3M3E

Crystal Structure of Agrocybe aegerita lectin AAL mutant E66A complexed with p-Nitrophenyl Thomsen-Friedenreich disaccharide

Summary for 3M3E

• Entry DOI: 10.2210/pdb3m3e/pdb
• Related: 3AFK 3M3C 3M3O 3M3Q
• Related PRD ID: PRD_900084
• Descriptor: Anti-tumor lectin, beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-alpha-D-galactopyranose, P-NITROPHENOL, ... (4 entities in total)
• Functional Keywords: galectin, aal, mutant, thomsen-friedenreich disaccharide, apoptosis, hydrolase, lectin, nuclease, gal-beta-1, 3-galnac-alpha-o-p-nitrophenyl
• Biological source: Agrocybe aegerita (Black poplar mushroom)
• Total number of polymer chains: 4
• Total formula weight: 71262.77

Authors

Feng, L.,Li, D.,Wang, D. (deposition date: 2010-03-09, release date: 2010-12-01, Last modification date: 2023-11-01)

• Primary citation: Feng, L.,Sun, H.,Zhang, Y.,Li, D.F.,Wang, D.C.; Structural insights into the recognition mechanism between an antitumor galectin AAL and the Thomsen-Friedenreich antigen; Faseb J., 24:3861-3868, 2010; PubMed: 20530247; DOI: 10.1096/fj.10-159111

Experimental method

X-RAY DIFFRACTION (2.1 Å)