6UYE

EBOV GPdMuc Makona bound to rEBOV-548 Fab

Summary for 6UYE

• Entry DOI: 10.2210/pdb6uye/pdb
• EMDB information: 20947
• Descriptor: SGP, Virion spike glycoprotein, Antibody rEBOV-548 Fab, heavy chain, ... (8 entities in total)
• Functional Keywords: antibody, ebola, synergy, cross-reactive, therapeutic, viral protein-immune system complex, viral protein/immune system
• Biological source: Ebola virus; More
• Total number of polymer chains: 12
• Total formula weight: 206398.84

Authors

Murin, C.D.,Ward, A.B. (deposition date: 2019-11-13, release date: 2020-03-11, Last modification date: 2020-07-29)

• Primary citation: Gilchuk, P.,Murin, C.D.,Milligan, J.C.,Cross, R.W.,Mire, C.E.,Ilinykh, P.A.,Huang, K.,Kuzmina, N.,Altman, P.X.,Hui, S.,Gunn, B.M.,Bryan, A.L.,Davidson, E.,Doranz, B.J.,Turner, H.L.,Alkutkar, T.,Flinko, R.,Orlandi, C.,Carnahan, R.,Nargi, R.,Bombardi, R.G.,Vodzak, M.E.,Li, S.,Okoli, A.,Ibeawuchi, M.,Ohiaeri, B.,Lewis, G.K.,Alter, G.,Bukreyev, A.,Saphire, E.O.,Geisbert, T.W.,Ward, A.B.,Crowe Jr., J.E.; Analysis of a Therapeutic Antibody Cocktail Reveals Determinants for Cooperative and Broad Ebolavirus Neutralization.; Immunity, 52:388-403.e12, 2020; PubMed: 32023489; DOI: 10.1016/j.immuni.2020.01.001

Experimental method

ELECTRON MICROSCOPY (3.96 Å)