5XE3

Endoribonuclease in complex with its cognate antitoxin from Mycobacterial species

Summary for 5XE3

• Entry DOI: 10.2210/pdb5xe3/pdb
• Related: 5XE2
• Descriptor: Endoribonuclease MazF4, Probable antitoxin MazE4 (3 entities in total)
• Functional Keywords: endonuclease, hydrolase-antitoxin complex, hydrolase/antitoxin
• Biological source: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv); More
• Total number of polymer chains: 6
• Total formula weight: 65211.37

Authors

Ahn, D.-H.,Lee, K.-Y.,Lee, S.J.,Yoon, H.J.,Kim, S.-J.,Lee, B.-J. (deposition date: 2017-03-31, release date: 2017-10-11, Last modification date: 2023-11-22)

• Primary citation: Ahn, D.H.,Lee, K.Y.,Lee, S.J.,Park, S.J.,Yoon, H.J.,Kim, S.J.,Lee, B.J.; Structural analyses of the MazEF4 toxin-antitoxin pair in Mycobacterium tuberculosis provide evidence for a unique extracellular death factor.; J. Biol. Chem., 292:18832-18847, 2017; PubMed: 28972145; DOI: 10.1074/jbc.M117.807974

Experimental method

X-RAY DIFFRACTION (2.3 Å)