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5CHL
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BU of 5chl by Molmil
Structural basis of H2A.Z recognition by YL1 histone chaperone component of SRCAP/SWR1 chromatin remodeling complex
分子名称: Histone H2A.Z, Vacuolar protein sorting-associated protein 72 homolog
著者Shan, S, Liang, X, Pan, L, Wu, C, Zhou, Z.
登録日2015-07-10
公開日2016-03-09
最終更新日2017-09-27
実験手法X-RAY DIFFRACTION (1.892 Å)
主引用文献Structural basis of H2A.Z recognition by SRCAP chromatin-remodeling subunit YL1
Nat.Struct.Mol.Biol., 23, 2016
7CJB
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BU of 7cjb by Molmil
VHL recognizes hydroxyproline in RIPK1
分子名称: Elongin-B, Elongin-C, GLYCEROL, ...
著者Liu, J, Wang, Y, Pan, L.
登録日2020-07-09
公開日2021-07-14
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献VHL recognizes hydroxyproline in RIPK1
To Be Published
6J56
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BU of 6j56 by Molmil
Crystal structure of Myosin VI CBD in complex with Tom1 MBM
分子名称: Peptide from Target of Myb protein 1, Unconventional myosin-VI
著者Hu, S, Pan, L.
登録日2019-01-10
公開日2019-08-21
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.798 Å)
主引用文献Structure of Myosin VI/Tom1 complex reveals a cargo recognition mode of Myosin VI for tethering.
Nat Commun, 10, 2019
5EP6
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BU of 5ep6 by Molmil
The crystal structure of NAP1 in complex with TBK1
分子名称: 5-azacytidine-induced protein 2, GLYCEROL, Serine/threonine-protein kinase TBK1
著者Li, F, Xie, X, Liu, J, Pan, L.
登録日2015-11-11
公開日2016-09-28
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.451 Å)
主引用文献Structural insights into the interaction and disease mechanism of neurodegenerative disease-associated optineurin and TBK1 proteins.
Nat Commun, 7, 2016
5EOF
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BU of 5eof by Molmil
Crystal structure of OPTN NTD and TBK1 CTD complex
分子名称: Optineurin, Serine/threonine-protein kinase TBK1
著者Li, F, Xie, X, Liu, J, Pan, L.
登録日2015-11-10
公開日2016-09-28
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Structural insights into the interaction and disease mechanism of neurodegenerative disease-associated optineurin and TBK1 proteins.
Nat Commun, 7, 2016
5CX3
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BU of 5cx3 by Molmil
Crystal structure of FYCO1 LIR in complex with LC3A
分子名称: FYVE and coiled-coil domain-containing protein 1, GLYCEROL, Microtubule-associated proteins 1A/1B light chain 3A
著者Cheng, X, Pan, L.
登録日2015-07-28
公開日2016-08-03
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis of FYCO1 and MAP1LC3A interaction reveals a novel binding mode for Atg8-family proteins.
Autophagy, 12, 2016
5EOA
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BU of 5eoa by Molmil
Crystal structure of OPTN E50K mutant and TBK1 complex
分子名称: Optineurin, Serine/threonine-protein kinase TBK1
著者Li, F, Xie, X, Liu, J, Pan, L.
登録日2015-11-10
公開日2016-09-28
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.503 Å)
主引用文献Structural insights into the interaction and disease mechanism of neurodegenerative disease-associated optineurin and TBK1 proteins.
Nat Commun, 7, 2016
5WQ4
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BU of 5wq4 by Molmil
Crystal structure of OPTN and linear diubiquitin complex
分子名称: Optineurin, ubiquitin
著者Li, F, Pan, L.
登録日2016-11-23
公開日2017-12-06
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural insights into the ubiquitin recognition by OPTN (optineurin) and its regulation by TBK1-mediated phosphorylation.
Autophagy, 14, 2018
5X0W
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BU of 5x0w by Molmil
Molecular mechanism for the binding between Sharpin and HOIP
分子名称: E3 ubiquitin-protein ligase RNF31, Sharpin
著者Liu, J, Li, F, Cheng, X, Pan, L.
登録日2017-01-23
公開日2017-10-18
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural Insights into SHARPIN-Mediated Activation of HOIP for the Linear Ubiquitin Chain Assembly
Cell Rep, 21, 2017
4NFT
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BU of 4nft by Molmil
Crystal structure of human lnkH2B-h2A.Z-Anp32e
分子名称: Acidic leucine-rich nuclear phosphoprotein 32 family member E, Histone H2B type 2-E, Histone H2A.Z
著者Shan, S, Pan, L, Mao, Z, Wang, W, Sun, J, Dong, Q, Liang, X, Ding, X, Chen, S, Dai, L, Zhang, Z, Zhu, B, Zhou, Z.
登録日2013-11-01
公開日2014-04-09
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献Anp32e, a higher eukaryotic histone chaperone directs preferential recognition for H2A.Z
Cell Res., 24, 2014
3PZD
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BU of 3pzd by Molmil
Structure of the myosin X MyTH4-FERM/DCC complex
分子名称: GLYCEROL, Myosin-X, Netrin receptor DCC
著者Wei, Z, Yan, J, Pan, L, Zhang, M.
登録日2010-12-14
公開日2011-02-23
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Cargo recognition mechanism of myosin X revealed by the structure of its tail MyTH4-FERM tandem in complex with the DCC P3 domain
Proc.Natl.Acad.Sci.USA, 108, 2011
7V8H
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BU of 7v8h by Molmil
Crystal structure of LRR domain from Shigella flexneri IpaH1.4
分子名称: RING-type E3 ubiquitin transferase
著者Liu, J, Wang, Y, Pan, L.
登録日2021-08-23
公開日2022-03-30
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.46 Å)
主引用文献Mechanistic insights into the subversion of the linear ubiquitin chain assembly complex by the E3 ligase IpaH1.4 of Shigella flexneri.
Proc.Natl.Acad.Sci.USA, 119, 2022
7V8E
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BU of 7v8e by Molmil
Crystal structure of IpaH1.4 LRR domain bound to HOIL-1L UBL domain.
分子名称: RING-type E3 ubiquitin transferase, RanBP-type and C3HC4-type zinc finger-containing protein 1
著者Liu, J, Wang, Y, Pan, L.
登録日2021-08-22
公開日2022-03-30
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Mechanistic insights into the subversion of the linear ubiquitin chain assembly complex by the E3 ligase IpaH1.4 of Shigella flexneri.
Proc.Natl.Acad.Sci.USA, 119, 2022
7V8G
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BU of 7v8g by Molmil
Crystal structure of HOIP RING1 domain bound to IpaH1.4 LRR domain
分子名称: E3 ubiquitin-protein ligase RNF31, RING-type E3 ubiquitin transferase, ZINC ION
著者Liu, J, Wang, Y, Pan, L.
登録日2021-08-23
公開日2022-03-30
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Mechanistic insights into the subversion of the linear ubiquitin chain assembly complex by the E3 ligase IpaH1.4 of Shigella flexneri.
Proc.Natl.Acad.Sci.USA, 119, 2022
7V8F
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BU of 7v8f by Molmil
Crystal structure of UBE2L3 bound to HOIP RING1 domain.
分子名称: E3 ubiquitin-protein ligase RNF31, Ubiquitin-conjugating enzyme E2 L3, ZINC ION
著者Liu, J, Wang, Y, Pan, L.
登録日2021-08-22
公開日2022-03-30
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献Mechanistic insights into the subversion of the linear ubiquitin chain assembly complex by the E3 ligase IpaH1.4 of Shigella flexneri.
Proc.Natl.Acad.Sci.USA, 119, 2022
7D6H
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BU of 7d6h by Molmil
Crystal structure of the SARS-CoV-2 papain-like protease (PLPro) C112S mutant
分子名称: PHOSPHATE ION, Papain-like protease, ZINC ION
著者Liu, J, Wang, Y, Pan, L.
登録日2020-09-30
公開日2020-11-04
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Development of potent and selective inhibitors targeting the papain-like protease of SARS-CoV-2.
Cell Chem Biol, 28, 2021
7E35
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BU of 7e35 by Molmil
Crystal structure of the SARS-CoV-2 papain-like protease (PLPro) C112S mutant bound to compound S43
分子名称: N-[(3-acetamidophenyl)methyl]-1-[(1R)-1-naphthalen-1-ylethyl]piperidine-4-carboxamide, Non-structural protein 3, ZINC ION
著者Liu, J, Wang, Y, Xu, X, Pan, L.
登録日2021-02-08
公開日2021-03-17
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Development of potent and selective inhibitors targeting the papain-like protease of SARS-CoV-2.
Cell Chem Biol, 28, 2021
7EAA
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BU of 7eaa by Molmil
crystal structure of NDP52 SKICH domain in complex with RB1CC1 coiled-coil domain
分子名称: Calcium-binding and coiled-coil domain-containing protein 2, RB1-inducible coiled-coil protein 1
著者Fu, T, Pan, L.
登録日2021-03-06
公開日2021-12-22
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural and biochemical advances on the recruitment of the autophagy-initiating ULK and TBK1 complexes by autophagy receptor NDP52.
Sci Adv, 7, 2021
7EA7
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BU of 7ea7 by Molmil
crystal structure of NAP1 LIR in complex with GABARAP
分子名称: Gamma-aminobutyric acid receptor-associated protein, NAP1_LIR motif
著者Fu, T, Pan, L.
登録日2021-03-06
公開日2021-12-22
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.69 Å)
主引用文献Structural and biochemical advances on the recruitment of the autophagy-initiating ULK and TBK1 complexes by autophagy receptor NDP52.
Sci Adv, 7, 2021
7EA2
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BU of 7ea2 by Molmil
crystal structure of NAP1 FIR in complex with RB1CC1 Claw domain
分子名称: 5-azacytidine-induced protein 2,RB1-inducible coiled-coil protein 1, CITRATE ANION, DI(HYDROXYETHYL)ETHER, ...
著者Fu, T, Pan, L.
登録日2021-03-06
公開日2021-12-22
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献Structural and biochemical advances on the recruitment of the autophagy-initiating ULK and TBK1 complexes by autophagy receptor NDP52.
Sci Adv, 7, 2021
8K7X
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BU of 8k7x by Molmil
Crystal structure of GH146 beta-L-arabinofuranosidase Bll3HypBA1 (amino acids 380-1223) in complex with Tris
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, MAGNESIUM ION, ...
著者Pan, L, Maruyama, S, Miyake, M, Fujita, K, Fushinobu, S.
登録日2023-07-27
公開日2024-02-21
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Bifidobacterial GH146 beta-L-arabinofuranosidase for the removal of beta 1,3-L-arabinofuranosides on plant glycans.
Appl.Microbiol.Biotechnol., 108, 2024
3Q8T
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BU of 3q8t by Molmil
Crystal structure of the coiled coil domain of Beclin 1, an essential autophagy protein
分子名称: Beclin-1
著者Li, X, Zhao, Y.
登録日2011-01-07
公開日2012-01-18
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Imperfect interface of Beclin1 coiled-coil domain regulates homodimer and heterodimer formation with Atg14L and UVRAG
Nat Commun, 3, 2012
3PVL
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BU of 3pvl by Molmil
Structure of myosin VIIa MyTH4-FERM-SH3 in complex with the CEN1 of Sans
分子名称: GLYCEROL, Myosin VIIa isoform 1, PHOSPHATE ION, ...
著者Wu, L, Pan, L.F, Wei, Z.Y, Zhang, M.J.
登録日2010-12-07
公開日2011-03-02
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of MyTH4-FERM domains in myosin VIIa tail bound to cargo.
Science, 331, 2011
6KBB
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BU of 6kbb by Molmil
Role of the DEF/Y motif of Swc5 in histone H2A.Z deposition
分子名称: Histone H2A type 1-D, Histone H2B type 2-E, SWR1-complex protein 5
著者Huang, Y, Zhou, Z.
登録日2019-06-24
公開日2020-01-29
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.365 Å)
主引用文献Role of a DEF/Y motif in histone H2A-H2B recognition and nucleosome editing.
Proc.Natl.Acad.Sci.USA, 117, 2020
7BV6
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BU of 7bv6 by Molmil
Crystal structure of the autophagic STX17/SNAP29/VAMP8 SNARE complex
分子名称: Synaptosomal-associated protein 29, Syntaxin-17, Vesicle-associated membrane protein 8
著者Li, Y, Pan, L.F.
登録日2020-04-09
公開日2020-09-02
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Decoding three distinct states of the Syntaxin17 SNARE motif in mediating autophagosome-lysosome fusion.
Proc.Natl.Acad.Sci.USA, 117, 2020

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件を2024-05-15に公開中

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