5T0H
| Structural basis for dynamic regulation of the human 26S proteasome | Descriptor: | 26S protease regulatory subunit 10B, 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, ... | Authors: | Chen, S, Wu, J, Lu, Y, Ma, Y.B, Lee, B.H, Yu, Z, Ouyang, Q, Finley, D, Kirschner, M.W, Mao, Y. | Deposit date: | 2016-08-16 | Release date: | 2016-10-19 | Last modified: | 2016-11-30 | Method: | ELECTRON MICROSCOPY (6.8 Å) | Cite: | Structural basis for dynamic regulation of the human 26S proteasome. Proc.Natl.Acad.Sci.USA, 113, 2016
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3M3B
| The roles of glutamates and metal ions in a rationally designed nitric oxide reductase based on myoglobin: Zn(II)-I107E FeBMb (Zn(II) binding to FeB site) | Descriptor: | Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ZINC ION | Authors: | Lin, Y.-W, Yeung, N, Gao, Y.-G, Miner, K.D, Tian, S, Robinson, H, Lu, Y. | Deposit date: | 2010-03-08 | Release date: | 2010-05-12 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Roles of glutamates and metal ions in a rationally designed nitric oxide reductase based on myoglobin. Proc.Natl.Acad.Sci.USA, 107, 2010
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3MN0
| Introducing a 2-His-1-Glu Non-Heme Iron Center into Myoglobin confers Nitric Oxide Reductase activity: Cu(II)-CN-FeBMb(-His) form | Descriptor: | COPPER (II) ION, CYANIDE ION, Myoglobin, ... | Authors: | Lin, Y.-W, Yeung, N, Gao, Y.-G, Miner, K.D, Lei, L, Robinson, H, Lu, Y. | Deposit date: | 2010-04-20 | Release date: | 2010-08-11 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Introducing a 2-his-1-glu nonheme iron center into myoglobin confers nitric oxide reductase activity. J.Am.Chem.Soc., 132, 2010
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3P65
| Time-dependent and Protein-directed In Situ Growth of Gold Nanoparticles in a Single Crystal of Lysozyme | Descriptor: | CHLORIDE ION, GOLD 3+ ION, GOLD ION, ... | Authors: | Wei, H, Wang, Z, Zhang, J, House, S, Gao, Y.-G, Yang, L, Robinson, H, Tan, L.H, Xing, H, Hou, C, Robertson, I.M, Zuo, J.-M, Lu, Y. | Deposit date: | 2010-10-11 | Release date: | 2011-02-09 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Time-dependent, protein-directed growth of gold nanoparticles within a single crystal of lysozyme. Nat Nanotechnol, 6, 2011
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3P68
| Time-dependent and Protein-directed In Situ Growth of Gold Nanoparticles in a Single Crystal of Lysozyme | Descriptor: | GOLD 3+ ION, Lysozyme C | Authors: | Wei, H, Wang, Z, Zhang, J, House, S, Gao, Y.-G, Yang, L, Robinson, H, Tan, L.H, Xing, H, Hou, C, Robertson, I.M, Zuo, J.-M, Lu, Y. | Deposit date: | 2010-10-11 | Release date: | 2011-02-09 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Time-dependent, protein-directed growth of gold nanoparticles within a single crystal of lysozyme. Nat Nanotechnol, 6, 2011
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2IA8
| Kinetic and Crystallographic Studies of a Redesigned Manganese-Binding Site in Cytochrome c Peroxidase | Descriptor: | Cytochrome c peroxidase, mitochondrial, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Pfister, T, Mirarefi, A.Y, Gengenbach, A.J, Zhao, X, Conaster, C.D.N, Gao, Y.G, Robinson, H, Zukoski, C.F, Wang, A.H.J, Lu, Y. | Deposit date: | 2006-09-07 | Release date: | 2007-08-28 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.48 Å) | Cite: | Kinetic and crystallographic studies of a redesigned manganese-binding site in cytochrome c peroxidase J.Biol.Inorg.Chem., 12, 2007
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3P66
| Time-dependent and Protein-directed In Situ Growth of Gold Nanoparticles in a Single Crystal of Lysozyme | Descriptor: | GOLD 3+ ION, Lysozyme C | Authors: | Wei, H, Wang, Z, Zhang, J, House, S, Gao, Y.-G, Yang, L, Robinson, H, Tan, L.H, Xing, H, Hou, C, Robertson, I.M, Zuo, J.-M, Lu, Y. | Deposit date: | 2010-10-11 | Release date: | 2011-02-09 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.36 Å) | Cite: | Time-dependent, protein-directed growth of gold nanoparticles within a single crystal of lysozyme. Nat Nanotechnol, 6, 2011
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3P4Z
| Time-dependent and Protein-directed In Situ Growth of Gold Nanoparticles in a Single Crystal of Lysozyme | Descriptor: | CHLORIDE ION, GOLD 3+ ION, GOLD ION, ... | Authors: | Wei, H, Wang, Z, Zhang, J, House, S, Gao, Y.-G, Yang, L, Robinson, H, Tan, L.H, Xing, H, Hou, C, Robertson, I.M, Zuo, J.-M, Lu, Y. | Deposit date: | 2010-10-07 | Release date: | 2011-02-09 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Time-dependent, protein-directed growth of gold nanoparticles within a single crystal of lysozyme. Nat Nanotechnol, 6, 2011
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3P64
| Time-dependent and Protein-directed In Situ Growth of Gold Nanoparticles in a Single Crystal of Lysozyme | Descriptor: | CHLORIDE ION, GOLD 3+ ION, GOLD ION, ... | Authors: | Wei, H, Wang, Z, Zhang, J, House, S, Gao, Y.-G, Yang, L, Robinson, H, Tan, L.H, Xing, H, Hou, C, Robertson, I.M, Zuo, J.-M, Lu, Y. | Deposit date: | 2010-10-11 | Release date: | 2011-02-09 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Time-dependent, protein-directed growth of gold nanoparticles within a single crystal of lysozyme. Nat Nanotechnol, 6, 2011
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2ICV
| Kinetic and Crystallographic Studies of a Redesigned Manganese-Binding Site in Cytochrome c Peroxidase | Descriptor: | COBALT (II) ION, Cytochrome c peroxidase, mitochondrial, ... | Authors: | Pfister, T, Mirarefi, A.Y, Gengenbach, A.J, Zhao, X, Conaster, C.D.N, Gao, Y.G, Robinson, H, Zukoski, C.F, Wang, A.H.J, Lu, Y. | Deposit date: | 2006-09-13 | Release date: | 2007-08-28 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Kinetic and crystallographic studies of a redesigned manganese-binding site in cytochrome c peroxidase J.Biol.Inorg.Chem., 12, 2007
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2JYW
| Solution structure of C-terminal domain of APOBEC3G | Descriptor: | DNA dC->dU-editing enzyme APOBEC-3G, ZINC ION | Authors: | Chen, K, Harjes, E, Gross, P.J, Fahmy, A, Lu, Y, Shindo, K, Harris, R.S, Matsuo, H. | Deposit date: | 2007-12-20 | Release date: | 2008-02-26 | Last modified: | 2021-10-20 | Method: | SOLUTION NMR | Cite: | Structure of the DNA deaminase domain of the HIV-1 restriction factor APOBEC3G. Nature, 452, 2008
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2KEM
| Extended structure of citidine deaminase domain of APOBEC3G | Descriptor: | DNA dC->dU-editing enzyme APOBEC-3G, ZINC ION | Authors: | Harjes, E, Gross, P.J, Chen, K, Lu, Y, Shindo, K, Nowarski, R, Gross, J.D, Kotler, M, Harris, R.S, Matsuo, H. | Deposit date: | 2009-01-30 | Release date: | 2009-06-02 | Last modified: | 2021-11-10 | Method: | SOLUTION NMR | Cite: | An extended structure of the APOBEC3G catalytic domain suggests a unique holoenzyme model J.Mol.Biol., 389, 2009
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7SII
| Human STING bound to both cGAMP and 1-[(2-chloro-6-fluorophenyl)methyl]-3,3-dimethyl-2-oxo-N-[(2,4,6-trifluorophenyl)methyl]-2,3-dihydro-1H-indole-6-carboxamide (Compound 53) | Descriptor: | 1-[(2-chloro-6-fluorophenyl)methyl]-3,3-dimethyl-2-oxo-N-[(2,4,6-trifluorophenyl)methyl]-2,3-dihydro-1H-indole-6-carboxamide, Stimulator of interferon genes protein, cGAMP | Authors: | Lu, D, Shang, G, Jie, L, Lu, Y, Bai, X.C, Zhang, X. | Deposit date: | 2021-10-14 | Release date: | 2022-02-02 | Last modified: | 2022-05-04 | Method: | ELECTRON MICROSCOPY (3.45 Å) | Cite: | Activation of STING by targeting a pocket in the transmembrane domain. Nature, 604, 2022
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5HAV
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4L0C
| Crystal structure of the N-Fopmylmaleamic acid deformylase Nfo(S94A) from Pseudomonas putida S16 | Descriptor: | ACETIC ACID, DI(HYDROXYETHYL)ETHER, Deformylase | Authors: | Chen, D, Lu, Y, Zhang, Z, Wu, G, Xu, P. | Deposit date: | 2013-05-31 | Release date: | 2014-06-04 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Crystal structure of the N-Fopmylmaleamic acid deformylase Nfo from Pseudomonas putida S16 To be Published
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4MFH
| Crystal Structure of M121G Azurin | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Azurin, COPPER (II) ION | Authors: | Tian, S, Lu, Y. | Deposit date: | 2013-08-27 | Release date: | 2014-01-15 | Last modified: | 2014-02-05 | Method: | X-RAY DIFFRACTION (1.54 Å) | Cite: | Copper-sulfenate complex from oxidation of a cavity mutant of Pseudomonas aeruginosa azurin. Proc.Natl.Acad.Sci.USA, 111, 2014
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4FWX
| Aquoferric F33Y CuB myoglobin (F33Y L29H F43H sperm whale myoglobin) | Descriptor: | Myoglobin, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Gao, Y.-G, Stoner-Ma, D, Robinson, H, Petrik, I.D, Miner, K.D, Lu, Y. | Deposit date: | 2012-07-02 | Release date: | 2012-07-18 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | A Designed Functional Metalloenzyme that Reduces O(2) to H(2) O with Over One Thousand Turnovers. Angew.Chem.Int.Ed.Engl., 51, 2012
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4FWZ
| Aquoferric CuB myoglobin (L29H F43H sperm whale myoglobin) | Descriptor: | Myoglobin, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Gao, Y.-G, Robinson, H, Petrik, I.D, Miner, K.D, Lu, Y. | Deposit date: | 2012-07-02 | Release date: | 2012-07-18 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | A Designed Functional Metalloenzyme that Reduces O(2) to H(2) O with Over One Thousand Turnovers. Angew.Chem.Int.Ed.Engl., 51, 2012
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4FWY
| F33Y CuB myoglobin (F33Y L29H F43H sperm whale myoglobin) with copper bound | Descriptor: | COPPER (II) ION, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Gao, Y.-G, Robinson, H, Petrik, I.D, Miner, K.D, Lu, Y. | Deposit date: | 2012-07-02 | Release date: | 2012-07-18 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | A Designed Functional Metalloenzyme that Reduces O(2) to H(2) O with Over One Thousand Turnovers. Angew.Chem.Int.Ed.Engl., 51, 2012
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7W59
| The cryo-EM structure of human pre-C*-I complex | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ... | Authors: | Zhan, X, Lu, Y, Shi, Y. | Deposit date: | 2021-11-29 | Release date: | 2022-06-22 | Last modified: | 2022-08-17 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Mechanism of exon ligation by human spliceosome. Mol.Cell, 82, 2022
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7W5A
| The cryo-EM structure of human pre-C*-II complex | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ... | Authors: | Zhan, X, Lu, Y, Shi, Y. | Deposit date: | 2021-11-29 | Release date: | 2022-06-22 | Last modified: | 2022-08-17 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Mechanism of exon ligation by human spliceosome. Mol.Cell, 82, 2022
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7W5B
| The cryo-EM structure of human C* complex | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ... | Authors: | Zhan, X, Lu, Y, Shi, Y. | Deposit date: | 2021-11-29 | Release date: | 2022-06-22 | Last modified: | 2022-08-17 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Mechanism of exon ligation by human spliceosome. Mol.Cell, 82, 2022
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5D6M
| Mn(II)-loaded MnCcP.1 | Descriptor: | Cytochrome c peroxidase, mitochondrial, MANGANESE (II) ION, ... | Authors: | Robinson, H, Gao, Y.-G, Hosseinzadeh, P, Lu, Y. | Deposit date: | 2015-08-12 | Release date: | 2016-03-09 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.653 Å) | Cite: | Enhancing Mn(II)-Binding and Manganese Peroxidase Activity in a Designed Cytochrome c Peroxidase through Fine-Tuning Secondary-Sphere Interactions. Biochemistry, 55, 2016
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5FC9
| Novel Purple Cupredoxin from Nitrosopumilus maritimus | Descriptor: | Blue (Type 1) copper domain protein, COPPER (II) ION | Authors: | Hosseinzadeh, P, Lu, Y, Robinson, H, Gao, Y.-G. | Deposit date: | 2015-12-15 | Release date: | 2016-05-11 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | A Purple Cupredoxin from Nitrosopumilus maritimus Containing a Mononuclear Type 1 Copper Center with an Open Binding Site. J.Am.Chem.Soc., 138, 2016
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7ENO
| Mutant strain M3 of foot-and-mouth disease virus type O | Descriptor: | VP1 of O type FMDV capsid, VP2 of O type FMDV capsid, VP3 of O type FMDV capsid, ... | Authors: | Dong, H, Lu, Y. | Deposit date: | 2021-04-18 | Release date: | 2021-06-02 | Last modified: | 2022-01-26 | Method: | ELECTRON MICROSCOPY (3.15 Å) | Cite: | A Heat-Induced Mutation on VP1 of Foot-and-Mouth Disease Virus Serotype O Enhanced Capsid Stability and Immunogenicity. J.Virol., 95, 2021
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