4D9O

Structure of ebolavirus protein VP24 from Reston

Summary for 4D9O

• Entry DOI: 10.2210/pdb4d9o/pdb
• Related: 3VNE 3VNF
• Descriptor: Membrane-associated protein VP24 (2 entities in total)
• Functional Keywords: ebolavirus, interferon antagonist, vp24, stat1, zaire, sudan, reston, vp35, karyopherin alpha, ifn response pathway, viral protein
• Biological source: Reston ebolavirus
• Cellular location: Virion membrane; Peripheral membrane protein (By similarity): Q91DD5
• Total number of polymer chains: 2
• Total formula weight: 53447.78

Authors

Zhang, A.P.P. (deposition date: 2012-01-11, release date: 2012-04-18, Last modification date: 2024-03-20)

• Primary citation: Zhang, A.P.P.,Bornholdt, Z.A.,Liu, T.,Abelson, D.M.,Lee, D.E.,Li, S.,Woods Jr., V.L.,Saphire, E.O.; The ebola virus interferon antagonist VP24 directly binds STAT1 and has a novel, pyramidal fold; Plos Pathog., 8:e1002550-e1002550, 2012; PubMed: 22383882; DOI: 10.1371/journal.ppat.1002550

Experimental method

X-RAY DIFFRACTION (2 Å)