7DRK

Crystal structure of phosphatidylglycerol phosphate synthase in complex with cytidine diphosphate-diacylglycerol

Summary for 7DRK

• Entry DOI: 10.2210/pdb7drk/pdb
• Related: 7DRJ
• Descriptor: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, ZINC ION, 5'-O-[(R)-{[(S)-{(2R)-2,3-bis[(9E)-octadec-9-enoyloxy]propoxy}(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]cytidine, ... (8 entities in total)
• Functional Keywords: substrate complex, phospholipid synthase, staphylococcus aureus, transferase., transferase
• Biological source: Staphylococcus aureus (strain N315)
• Total number of polymer chains: 2
• Total formula weight: 51624.19

Authors

Yang, B.W.,Liu, Z.F. (deposition date: 2020-12-28, release date: 2021-12-08, Last modification date: 2023-11-29)

• Primary citation: Yang, B.,Yao, H.,Li, D.,Liu, Z.; The phosphatidylglycerol phosphate synthase PgsA utilizes a trifurcated amphipathic cavity for catalysis at the membrane-cytosol interface.; Curr Res Struct Biol, 3:312-323, 2021; PubMed: 34901881; DOI: 10.1016/j.crstbi.2021.11.005

Experimental method

X-RAY DIFFRACTION (3 Å)