7E0F
CryoEM structure of G51D alpha-synuclein amyloid fibril
Summary for 7E0F
Entry DOI | 10.2210/pdb7e0f/pdb |
EMDB information | 30931 |
Descriptor | Alpha-synuclein (1 entity in total) |
Functional Keywords | amyloid fibril, protein fibril |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 6 |
Total formula weight | 87204.88 |
Authors | Sun, Y.P.,Long, H.F.,Xia, W.C.,Liu, C. (deposition date: 2021-01-27, release date: 2021-10-06, Last modification date: 2022-02-23) |
Primary citation | Sun, Y.,Long, H.,Xia, W.,Wang, K.,Zhang, X.,Sun, B.,Cao, Q.,Zhang, Y.,Dai, B.,Li, D.,Liu, C. The hereditary mutation G51D unlocks a distinct fibril strain transmissible to wild-type alpha-synuclein. Nat Commun, 12:6252-6252, 2021 Cited by PubMed: 34716315DOI: 10.1038/s41467-021-26433-2 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.02 Å) |
Structure validation
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