7XO2
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7Y9V
| Structure of the auxin exporter PIN1 in Arabidopsis thaliana in the IAA-bound state | Descriptor: | 1H-INDOL-3-YLACETIC ACID, Auxin efflux carrier component 1, nanobody | Authors: | Sun, L, Liu, X, Yang, Z, Xia, J. | Deposit date: | 2022-06-26 | Release date: | 2022-09-07 | Last modified: | 2022-09-28 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structural insights into auxin recognition and efflux by Arabidopsis PIN1. Nature, 609, 2022
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7Y9T
| Structure of the auxin exporter PIN1 in Arabidopsis thaliana in the apo state | Descriptor: | Auxin efflux carrier component 1, nanobody | Authors: | Sun, L, Liu, X, Yang, Z, Xia, J. | Deposit date: | 2022-06-26 | Release date: | 2022-09-07 | Last modified: | 2022-09-28 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural insights into auxin recognition and efflux by Arabidopsis PIN1. Nature, 609, 2022
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7Y9U
| Structure of the auxin exporter PIN1 in Arabidopsis thaliana in the NPA-bound state | Descriptor: | 2-(naphthalen-1-ylcarbamoyl)benzoic acid, Auxin efflux carrier component 1, nanobody | Authors: | Sun, L, Liu, X, Yang, Z, Xia, J. | Deposit date: | 2022-06-26 | Release date: | 2022-09-07 | Last modified: | 2022-09-28 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structural insights into auxin recognition and efflux by Arabidopsis PIN1. Nature, 609, 2022
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7C1D
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7CKI
| Crystal structure of Tryptophanyl-tRNA synthetase from Bacillus stearothermophilus in complex with chuangxinmycin and ATP | Descriptor: | (5~{S},6~{R})-5-methyl-7-thia-2-azatricyclo[6.3.1.0^{4,12}]dodeca-1(12),3,8,10-tetraene-6-carboxylic acid, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Lyu, G, Fan, S, Jin, Y, Liu, J, Zou, S, Wu, G, Yang, Z. | Deposit date: | 2020-07-17 | Release date: | 2021-07-21 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of Tryptophanyl-tRNA synthetase from Bacillus stearothermophilus in complex with chuangxinmycin and ATP To Be Published
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7DRK
| Crystal structure of phosphatidylglycerol phosphate synthase in complex with cytidine diphosphate-diacylglycerol | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 1,4-BUTANEDIOL, 5'-O-[(R)-{[(S)-{(2R)-2,3-bis[(9E)-octadec-9-enoyloxy]propoxy}(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]cytidine, ... | Authors: | Yang, B.W, Liu, Z.F. | Deposit date: | 2020-12-28 | Release date: | 2021-12-08 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | The phosphatidylglycerol phosphate synthase PgsA utilizes a trifurcated amphipathic cavity for catalysis at the membrane-cytosol interface. Curr Res Struct Biol, 3, 2021
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7DRJ
| Crystal structure of phosphatidylglycerol phosphate synthase in complex with phosphatidylglycerol phosphate | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 1,4-BUTANEDIOL, ACETIC ACID, ... | Authors: | Yang, B.W, Liu, Z.F. | Deposit date: | 2020-12-28 | Release date: | 2021-12-08 | Last modified: | 2022-02-16 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The phosphatidylglycerol phosphate synthase PgsA utilizes a trifurcated amphipathic cavity for catalysis at the membrane-cytosol interface. Curr Res Struct Biol, 3, 2021
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7EG4
| Cryo-EM structure of nauclefine-induced PDE3A-SLFN12 complex | Descriptor: | MAGNESIUM ION, Parvine, Schlafen family member 12, ... | Authors: | Liu, N, Chen, J, Wang, X.D, Wang, H.W. | Deposit date: | 2021-03-24 | Release date: | 2021-09-29 | Last modified: | 2022-05-25 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structure of PDE3A-SLFN12 complex and structure-based design for a potent apoptosis inducer of tumor cells. Nat Commun, 12, 2021
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7EG0
| Cryo-EM structure of anagrelide-induced PDE3A-SLFN12 complex | Descriptor: | 6,7-bis(chloranyl)-3,5-dihydro-1H-imidazo[2,1-b]quinazolin-2-one, MAGNESIUM ION, Schlafen family member 12, ... | Authors: | Liu, N, Chen, J, Wang, X.D, Wang, H.W. | Deposit date: | 2021-03-23 | Release date: | 2021-09-29 | Last modified: | 2022-05-25 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structure of PDE3A-SLFN12 complex and structure-based design for a potent apoptosis inducer of tumor cells. Nat Commun, 12, 2021
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7E0F
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7E1V
| Cryo-EM structure of apo hybrid respiratory supercomplex consisting of Mycobacterium tuberculosis complexIII and Mycobacterium smegmatis complexIV | Descriptor: | (2R)-2-(hexadecanoyloxy)-3-{[(S)-hydroxy{[(1R,2R,3R,4R,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propyl (9S)-9-methyloctadecanoate, (2R)-3-(((2-aminoethoxy)(hydroxy)phosphoryl)oxy)-2-(palmitoyloxy)propyl (E)-octadec-9-enoate, CARDIOLIPIN, ... | Authors: | Zhou, S, Wang, W, Gao, Y, Gong, H, Rao, Z. | Deposit date: | 2021-02-03 | Release date: | 2021-10-13 | Last modified: | 2022-07-27 | Method: | ELECTRON MICROSCOPY (2.68 Å) | Cite: | Structure of Mycobacterium tuberculosis cytochrome bcc in complex with Q203 and TB47, two anti-TB drug candidates. Elife, 10, 2021
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7E1W
| Cryo-EM structure of hybrid respiratory supercomplex consisting of Mycobacterium tuberculosis complexIII and Mycobacterium smegmatis complexIV in the presence of Q203 | Descriptor: | (2R)-2-(hexadecanoyloxy)-3-{[(S)-hydroxy{[(1R,2R,3R,4R,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propyl (9S)-9-methyloctadecanoate, (2R)-3-(((2-aminoethoxy)(hydroxy)phosphoryl)oxy)-2-(palmitoyloxy)propyl (E)-octadec-9-enoate, 6-chloranyl-2-ethyl-N-[[4-[4-[4-(trifluoromethyloxy)phenyl]piperidin-1-yl]phenyl]methyl]imidazo[1,2-a]pyridine-3-carboxamide, ... | Authors: | Zhou, S, Wang, W, Gao, Y, Gong, H, Rao, Z. | Deposit date: | 2021-02-03 | Release date: | 2021-10-27 | Last modified: | 2022-07-27 | Method: | ELECTRON MICROSCOPY (2.67 Å) | Cite: | Structure of Mycobacterium tuberculosis cytochrome bcc in complex with Q203 and TB47, two anti-TB drug candidates. Elife, 10, 2021
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7E1X
| Cryo-EM structure of hybrid respiratory supercomplex consisting of Mycobacterium tuberculosis complexIII and Mycobacterium smegmatis complexIV in presence of TB47 | Descriptor: | (2R)-2-(hexadecanoyloxy)-3-{[(S)-hydroxy{[(1R,2R,3R,4R,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propyl (9S)-9-methyloctadecanoate, (2R)-3-(((2-aminoethoxy)(hydroxy)phosphoryl)oxy)-2-(palmitoyloxy)propyl (E)-octadec-9-enoate, 5-methoxy-2-methyl-~{N}-[[4-[4-[4-(trifluoromethyloxy)phenyl]piperidin-1-yl]phenyl]methyl]pyrazolo[1,5-a]pyridine-3-carboxamide, ... | Authors: | Zhou, S, Wang, W, Gao, Y, Gong, H, Rao, Z. | Deposit date: | 2021-02-03 | Release date: | 2021-10-27 | Last modified: | 2022-07-27 | Method: | ELECTRON MICROSCOPY (2.93 Å) | Cite: | Structure of Mycobacterium tuberculosis cytochrome bcc in complex with Q203 and TB47, two anti-TB drug candidates. Elife, 10, 2021
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7EG1
| Cryo-EM structure of DNMDP-induced PDE3A-SLFN12 complex | Descriptor: | (4~{R})-3-[4-(diethylamino)-3-[oxidanyl(oxidanylidene)-$l^{4}-azanyl]phenyl]-4-methyl-4,5-dihydro-1~{H}-pyridazin-6-one, MAGNESIUM ION, Schlafen family member 12, ... | Authors: | Liu, N, Chen, J, Wang, X.D, Wang, H.W. | Deposit date: | 2021-03-23 | Release date: | 2021-11-03 | Last modified: | 2022-05-25 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structure of PDE3A-SLFN12 complex and structure-based design for a potent apoptosis inducer of tumor cells. Nat Commun, 12, 2021
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7EMY
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7EN1
| Pyochelin synthetase, a dimeric nonribosomal peptide synthetase elongation module-after-condensation | Descriptor: | (4S)-2-(2-hydroxyphenyl)-4,5-dihydro-1,3-thiazole-4-carboxylic acid, 2-HYDROXYBENZOIC ACID, 4'-PHOSPHOPANTETHEINE, ... | Authors: | Wang, J.L, Wang, Z.J. | Deposit date: | 2021-04-15 | Release date: | 2021-12-22 | Last modified: | 2023-07-05 | Method: | ELECTRON MICROSCOPY (3.47 Å) | Cite: | Catalytic trajectory of a dimeric nonribosomal peptide synthetase subunit with an inserted epimerase domain. Nat Commun, 13, 2022
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7EN2
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7FCF
| Crystal structure of T6SS Hcp protein | Descriptor: | Fimbrial protein | Authors: | Jobichen, C, Sivaraman, J. | Deposit date: | 2021-07-14 | Release date: | 2022-07-20 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Bacterial antagonism of Chromobacterium haemolyticum and characterization of its putative type VI secretion system. Res.Microbiol., 173, 2022
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7F0H
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6LB8
| Crystal structure of the Ca2+-free T4L-MICU1-MICU2 complex | Descriptor: | Calcium uptake protein 2, mitochondrial, Endolysin,Calcium uptake protein 1 | Authors: | Wu, W, Shen, Q, Zheng, J, Jia, Z. | Deposit date: | 2019-11-13 | Release date: | 2020-07-15 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.283 Å) | Cite: | The structure of the MICU1-MICU2 complex unveils the regulation of the mitochondrial calcium uniporter. Embo J., 39, 2020
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6LB7
| Crystal structure of the Ca2+-free and Ca2+-bound MICU1-MICU2 complex | Descriptor: | CALCIUM ION, Calcium uptake protein 1, mitochondrial, ... | Authors: | Wu, W, Shen, Q, Zheng, J, Jia, Z. | Deposit date: | 2019-11-13 | Release date: | 2020-07-15 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.101 Å) | Cite: | The structure of the MICU1-MICU2 complex unveils the regulation of the mitochondrial calcium uniporter. Embo J., 39, 2020
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6A73
| Complex structure of CSN2 with IP6 | Descriptor: | COP9 signalosome complex subunit 2,Endolysin, INOSITOL HEXAKISPHOSPHATE, SULFATE ION | Authors: | Liu, L, Li, D, Rao, F, Wang, T. | Deposit date: | 2018-07-02 | Release date: | 2019-07-03 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.447 Å) | Cite: | Basis for metabolite-dependent Cullin-RING ligase deneddylation by the COP9 signalosome. Proc.Natl.Acad.Sci.USA, 117, 2020
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