6LNQ
The co-crystal structure of SARS-CoV 3C Like Protease with aldehyde inhibitor M7
Summary for 6LNQ
Entry DOI | 10.2210/pdb6lnq/pdb |
Descriptor | Severe Acute Respiratory Syndrome Coronavirus 3c Like Protease, N-[(2S)-3-methyl-1-[[(2S)-4-methyl-1-oxidanylidene-1-[[(2S)-1-oxidanylidene-3-[(3S)-2-oxidanylidenepyrrolidin-3-yl]propan-2-yl]amino]pentan-2-yl]amino]-1-oxidanylidene-butan-2-yl]-1H-indole-2-carboxamide (3 entities in total) |
Functional Keywords | coronavirus 3c, protease, viral protein-inhibitor complex, viral protein/inhibitor |
Biological source | Severe acute respiratory syndrome-related coronavirus (SARSr-CoV) |
Total number of polymer chains | 1 |
Total formula weight | 34388.25 |
Authors | Wang, H.,Shang, L.Q. (deposition date: 2020-01-01, release date: 2020-05-27, Last modification date: 2023-11-22) |
Primary citation | Wang, H.,He, S.,Deng, W.,Zhang, Y.,Li, G.,Sun, J.,Zhao, W.,Guo, Y.,Yin, Z.,Li, D.,Shang, L. Comprehensive Insights into the Catalytic Mechanism of Middle East Respiratory Syndrome 3C-Like Protease and Severe Acute Respiratory Syndrome 3C-Like Protease. Acs Catalysis, 10:5871-5890, 2020 Cited by PubMed: 32391184DOI: 10.1021/acscatal.0c00110 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.244 Å) |
Structure validation
Download full validation report