6X3M
| Crystal structure of full-length Streptococcal bacteriophage hyaluronidase in complex with unsaturated hyaluronan octa-saccharides | Descriptor: | 4-deoxy-alpha-L-threo-hex-4-enopyranuronic acid-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-deoxy-alpha-L-threo-hex-4-enopyranuronic acid-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hyaluronoglucosaminidase | Authors: | Deivanayagam, C, Schormann, N. | Deposit date: | 2020-05-21 | Release date: | 2021-06-09 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.581 Å) | Cite: | Crystal Structure of Streptococcal Bacteriophage Hyaluronidase:
Presence of a Prokaryotic Collagen and Elucidation of Catalytic Mechanism To Be Published
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7YLK
| Myoglobin containing Ir complex | Descriptor: | Myoglobin, SULFATE ION, delta-{1-([2,2'-bipyridin]-5-ylmethyl)pyrrolidine-2,5-dione}bis[2-(2,4-difluorophenyl)pyridine)]iridium(III), ... | Authors: | Lee, J.H, Song, W.J. | Deposit date: | 2022-07-26 | Release date: | 2023-03-15 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.63 Å) | Cite: | Photocatalytic C-O Coupling Enzymes That Operate via Intramolecular Electron Transfer. J.Am.Chem.Soc., 145, 2023
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5H22
| Hsp90 alpha N-terminal domain in complex with an inhibitor | Descriptor: | 4-chloranyl-7-[(4-methoxy-3,5-dimethyl-pyridin-2-yl)methyl]-5-(phenylmethyl)pyrrolo[2,3-d]pyrimidin-2-amine, Hsp90aa1 protein | Authors: | Kim, E.E, Shin, S.C, Keum, G.C. | Deposit date: | 2016-10-13 | Release date: | 2017-10-11 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.499 Å) | Cite: | Synthesis and in vitro antiproliferative activity of C5-benzyl substituted 2-amino-pyrrolo[2,3-d]pyrimidines as potent Hsp90 inhibitors. Bioorg. Med. Chem. Lett., 27, 2017
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3OU2
| DhpI-SAH complex structure | Descriptor: | S-ADENOSYL-L-HOMOCYSTEINE, SAM-dependent methyltransferase | Authors: | Bae, B, Nair, S.K. | Deposit date: | 2010-09-14 | Release date: | 2010-10-27 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Characterization and structure of DhpI, a phosphonate O-methyltransferase involved in dehydrophos biosynthesis. Proc.Natl.Acad.Sci.USA, 107, 2010
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3OU7
| DhpI-SAM-HEP complex | Descriptor: | (2-hydroxyethyl)phosphonic acid, S-ADENOSYLMETHIONINE, SAM-dependent methyltransferase, ... | Authors: | Bae, B, Nair, S.K. | Deposit date: | 2010-09-14 | Release date: | 2010-10-27 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Characterization and structure of DhpI, a phosphonate O-methyltransferase involved in dehydrophos biosynthesis. Proc.Natl.Acad.Sci.USA, 107, 2010
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3OU6
| DhpI-SAM complex | Descriptor: | S-ADENOSYLMETHIONINE, SAM-dependent methyltransferase, SULFATE ION | Authors: | Bae, B, Nair, S.K. | Deposit date: | 2010-09-14 | Release date: | 2010-10-27 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Characterization and structure of DhpI, a phosphonate O-methyltransferase involved in dehydrophos biosynthesis. Proc.Natl.Acad.Sci.USA, 107, 2010
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6IKX
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6IKZ
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6K8D
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6KNL
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6KNJ
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4QD4
| Structure of ADC-68, a Novel Carbapenem-Hydrolyzing Class C Extended-Spectrum -Lactamase from Acinetobacter baumannii | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Beta-lactamase ADC-68, CITRIC ACID | Authors: | Hong, M.K, Kang, L.W. | Deposit date: | 2014-05-13 | Release date: | 2015-01-21 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structure of ADC-68, a novel carbapenem-hydrolyzing class C extended-spectrum beta-lactamase isolated from Acinetobacter baumannii Acta Crystallogr.,Sect.D, 70, 2014
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8HNP
| Archaeal transcription factor Mutant | Descriptor: | Archaeal transcription regulator | Authors: | Bae, D.W, Cha, S.S. | Deposit date: | 2022-12-08 | Release date: | 2023-09-13 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3.39 Å) | Cite: | An archaeal transcription factor EnfR with a novel 'eighth note' fold controls hydrogen production of a hyperthermophilic archaeon Thermococcus onnurineus NA1. Nucleic Acids Res., 51, 2023
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8HNO
| Archaeal transcription factor Wild type | Descriptor: | Archaeal transcription regulator | Authors: | Bae, D.W, Cha, S.S. | Deposit date: | 2022-12-08 | Release date: | 2023-09-13 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.84 Å) | Cite: | An archaeal transcription factor EnfR with a novel 'eighth note' fold controls hydrogen production of a hyperthermophilic archaeon Thermococcus onnurineus NA1. Nucleic Acids Res., 51, 2023
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8K55
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8K57
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5GZW
| Crystal structure of AmpC BER adenylylated by acetyl-AMP | Descriptor: | ADENOSINE MONOPHOSPHATE, Beta-lactamase, SULFATE ION | Authors: | An, Y.J, Cha, S.S. | Deposit date: | 2016-10-02 | Release date: | 2017-10-11 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.489 Å) | Cite: | Structural and mechanistic insights into the inhibition of class C beta-lactamases through the adenylylation of the nucleophilic serine. J.Antimicrob.Chemother., 72, 2017
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5F1G
| Crystal structure of AmpC BER adenylylated in the cytoplasm | Descriptor: | 1,2-ETHANEDIOL, ADENOSINE MONOPHOSPHATE, Beta-lactamase, ... | Authors: | An, Y.J, Kim, M.K, Na, J.H, Cha, S.S. | Deposit date: | 2015-11-30 | Release date: | 2016-12-07 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | Structural and mechanistic insights into the inhibition of class C beta-lactamases through the adenylylation of the nucleophilic serine. J.Antimicrob.Chemother., 72, 2017
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5F1F
| Crystal structure of CMY-10 adenylylated by acetyl-AMP | Descriptor: | ADENOSINE MONOPHOSPHATE, Beta-lactamase, CADMIUM ION | Authors: | An, Y.J, Kim, M.K, Na, J.H, Cha, S.S. | Deposit date: | 2015-11-30 | Release date: | 2016-12-07 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.548 Å) | Cite: | Structural and mechanistic insights into the inhibition of class C beta-lactamases through the adenylylation of the nucleophilic serine. J.Antimicrob.Chemother., 72, 2017
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4XGS
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7D24
| Hsp90 alpha N-terminal domain in complex with a 4B compund | Descriptor: | 9-[(3-tert-butyl-1,2-oxazol-5-yl)methyl]-6-chloranyl-purin-2-amine, Heat shock protein HSP 90-alpha | Authors: | Shin, S.C, Kim, E.E. | Deposit date: | 2020-09-15 | Release date: | 2021-07-28 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Structural Basis for Design of New Purine-Based Inhibitors Targeting the Hydrophobic Binding Pocket of Hsp90. Int J Mol Sci, 21, 2020
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7D26
| Hsp90 alpha N-terminal domain in complex with a 8 compund | Descriptor: | 6-chloranyl-9-[(2-phenyl-1,3-oxazol-5-yl)methyl]purin-2-amine, Heat shock protein HSP 90-alpha | Authors: | Shin, S.C, Kim, E.E. | Deposit date: | 2020-09-15 | Release date: | 2021-07-28 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structural Basis for Design of New Purine-Based Inhibitors Targeting the Hydrophobic Binding Pocket of Hsp90. Int J Mol Sci, 21, 2020
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7D22
| Hsp90 alpha N-terminal domain in complex with a 6B compund | Descriptor: | 9-[(3-tert-butyl-1,2-oxazol-5-yl)methyl]-6-chloranyl-purin-2-amine, Heat shock protein HSP 90-alpha | Authors: | Shin, S.C, Kim, E.E. | Deposit date: | 2020-09-15 | Release date: | 2021-07-28 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structural Basis for Design of New Purine-Based Inhibitors Targeting the Hydrophobic Binding Pocket of Hsp90. Int J Mol Sci, 21, 2020
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7D25
| Hsp90 alpha N-terminal domain in complex with a 14 compund | Descriptor: | 6-chloranyl-9-[(4-methylphenyl)methyl]purin-2-amine, Heat shock protein HSP 90-alpha | Authors: | Shin, S.C, Kim, E.E. | Deposit date: | 2020-09-15 | Release date: | 2021-07-28 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Structural Basis for Design of New Purine-Based Inhibitors Targeting the Hydrophobic Binding Pocket of Hsp90. Int J Mol Sci, 21, 2020
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7D1V
| Hsp90 alpha N-terminal domain in complex with a 6C compund | Descriptor: | 6-chloranyl-9-[(3-propan-2-yl-1,2-oxazol-5-yl)methyl]purin-2-amine, Heat shock protein HSP 90-alpha | Authors: | Shin, S.C, Kim, E.E. | Deposit date: | 2020-09-15 | Release date: | 2021-07-28 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.332 Å) | Cite: | Structural Basis for Design of New Purine-Based Inhibitors Targeting the Hydrophobic Binding Pocket of Hsp90. Int J Mol Sci, 21, 2020
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