6L1T

Cryo-EM structure of phosphorylated Tyr39 a-synuclein amyloid fibril

Summary for 6L1T

• Entry DOI: 10.2210/pdb6l1t/pdb
• EMDB information: 0801
• Descriptor: Alpha-synuclein (1 entity in total)
• Functional Keywords: amyloid fibril, protein fibril
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 10
• Total formula weight: 145560.87

Authors

Liu, C.,Li, Y.M.,Zhao, K.,Lim, Y.J.,Liu, Z.Y. (deposition date: 2019-09-30, release date: 2020-08-12, Last modification date: 2020-09-02)

• Primary citation: Zhao, K.,Lim, Y.J.,Liu, Z.,Long, H.,Sun, Y.,Hu, J.J.,Zhao, C.,Tao, Y.,Zhang, X.,Li, D.,Li, Y.M.,Liu, C.; Parkinson's disease-related phosphorylation at Tyr39 rearranges alpha-synuclein amyloid fibril structure revealed by cryo-EM.; Proc.Natl.Acad.Sci.USA, 117:20305-20315, 2020; PubMed: 32737160; DOI: 10.1073/pnas.1922741117

Experimental method

ELECTRON MICROSCOPY (3.22 Å)