7TYV

Structure of Lassa Virus glycoprotein (Josiah) bound to Fab 25.10C

Summary for 7TYV

• Entry DOI: 10.2210/pdb7tyv/pdb
• EMDB information: 26195
• Descriptor: Glycoprotein G1, 2-acetamido-2-deoxy-beta-D-glucopyranose, 25.10C Fab Heavy Chain, ... (10 entities in total)
• Functional Keywords: surface glycoprotein, antibody fab fragment, antibody-mediated neutralization, epitope-mapping, viral protein, viral protein-immune system complex, viral protein/immune system
• Biological source: Lassa virus; More
• Total number of polymer chains: 12
• Total formula weight: 305334.08

Authors

Enriquez, A.S.,Hastie, K.M. (deposition date: 2022-02-14, release date: 2022-06-01, Last modification date: 2022-06-15)

• Primary citation: Enriquez, A.S.,Buck, T.K.,Li, H.,Norris, M.J.,Moon-Walker, A.,Zandonatti, M.A.,Harkins, S.S.,Robinson, J.E.,Branco, L.M.,Garry, R.F.,Saphire, E.O.,Hastie, K.M.; Delineating the mechanism of anti-Lassa virus GPC-A neutralizing antibodies.; Cell Rep, 39:110841-110841, 2022; PubMed: 35613585; DOI: 10.1016/j.celrep.2022.110841

Experimental method

ELECTRON MICROSCOPY (2.8 Å)