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3M3Q
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BU of 3m3q by Molmil
Crystal Structure of Agrocybe aegerita lectin AAL complexed with Ganglosides GM1 pentasaccharide
分子名称: Anti-tumor lectin, beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-4)-[N-acetyl-alpha-neuraminic acid-(2-3)]beta-D-galactopyranose-(1-4)-beta-D-glucopyranose
著者Feng, L, Li, D, Wang, D.
登録日2010-03-09
公開日2010-12-01
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural insights into the recognition mechanism between an antitumor galectin AAL and the Thomsen-Friedenreich antigen
Faseb J., 24, 2010
3M3C
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BU of 3m3c by Molmil
Crystal Structure of Agrocybe aegerita lectin AAL complexed with p-Nitrophenyl TF disaccharide
分子名称: Anti-tumor lectin, P-NITROPHENOL, SULFATE ION, ...
著者Feng, L, Li, D, Wang, D.
登録日2010-03-09
公開日2010-12-01
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural insights into the recognition mechanism between an antitumor galectin AAL and the Thomsen-Friedenreich antigen
Faseb J., 24, 2010
3M3O
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BU of 3m3o by Molmil
Crystal Structure of Agrocybe aegerita lectin AAL mutant R85A complexed with p-Nitrophenyl TF disaccharide
分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Anti-tumor lectin, P-NITROPHENOL, ...
著者Feng, L, Li, D, Wang, D.
登録日2010-03-09
公開日2010-12-01
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural insights into the recognition mechanism between an antitumor galectin AAL and the Thomsen-Friedenreich antigen
Faseb J., 24, 2010
3M3E
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BU of 3m3e by Molmil
Crystal Structure of Agrocybe aegerita lectin AAL mutant E66A complexed with p-Nitrophenyl Thomsen-Friedenreich disaccharide
分子名称: Anti-tumor lectin, P-NITROPHENOL, beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-alpha-D-galactopyranose
著者Feng, L, Li, D, Wang, D.
登録日2010-03-09
公開日2010-12-01
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural insights into the recognition mechanism between an antitumor galectin AAL and the Thomsen-Friedenreich antigen
Faseb J., 24, 2010
3U28
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BU of 3u28 by Molmil
Crystal structure of a Cbf5-Nop10-Gar1 complex from Saccharomyces cerevisiae
分子名称: H/ACA ribonucleoprotein complex subunit 1, H/ACA ribonucleoprotein complex subunit 3, H/ACA ribonucleoprotein complex subunit 4
著者Ye, K, Li, S.
登録日2011-10-02
公開日2011-12-14
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Reconstitution and structural analysis of the yeast box H/ACA RNA-guided pseudouridine synthase
Genes Dev., 25, 2011
6L1T
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BU of 6l1t by Molmil
Cryo-EM structure of phosphorylated Tyr39 a-synuclein amyloid fibril
分子名称: Alpha-synuclein
著者Liu, C, Li, Y.M, Zhao, K, Lim, Y.J, Liu, Z.Y.
登録日2019-09-30
公開日2020-08-12
最終更新日2020-09-02
実験手法ELECTRON MICROSCOPY (3.22 Å)
主引用文献Parkinson's disease-related phosphorylation at Tyr39 rearranges alpha-synuclein amyloid fibril structure revealed by cryo-EM.
Proc.Natl.Acad.Sci.USA, 117, 2020
6L1U
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BU of 6l1u by Molmil
Cryo-EM structure of phosphorylated Tyr39 alpha-synuclein amyloid fibril
分子名称: Alpha-synuclein
著者Liu, C, Li, Y.M, Zhao, K, Lim, Y.J, Liu, Z.Y.
登録日2019-09-30
公開日2020-08-12
最終更新日2020-09-02
実験手法ELECTRON MICROSCOPY (3.37 Å)
主引用文献Parkinson's disease-related phosphorylation at Tyr39 rearranges alpha-synuclein amyloid fibril structure revealed by cryo-EM.
Proc.Natl.Acad.Sci.USA, 117, 2020
7OTJ
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BU of 7otj by Molmil
Crystal structure of Pif1 helicase from Candida albicans
分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent DNA helicase PIF1, DNA (5'-D(P*TP*TP*TP*TP*TP*T)-3'), ...
著者Rety, S, Xi, X.G.
登録日2021-06-10
公開日2021-07-07
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.58 Å)
主引用文献Structural study of the function of Candida Albicans Pif1.
Biochem.Biophys.Res.Commun., 567, 2021
3IKA
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BU of 3ika by Molmil
Crystal Structure of EGFR 696-1022 T790M Mutant Covalently Binding to WZ4002
分子名称: Epidermal growth factor receptor, N-{3-[(5-chloro-2-{[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)oxy]phenyl}prop-2-enamide
著者Yun, C.-H, Eck, M.J.
登録日2009-08-05
公開日2010-01-12
最終更新日2021-10-13
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Novel mutant-selective EGFR kinase inhibitors against EGFR T790M.
Nature, 462, 2009
7V1N
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BU of 7v1n by Molmil
Structure of the Clade 2 C. difficile TcdB in complex with its receptor TFPI
分子名称: Isoform Beta of Tissue factor pathway inhibitor, Toxin B
著者Luo, J, Yang, Q, Zhang, X, Zhang, Y, Wan, L, Li, Y, Tao, L.
登録日2021-08-05
公開日2022-02-23
最終更新日2022-03-30
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献TFPI is a colonic crypt receptor for TcdB from hypervirulent clade 2 C. difficile.
Cell, 185, 2022
3A9U
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BU of 3a9u by Molmil
Crystal structures and enzymatic mechanisms of a Populus tomentosa 4-coumarate--CoA ligase
分子名称: 4-coumarate--CoA ligase
著者Hu, Y.
登録日2009-11-06
公開日2010-09-08
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structures of a Populus tomentosa 4-coumarate:CoA ligase shed light on its enzymatic mechanisms
Plant Cell, 22, 2010
3A9V
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BU of 3a9v by Molmil
Crystal structures and enzymatic mechanisms of a Populus tomentosa 4-coumarate--CoA ligase
分子名称: 4-coumarate--CoA ligase, ADENOSINE MONOPHOSPHATE
著者Hu, Y.
登録日2009-11-06
公開日2010-09-08
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structures of a Populus tomentosa 4-coumarate:CoA ligase shed light on its enzymatic mechanisms
Plant Cell, 22, 2010
5WTT
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BU of 5wtt by Molmil
Structure of the 093G9 Fab in complex with the epitope peptide
分子名称: Epitope peptide of Cyr61, Heavy chain of 093G9 Fab, Light chain of 093G9 Fab
著者Zhong, C, Hu, K, Shen, J, Ding, J.
登録日2016-12-14
公開日2017-12-20
最終更新日2019-01-02
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Molecular basis for the recognition of CCN1 by monoclonal antibody 093G9.
J. Mol. Recognit., 30, 2017
6V7D
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BU of 6v7d by Molmil
Human Arginase1 Complexed with Bicyclic Inhibitor Compound 10
分子名称: Arginase-1, MANGANESE (II) ION, {3-[(3aR,4R,5S,6aR)-4-azaniumyl-4-carboxyoctahydrocyclopenta[b]pyrrol-1-ium-5-yl]propyl}(trihydroxy)borate(1-)
著者Palte, R.L, Lesburg, C.A.
登録日2019-12-08
公開日2020-05-06
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Discovery and Optimization of Rationally Designed Bicyclic Inhibitors of Human Arginase to Enhance Cancer Immunotherapy.
Acs Med.Chem.Lett., 11, 2020
6C59
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BU of 6c59 by Molmil
Chimeric Pol kappa RIR Rev1 C-terminal domain
分子名称: ACETATE ION, Chimeric Pol kappa RIR Rev1 C-terminal domain
著者Wojtaszek, J.L, Zhou, P.
登録日2018-01-15
公開日2019-06-12
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献A Small Molecule Targeting Mutagenic Translesion Synthesis Improves Chemotherapy.
Cell, 178, 2019
6V7E
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BU of 6v7e by Molmil
Human Arginase1 Complexed with Bicyclic Inhibitor Compound 12
分子名称: 3-[(5~{S},7~{S},8~{S})-8-azanyl-8-carboxy-1-azaspiro[4.4]nonan-7-yl]propyl-$l^{3}-oxidanyl-bis(oxidanyl)boranuide, Arginase-1, MANGANESE (II) ION
著者Palte, R.L.
登録日2019-12-08
公開日2020-05-06
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Discovery and Optimization of Rationally Designed Bicyclic Inhibitors of Human Arginase to Enhance Cancer Immunotherapy.
Acs Med.Chem.Lett., 11, 2020
6C8C
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BU of 6c8c by Molmil
Chimeric Pol kappa RIR Rev1 C-terminal domain in complex with JHRE06
分子名称: 8-chloro-2-[(2,4-dichlorophenyl)amino]-3-(3-methylbutanoyl)-5-nitroquinolin-4(1H)-one, Chimeric protein of the Pol Kappa RIR helix and the Rev1 C-terminal domain
著者Najeeb, J, Zhou, P.
登録日2018-01-24
公開日2019-06-12
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献A Small Molecule Targeting Mutagenic Translesion Synthesis Improves Chemotherapy.
Cell, 178, 2019
6VIL
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BU of 6vil by Molmil
Crystal structure of mouse BAHCC1 BAH domain in complex with H3K27me3
分子名称: BAH and coiled-coil domain-containing protein 1, Histone H3.1
著者Song, J, Lu, J.
登録日2020-01-13
公開日2020-09-16
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.301 Å)
主引用文献BAHCC1 binds H3K27me3 via a conserved BAH module to mediate gene silencing and oncogenesis.
Nat.Genet., 52, 2020
6X2A
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BU of 6x2a by Molmil
SARS-CoV-2 u1S2q 1-RBD Up Spike Protein Trimer
分子名称: Spike glycoprotein
著者Henderson, R, Acharya, P.
登録日2020-05-20
公開日2020-05-27
最終更新日2021-08-04
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Controlling the SARS-CoV-2 spike glycoprotein conformation.
Nat.Struct.Mol.Biol., 27, 2020
6X29
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BU of 6x29 by Molmil
SARS-CoV-2 rS2d Down State Spike Protein Trimer
分子名称: Spike glycoprotein
著者Henderson, R, Acharya, P.
登録日2020-05-20
公開日2020-05-27
最終更新日2020-10-21
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Controlling the SARS-CoV-2 spike glycoprotein conformation.
Nat.Struct.Mol.Biol., 27, 2020
6LNQ
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BU of 6lnq by Molmil
The co-crystal structure of SARS-CoV 3C Like Protease with aldehyde inhibitor M7
分子名称: N-[(2S)-3-methyl-1-[[(2S)-4-methyl-1-oxidanylidene-1-[[(2S)-1-oxidanylidene-3-[(3S)-2-oxidanylidenepyrrolidin-3-yl]propan-2-yl]amino]pentan-2-yl]amino]-1-oxidanylidene-butan-2-yl]-1H-indole-2-carboxamide, Severe Acute Respiratory Syndrome Coronavirus 3c Like Protease
著者Wang, H, Shang, L.Q.
登録日2020-01-01
公開日2020-05-27
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.244 Å)
主引用文献Comprehensive Insights into the Catalytic Mechanism of Middle East Respiratory Syndrome 3C-Like Protease and Severe Acute Respiratory Syndrome 3C-Like Protease.
Acs Catalysis, 10, 2020
6LO0
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BU of 6lo0 by Molmil
The co-crystal structure of Severe Acute Respiratory Syndrome Coronavirus 3C Like Protease with aldehyde M14
分子名称: (2~{S})-4-methyl-~{N}-[(2~{S})-1-oxidanylidene-3-[(3~{S})-2-oxidanylidenepyrrolidin-3-yl]propan-2-yl]-2-[[(~{E})-3-phenylprop-2-enoyl]amino]pentanamide, Replicase polyprotein 1a
著者Wang, H, Shang, L.Q.
登録日2020-01-02
公開日2020-05-27
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.939 Å)
主引用文献Comprehensive Insights into the Catalytic Mechanism of Middle East Respiratory Syndrome 3C-Like Protease and Severe Acute Respiratory Syndrome 3C-Like Protease.
Acs Catalysis, 10, 2020
6X2C
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BU of 6x2c by Molmil
SARS-CoV-2 u1S2q All Down RBD State Spike Protein Trimer
分子名称: Spike glycoprotein
著者Henderson, R, Acharya, P.
登録日2020-05-20
公開日2020-05-27
最終更新日2021-07-07
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Controlling the SARS-CoV-2 spike glycoprotein conformation.
Nat.Struct.Mol.Biol., 27, 2020
4PGO
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BU of 4pgo by Molmil
Crystal structure of hypothetical protein PF0907 from Pyrococcus furiosus solved by sulfur SAD using Swiss Light Source data
分子名称: CHLORIDE ION, Uncharacterized protein
著者Weinert, T, Waltersperger, S, Olieric, V, Panepucci, E, Chen, L, Rose, J.P, Wang, M, Wang, B.C, Southeast Collaboratory for Structural Genomics (SECSG)
登録日2014-05-02
公開日2014-12-10
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Fast native-SAD phasing for routine macromolecular structure determination.
Nat.Methods, 12, 2015
6X2B
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BU of 6x2b by Molmil
SARS-CoV-2 u1S2q 2-RBD Up Spike Protein Trimer
分子名称: Spike glycoprotein
著者Henderson, R, Acharya, P.
登録日2020-05-20
公開日2020-05-27
最終更新日2021-08-04
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Controlling the SARS-CoV-2 spike glycoprotein conformation.
Nat.Struct.Mol.Biol., 27, 2020

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