3M3E
Crystal Structure of Agrocybe aegerita lectin AAL mutant E66A complexed with p-Nitrophenyl Thomsen-Friedenreich disaccharide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Anti-tumor lectin | polymer | 161 | 17293.2 | 4 | UniProt (Q6WY08) Pfam (PF00337) | Agrocybe aegerita (Black poplar mushroom) | AAL |
| 2 | E, F, G, H (E, F, G, H) | beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-alpha-D-galactopyranose | branched | 383.3 | 4 | In PDB BIRD (PRD_900084) GlyTouCan (G00031MO) | Thomsen-Friedenreich antigen | ||
| 3 | I, J, K, L (A, B, C, D) | P-NITROPHENOL | non-polymer | 139.1 | 4 | Chemie (NPO) | |||
| 4 | M, N, O, P (A, B, C, D) | water | water | 18.0 | 582 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 158 (UniProt: Q6WY08)
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | expression tag |
| Ala 66 | Glu 66 | engineered mutation |
| Ser 132 | Leu 132 | SEE REMARK 999 |
| Leu 159 | - | expression tag |
| Glu 160 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 69172.9 | |
| Branched | Number of molecules | 4 |
| Total formula weight | 1533.4 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 556.4 | |
| All* | Total formula weight | 71262.8 |
