5Y5T
 
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3QHP
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5GHV
 | | Crystal structure of an inhibitor-bound Syk | | 分子名称: | 1-({1-[2-({3,5-dimethyl-4-[2-(pyrrolidin-1-yl)ethoxy]phenyl}amino)pyrimidin-4-yl]-4-methyl-1H-pyrrol-3-yl}methyl)azetidin-3-ol, Tyrosine-protein kinase SYK | | 著者 | Lee, S.J, Choi, J, Han, B.G, Song, H, Koh, J.S, Lee, B.I. | | 登録日 | 2016-06-20 | | 公開日 | 2016-07-06 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal structures of spleen tyrosine kinase in complex with novel inhibitors: structural insights for design of anticancer drugs
Febs J., 283, 2016
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1GCJ
 | | N-TERMINAL FRAGMENT OF IMPORTIN-BETA | | 分子名称: | IMPORTIN BETA | | 著者 | Lee, S.J, Imamoto, N, Sakai, H, Nakagawa, A, Kose, S, Koike, M, Yamamoto, M, Kumasaka, T, Yoneda, Y, Tsukihara, T. | | 登録日 | 2000-07-31 | | 公開日 | 2000-10-18 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | The adoption of a twisted structure of importin-beta is essential for the protein-protein interaction required for nuclear transport.
J.Mol.Biol., 302, 2000
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3MYP
 | | Crystal structure of tagatose-1,6-bisphosphate aldolase from Staphylococcus aureus | | 分子名称: | Tagatose 1,6-diphosphate aldolase | | 著者 | Lee, S.J, Kim, H.S, Kim, D.J, Yoon, H.J, Kim, K.H, Yoon, J.Y, Suh, S.W. | | 登録日 | 2010-05-10 | | 公開日 | 2011-01-26 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.99 Å) | | 主引用文献 | Crystal structures of LacD from Staphylococcus aureus and LacD.1 from Streptococcus pyogenes: Insights into substrate specificity and virulence gene regulation
Febs Lett., 585, 2011
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3MYO
 | | Crystal structure of tagatose-1,6-bisphosphate aldolase from Streptococcus pyogenes | | 分子名称: | Tagatose 1,6-diphosphate aldolase 1 | | 著者 | Lee, S.J, Kim, H.S, Kim, D.J, Yoon, H.J, Kim, K.H, Yoon, J.Y, Suh, S.W. | | 登録日 | 2010-05-10 | | 公開日 | 2011-01-26 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structures of LacD from Staphylococcus aureus and LacD.1 from Streptococcus pyogenes: Insights into substrate specificity and virulence gene regulation
Febs Lett., 585, 2011
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2BKU
 | | Kap95p:RanGTP complex | | 分子名称: | GTP-BINDING NUCLEAR PROTEIN RAN, GUANOSINE-5'-TRIPHOSPHATE, IMPORTIN BETA-1 SUBUNIT, ... | | 著者 | Lee, S.J, Matsuura, Y, Liu, S.M, Stewart, M. | | 登録日 | 2005-02-21 | | 公開日 | 2005-05-04 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural Basis for Nuclear Import Complex Dissociation by Rangtp
Nature, 435, 2005
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1UKL
 | | Crystal structure of Importin-beta and SREBP-2 complex | | 分子名称: | Importin beta-1 subunit, Sterol regulatory element binding protein-2 | | 著者 | Lee, S.J, Sekimoto, T, Yamashita, E, Nagoshi, E, Nakagawa, A, Imamoto, N, Yoshimura, M, Sakai, H, Tsukihara, T, Yoneda, Y. | | 登録日 | 2003-08-26 | | 公開日 | 2003-12-09 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | The Structure of Importin-beta Bound to SREBP-2: Nuclear Import of a Transcription Factor
Science, 302, 2003
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1WDW
 | | Structural basis of mutual activation of the tryptophan synthase a2b2 complex from a hyperthermophile, Pyrococcus furiosus | | 分子名称: | PYRIDOXAL-5'-PHOSPHATE, Tryptophan synthase alpha chain, Tryptophan synthase beta chain 1 | | 著者 | Lee, S.J, Ogasahara, K, Ma, J, Nishio, K, Ishida, M, Yamagata, Y, Tsukihara, T, Yutani, K, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2004-05-19 | | 公開日 | 2005-07-12 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Conformational Changes in the Tryptophan Synthase from a Hyperthermophile upon alpha(2)beta(2) Complex Formation: Crystal Structure of the Complex
Biochemistry, 44, 2005
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3WWS
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4QXZ
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1IZZ
 | | Crystal structure of Hsp31 | | 分子名称: | Hsp31 | | 著者 | Cha, S.S, Lee, S.J. | | 登録日 | 2002-10-16 | | 公開日 | 2003-10-16 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | | 主引用文献 | Crystal structures of human DJ-1 and Escherichia coli Hsp31, which share an evolutionarily conserved domain
J.Biol.Chem., 278, 2003
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1IZY
 | | Crystal structure of Hsp31 | | 分子名称: | Hsp31 | | 著者 | Cha, S.S, Lee, S.J. | | 登録日 | 2002-10-16 | | 公開日 | 2003-10-16 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal structures of human DJ-1 and Escherichia coli Hsp31, which share an evolutionarily conserved domain
J.Biol.Chem., 278, 2003
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6JKG
 | | The NAD+-free form of human NSDHL | | 分子名称: | Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating | | 著者 | Kim, D, Lee, S.J, Lee, B. | | 登録日 | 2019-02-28 | | 公開日 | 2020-03-04 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Crystal structures of human NSDHL and development of its novel inhibitor with the potential to suppress EGFR activity.
Cell.Mol.Life Sci., 78, 2021
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6JKH
 | | The NAD+-bound form of human NSDHL | | 分子名称: | NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating | | 著者 | Kim, D, Lee, S.J, Lee, B. | | 登録日 | 2019-02-28 | | 公開日 | 2020-03-04 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Crystal structures of human NSDHL and development of its novel inhibitor with the potential to suppress EGFR activity.
Cell.Mol.Life Sci., 78, 2021
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4XGQ
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4XGR
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7CJ2
 | | Crystal structure of the Fab antibody complexed with human YKL-40 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Chitinase 3-like 1 (Cartilage glycoprotein-39), isoform CRA_a, ... | | 著者 | Choi, S, Na, J.H, Lee, S.J, Woo, J.R, Kim, D.Y, Hong, J.T, Lee, W.K. | | 登録日 | 2020-07-09 | | 公開日 | 2021-07-14 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal structure of the Fab antibody complexed with human YKL-40
To Be Published
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5XE2
 | | Endoribonuclease from Mycobacterial species | | 分子名称: | Endoribonuclease MazF4 | | 著者 | Ahn, D.-H, Lee, K.-Y, Lee, S.J, Yoon, H.J, Kim, S.-J, Lee, B.-J. | | 登録日 | 2017-03-31 | | 公開日 | 2017-10-11 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | | 主引用文献 | Structural analyses of the MazEF4 toxin-antitoxin pair in Mycobacterium tuberculosis provide evidence for a unique extracellular death factor.
J. Biol. Chem., 292, 2017
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5XE3
 | | Endoribonuclease in complex with its cognate antitoxin from Mycobacterial species | | 分子名称: | Endoribonuclease MazF4, Probable antitoxin MazE4 | | 著者 | Ahn, D.-H, Lee, K.-Y, Lee, S.J, Yoon, H.J, Kim, S.-J, Lee, B.-J. | | 登録日 | 2017-03-31 | | 公開日 | 2017-10-11 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural analyses of the MazEF4 toxin-antitoxin pair in Mycobacterium tuberculosis provide evidence for a unique extracellular death factor.
J. Biol. Chem., 292, 2017
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8I7Q
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7BYO
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7BYP
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3V6A
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6JHW
 | | Structure of anti-CRISPR AcrIIC3 and NmeCas9 HNH | | 分子名称: | AcrIIC3, CRISPR-associated endonuclease Cas9 | | 著者 | Suh, J.Y, Lee, B.J, Lee, S.J, Kim, Y. | | 登録日 | 2019-02-19 | | 公開日 | 2019-08-28 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | | 主引用文献 | Anti-CRISPR AcrIIC3 discriminates between Cas9 orthologs via targeting the variable surface of the HNH nuclease domain.
Febs J., 286, 2019
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