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7E0F

CryoEM structure of G51D alpha-synuclein amyloid fibril

Summary for 7E0F
Entry DOI10.2210/pdb7e0f/pdb
EMDB information30931
DescriptorAlpha-synuclein (1 entity in total)
Functional Keywordsamyloid fibril, protein fibril
Biological sourceHomo sapiens (Human)
Total number of polymer chains6
Total formula weight87204.88
Authors
Sun, Y.P.,Long, H.F.,Xia, W.C.,Liu, C. (deposition date: 2021-01-27, release date: 2021-10-06, Last modification date: 2022-02-23)
Primary citationSun, Y.,Long, H.,Xia, W.,Wang, K.,Zhang, X.,Sun, B.,Cao, Q.,Zhang, Y.,Dai, B.,Li, D.,Liu, C.
The hereditary mutation G51D unlocks a distinct fibril strain transmissible to wild-type alpha-synuclein.
Nat Commun, 12:6252-6252, 2021
Cited by
PubMed: 34716315
DOI: 10.1038/s41467-021-26433-2
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (3.02 Å)
Structure validation

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