6LB7

Crystal structure of the Ca2+-free and Ca2+-bound MICU1-MICU2 complex

Summary for 6LB7

• Entry DOI: 10.2210/pdb6lb7/pdb
• Descriptor: Calcium uptake protein 1, mitochondrial, Calcium uptake protein 2, mitochondrial, CALCIUM ION, ... (4 entities in total)
• Functional Keywords: calcium binding protein, mitochondrial, uniporter, ef-hand, metal binding protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 163686.54

Authors

Wu, W.,Shen, Q.,Zheng, J.,Jia, Z. (deposition date: 2019-11-13, release date: 2020-07-15, Last modification date: 2023-11-22)

• Primary citation: Wu, W.,Shen, Q.,Zhang, R.,Qiu, Z.,Wang, Y.,Zheng, J.,Jia, Z.; The structure of the MICU1-MICU2 complex unveils the regulation of the mitochondrial calcium uniporter.; Embo J., 39:e104285-e104285, 2020; PubMed: 32790952; DOI: 10.15252/embj.2019104285

Experimental method

X-RAY DIFFRACTION (2.101 Å)