7DRK

Crystal structure of phosphatidylglycerol phosphate synthase in complex with cytidine diphosphate-diacylglycerol

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase	polymer	212	23199.5	2	UniProt (P63756) Pfam (PF01066) In PDB	Staphylococcus aureus (strain N315)	Phosphatidylglycerophosphate synthase,PGP synthase
2	A, B	ZINC ION	non-polymer		65.4	4	Chemie (ZN)
3	A, B	5'-O-[(R)-{[(S)-{(2R)-2,3-bis[(9E)-octadec-9-enoyloxy]propoxy}(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]cytidine	non-polymer		1006.1	2	Chemie (58A)
4	B, A	SN-GLYCEROL-3-PHOSPHATE	non-polymer		172.1	5	Chemie (G3P)
5	A, B	(2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate	non-polymer		356.5	3	Chemie (OLC)
6	B, A	1,4-BUTANEDIOL	non-polymer		90.1	10	Chemie (BU1)
7	A	ACETIC ACID	non-polymer		60.1	2	Chemie (ACY)
8		water	water		18.0	104	Chemie (HOH)

Sequence modifications

A, B: 1 - 192 (UniProt: P63756)

PDB	External Database	Details
Met -19	-	initiating methionine
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	46399.0
Non-Polymers*	Number of molecules	26
	Total formula weight	5225.2
All*	Total formula weight	51624.2

*Water molecules are not included.