7V8G

Crystal structure of HOIP RING1 domain bound to IpaH1.4 LRR domain

Summary for 7V8G

• Entry DOI: 10.2210/pdb7v8g/pdb
• Descriptor: RING-type E3 ubiquitin transferase, E3 ubiquitin-protein ligase RNF31, ZINC ION (3 entities in total)
• Functional Keywords: e3 ligase, ubiquitin, innate immune, ligase
• Biological source: Shigella flexneri serotype 5a (strain M90T); More
• Total number of polymer chains: 4
• Total formula weight: 77520.25

Authors

Liu, J.,Wang, Y.,Pan, L. (deposition date: 2021-08-23, release date: 2022-03-30, Last modification date: 2023-11-29)

• Primary citation: Liu, J.,Wang, Y.,Wang, D.,Wang, Y.,Xu, X.,Zhang, Y.,Li, Y.,Zhang, M.,Gong, X.,Tang, Y.,Shen, L.,Li, M.,Pan, L.; Mechanistic insights into the subversion of the linear ubiquitin chain assembly complex by the E3 ligase IpaH1.4 of Shigella flexneri.; Proc.Natl.Acad.Sci.USA, 119:e2116776119-e2116776119, 2022; PubMed: 35294289; DOI: 10.1073/pnas.2116776119

Experimental method

X-RAY DIFFRACTION (2.75 Å)