5X0W
Molecular mechanism for the binding between Sharpin and HOIP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, C, E, G) | E3 ubiquitin-protein ligase RNF31 | polymer | 166 | 18828.4 | 4 | UniProt (Q96EP0) Pfam (PF16678) | Homo sapiens (Human) | HOIL-1-interacting protein,HOIP,RING finger protein 31,Zinc in-between-RING-finger ubiquitin-associated domain protein |
| 2 | E, F, G, H (B, D, F, H) | Sharpin | polymer | 108 | 11346.8 | 4 | UniProt (Q9H0F6) | Homo sapiens (Human) | Shank-associated RH domain-interacting protein,Shank-interacting protein-like 1,hSIPL1 |
Sequence modifications
A, C, E, G: 480 - 639 (UniProt: Q96EP0)
B, D, F, H: 206 - 309 (UniProt: Q9H0F6)
| PDB | External Database | Details |
|---|---|---|
| Gly 474 | - | expression tag |
| Pro 475 | - | expression tag |
| Gly 476 | - | expression tag |
| Ser 477 | - | expression tag |
| Glu 478 | - | expression tag |
| Phe 479 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 202 | - | expression tag |
| Pro 203 | - | expression tag |
| Gly 204 | - | expression tag |
| Ser 205 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 120700.9 | |
| All* | Total formula weight | 120700.9 |
