5X0W
Molecular mechanism for the binding between Sharpin and HOIP
Summary for 5X0W
Entry DOI | 10.2210/pdb5x0w/pdb |
Descriptor | E3 ubiquitin-protein ligase RNF31, Sharpin (2 entities in total) |
Functional Keywords | sharpin, hoip, linear ubiquitination, e3 enzyme, ligase-protein binding complex, ligase/protein binding |
Biological source | Homo sapiens (Human) More |
Cellular location | Cytoplasm : Q96EP0 Cytoplasm, cytosol : Q9H0F6 |
Total number of polymer chains | 8 |
Total formula weight | 120700.91 |
Authors | |
Primary citation | Liu, J.,Wang, Y.,Gong, Y.,Fu, T.,Hu, S.,Zhou, Z.,Pan, L. Structural Insights into SHARPIN-Mediated Activation of HOIP for the Linear Ubiquitin Chain Assembly Cell Rep, 21:27-36, 2017 Cited by PubMed: 28978479DOI: 10.1016/j.celrep.2017.09.031 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
Download full validation report