 25.10C | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 25.10C Fab Heavy Chain, ... | | Authors: | Buck, T.K, Enriquez, A.E, Hastie, K.M. | | Deposit date: | 2022-03-20 | | Release date: | 2022-06-15 | | Last modified: | 2022-09-07 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Neutralizing Antibodies against Lassa Virus Lineage I.
Mbio, 13, 2022
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7S8G
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7T67
 | | SARS-CoV-2 S (Spike Glycoprotein) D614G with One(1) RBD Up | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | | Authors: | Byrne, P.O, McLellan, J.S. | | Deposit date: | 2021-12-13 | | Release date: | 2022-08-24 | | Last modified: | 2023-03-08 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | IgG-like bispecific antibodies with potent and synergistic neutralization against circulating SARS-CoV-2 variants of concern.
Nat Commun, 13, 2022
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7T3M
 | | SARS-CoV-2 S (Spike Glycoprotein) D614G with Three (3) RBDs Up, Bound to Antibody 2-7 scFv, composite map | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody 2-7 scFv, ... | | Authors: | Byrne, P.O, McLellan, J.S. | | Deposit date: | 2021-12-08 | | Release date: | 2022-08-24 | | Last modified: | 2023-03-08 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | IgG-like bispecific antibodies with potent and synergistic neutralization against circulating SARS-CoV-2 variants of concern.
Nat Commun, 13, 2022
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3V7O
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3VNF
 | | Structure of the ebolavirus protein VP24 from Sudan | | Descriptor: | Membrane-associated protein VP24 | | Authors: | Zhang, A.P.P. | | Deposit date: | 2012-01-12 | | Release date: | 2012-04-18 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | The ebola virus interferon antagonist VP24 directly binds STAT1 and has a novel, pyramidal fold
Plos Pathog., 8, 2012
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